3LAIA

Structural insights into the molecular mechanism of h-nox activation
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
188
structure length
188
Chain Sequence
MKGTIVGTWIKTLRDLYGNDVVDESLKSVGWEPDRVITPLEDIDDDEVRRIFAKVSEKTGKNVNEIWREVGRQNIKTFSEWFPSYFAGRRLVNFLMMMDEVGLQLTKMIKGATPPRLIAKPVAKDAIEMEYVSKRKMYDYFLGLIEGSSKFFKEEISVEEVERGEKDGFSRLKVRIKFKNPVFEYKKN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into the molecular mechanism of H-NOX activation.
pubmed doi rcsb
molecule tags Signaling protein
source organism Thermoanaerobacter tengcongensis
molecule keywords Methyl-accepting chemotaxis protein
total genus 59
structure length 188
sequence length 188
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2010-01-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07700 HNOB Haem-NO-binding
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1520.10 Alpha Beta Alpha-Beta Complex H-NOX domain H-NOX domain 3laiA00
4IAEA 3TF8A 4U9KA 3SJ5A 3TF1A 3EEEA 3IQBA 4IAHA 3M0BA 3TFAA 3NVUA 2O0CA 3LAHA 3TFGA 4FDKA 5JRVA 4JQHA 3TFFA 2KIIA 3TF0A 3LAIA 3TFEA 2KILA 1U55A 5JRUA 4U9JA 1U56A 3TFDA 4IAMA 3TF9A 4U9BA 3NVRA 2O09A 5JRXA 4IT2A 3L6JA 4U99A 1XBNA 4U9GA 2O0GA 1U4HA
chains in the Genus database with same CATH superfamily
4IAEA 3TF8A 4U9KA 3SJ5A 3TF1A 3EEEA 3IQBA 4IAHA 3M0BA 3TFAA 3NVUA 2O0CA 3LAHA 3TFGA 4FDKA 5JRVA 4JQHA 3TFFA 2KIIA 3TF0A 3LAIA 3TFEA 2KILA 1U55A 5JRUA 4U9JA 1U56A 3TFDA 4IAMA 3TF9A 4U9BA 3NVRA 2O09A 5JRXA 4IT2A 3L6JA 4U99A 1XBNA 4U9GA 2O0GA 1U4HA
chains in the Genus database with same CATH topology
4IAEA 3TF8A 4U9KA 3SJ5A 3TF1A 3EEEA 3IQBA 4IAHA 3M0BA 3TFAA 3NVUA 2O0CA 3LAHA 3TFGA 4FDKA 5JRVA 4JQHA 3TFFA 2KIIA 3TF0A 3LAIA 3TFEA 2KILA 1U55A 5JRUA 4U9JA 1U56A 3TFDA 4IAMA 3TF9A 4U9BA 3NVRA 2O09A 5JRXA 4IT2A 3L6JA 4U99A 1XBNA 4U9GA 2O0GA 1U4HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IAE A;  3TF8 A;  4U9K A;  3SJ5 A;  3TF1 A;  3EEE A;  3IQB A;  4IAH A;  3M0B A;  3TFA A;  3NVU A;  2O0C A;  3LAH A;  3TFG A;  4FDK A;  5JRV A;  4JQH A;  3TFF A;  2KII A;  3TF0 A;  3LAI A;  3TFE A;  2KIL A;  1U55 A;  5JRU A;  4U9J A;  1U56 A;  3TFD A;  4IAM A;  3TF9 A;  4U9B A;  3NVR A;  2O09 A;  5JRX A;  4IT2 A;  3L6J A;  4U99 A;  1XBN A;  4U9G A;  2O0G A;  1U4H A; 
#chains in the Genus database with same CATH topology
 4IAE A;  3TF8 A;  4U9K A;  3SJ5 A;  3TF1 A;  3EEE A;  3IQB A;  4IAH A;  3M0B A;  3TFA A;  3NVU A;  2O0C A;  3LAH A;  3TFG A;  4FDK A;  5JRV A;  4JQH A;  3TFF A;  2KII A;  3TF0 A;  3LAI A;  3TFE A;  2KIL A;  1U55 A;  5JRU A;  4U9J A;  1U56 A;  3TFD A;  4IAM A;  3TF9 A;  4U9B A;  3NVR A;  2O09 A;  5JRX A;  4IT2 A;  3L6J A;  4U99 A;  1XBN A;  4U9G A;  2O0G A;  1U4H A; 
#chains in the Genus database with same CATH homology
 4IAE A;  3TF8 A;  4U9K A;  3SJ5 A;  3TF1 A;  3EEE A;  3IQB A;  4IAH A;  3M0B A;  3TFA A;  3NVU A;  2O0C A;  3LAH A;  3TFG A;  4FDK A;  5JRV A;  4JQH A;  3TFF A;  2KII A;  3TF0 A;  3LAI A;  3TFE A;  2KIL A;  1U55 A;  5JRU A;  4U9J A;  1U56 A;  3TFD A;  4IAM A;  3TF9 A;  4U9B A;  3NVR A;  2O09 A;  5JRX A;  4IT2 A;  3L6J A;  4U99 A;  1XBN A;  4U9G A;  2O0G A;  1U4H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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