4IAHA

Crystal structure of bay 60-2770 bound c139a h-nox domain with s-nitrosylated conserved c122
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
182
structure length
181
Chain Sequence
MYGLVNKAIQDMISKHHGEDTWEAIKQKAGLEDIDFFVGMEAYSDDVTYHLVGAASEVLGKPAEELLIAFGEYWVTYTSEEGYGELLASAGDSLPEFMENLDNLHARVGLSFPQLRPPAFEQHTSSKSMELHYQSTRAGLAPMVLGLLHGLGKRFQTKVEVTQTAFRETGEDHDIFSIKYE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase
molecule keywords Alr2278 protein
publication title Insights into BAY 60-2770 Activation and S-Nitrosylation-Dependent Desensitization of Soluble Guanylyl Cyclase via Crystal Structures of Homologous Nostoc H-NOX Domain Complexes.
pubmed doi rcsb
source organism Nostoc sp.
total genus 55
structure length 181
sequence length 182
chains with identical sequence B
ec nomenclature ec 4.6.1.2: Guanylate cyclase.
pdb deposition date 2012-12-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07700 HNOB Haem-NO-binding
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1520.10 Alpha Beta Alpha-Beta Complex H-NOX domain H-NOX domain 4iahA00
3IQBA 3LAHA 3LAIA 1U56A 3TFFA 4IAHA 4U9BA 1XBNA 2KIIA 3TF8A 3TFEA 5JRXA 4IAMA 4U99A 3M0BA 3TF0A 3EEEA 1U55A 4U9GA 4IT2A 5JRUA 3TFGA 3TFAA 2KILA 1U4HA 3TFDA 3SJ5A 3TF1A 2O0CA 2O09A 3NVRA 5JRVA 3TF9A 3L6JA 2O0GA 3NVUA 4FDKA 4JQHA 4IAEA 4U9KA 4U9JA
chains in the Genus database with same CATH superfamily
3IQBA 3LAHA 3LAIA 1U56A 3TFFA 4IAHA 4U9BA 1XBNA 2KIIA 3TF8A 3TFEA 5JRXA 4IAMA 4U99A 3M0BA 3TF0A 3EEEA 1U55A 4U9GA 4IT2A 5JRUA 3TFGA 3TFAA 2KILA 1U4HA 3TFDA 3SJ5A 3TF1A 2O0CA 2O09A 3NVRA 5JRVA 3TF9A 3L6JA 2O0GA 3NVUA 4FDKA 4JQHA 4IAEA 4U9KA 4U9JA
chains in the Genus database with same CATH topology
3IQBA 3LAHA 3LAIA 1U56A 3TFFA 4IAHA 4U9BA 1XBNA 2KIIA 3TF8A 3TFEA 5JRXA 4IAMA 4U99A 3M0BA 3TF0A 3EEEA 1U55A 4U9GA 4IT2A 5JRUA 3TFGA 3TFAA 2KILA 1U4HA 3TFDA 3SJ5A 3TF1A 2O0CA 2O09A 3NVRA 5JRVA 3TF9A 3L6JA 2O0GA 3NVUA 4FDKA 4JQHA 4IAEA 4U9KA 4U9JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3IQB A;  3LAH A;  3LAI A;  1U56 A;  3TFF A;  4IAH A;  4U9B A;  1XBN A;  2KII A;  3TF8 A;  3TFE A;  5JRX A;  4IAM A;  4U99 A;  3M0B A;  3TF0 A;  3EEE A;  1U55 A;  4U9G A;  4IT2 A;  5JRU A;  3TFG A;  3TFA A;  2KIL A;  1U4H A;  3TFD A;  3SJ5 A;  3TF1 A;  2O0C A;  2O09 A;  3NVR A;  5JRV A;  3TF9 A;  3L6J A;  2O0G A;  3NVU A;  4FDK A;  4JQH A;  4IAE A;  4U9K A;  4U9J A; 
#chains in the Genus database with same CATH topology
 3IQB A;  3LAH A;  3LAI A;  1U56 A;  3TFF A;  4IAH A;  4U9B A;  1XBN A;  2KII A;  3TF8 A;  3TFE A;  5JRX A;  4IAM A;  4U99 A;  3M0B A;  3TF0 A;  3EEE A;  1U55 A;  4U9G A;  4IT2 A;  5JRU A;  3TFG A;  3TFA A;  2KIL A;  1U4H A;  3TFD A;  3SJ5 A;  3TF1 A;  2O0C A;  2O09 A;  3NVR A;  5JRV A;  3TF9 A;  3L6J A;  2O0G A;  3NVU A;  4FDK A;  4JQH A;  4IAE A;  4U9K A;  4U9J A; 
#chains in the Genus database with same CATH homology
 3IQB A;  3LAH A;  3LAI A;  1U56 A;  3TFF A;  4IAH A;  4U9B A;  1XBN A;  2KII A;  3TF8 A;  3TFE A;  5JRX A;  4IAM A;  4U99 A;  3M0B A;  3TF0 A;  3EEE A;  1U55 A;  4U9G A;  4IT2 A;  5JRU A;  3TFG A;  3TFA A;  2KIL A;  1U4H A;  3TFD A;  3SJ5 A;  3TF1 A;  2O0C A;  2O09 A;  3NVR A;  5JRV A;  3TF9 A;  3L6J A;  2O0G A;  3NVU A;  4FDK A;  4JQH A;  4IAE A;  4U9K A;  4U9J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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