3MJIA

Activation of catalytic cysteine without a base in a mutant penicillin acylase precursor
Total Genus 98
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
98
sequence length
334
structure length
334
Chain Sequence
MLGSSSLSIRTTDDKSLFARTMDFTMEPDSKVIIVPRNYGIRLLEKENVVINNSYAFVGMGSTDITSPVLYDGVNEKGLMGAMLYYATFATYADEPKKGTRGINPVYVISQVLGNCVTVDDVIEKLTSYTLLNEANIILGFAPPLHYTFTDASGESIVIEPDKTGITIHRKTIGVMTNSPGYEWHQTNLRAYIGVTPNPPQDIMMGDLDLTPFGQGAGGLGLPGDFTPSARFLRVAYWKKYTEKAKNETEGVTNLFHILSSVNIPKGVVLTNEGKTDYTIYTSAMCAQSKNYYFKLYDNSRISAVSLMAENLNSQDLITFEWDRKQDIKQLNQV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Activation of catalytic cysteine without a base in a Mutant Penicillin Acylase Precursor
rcsb
molecule tags Hydrolase
source organism Bacillus sphaericus
molecule keywords Penicillin acylase
total genus 98
structure length 334
sequence length 334
chains with identical sequence B, C, D
ec nomenclature ec 3.5.1.11: Penicillin amidase.
pdb deposition date 2010-04-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02275 CBAH Linear amide C-N hydrolases, choloylglycine hydrolase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.60.10 Alpha Beta 4-Layer Sandwich Penicillin V Acylase; Chain A Penicillin V Acylase; Chain A 3mjiA00
2Z71A 3MJIA 3PVAA 2RG2A 3GVZA 2X1EA 2HF0A 3HBCA 5HKEA 4WL3A 2QUYA 4WL2A 2OQCA 2BJGA 2X1DA 2HEZA 2IWMA 2BJFA 2RF8A 2RLCA 2X1CA 2PVAA
chains in the Genus database with same CATH superfamily
2Z71A 3MJIA 3PVAA 2RG2A 3GVZA 3FGWA 2X1EA 2HF0A 3HBCA 5HKEA 3FGTB 4WL3A 2QUYA 4WL2A 2OQCA 3FGRB 4BWCB 2BJGA 2X1DA 2HEZA 3FBXA 2IWMA 2BJFA 2RF8A 2RLCA 2X1CA 2PVAA
chains in the Genus database with same CATH topology
2Z71A 3MJIA 3PVAA 2RG2A 3GVZA 3FGWA 2X1EA 2HF0A 3HBCA 5HKEA 3FGTB 4WL3A 2QUYA 4WL2A 2OQCA 3FGRB 4BWCB 2BJGA 2X1DA 2HEZA 3FBXA 2IWMA 2BJFA 2RF8A 2RLCA 2X1CA 2PVAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Z71 A;  3MJI A;  3PVA A;  2RG2 A;  3GVZ A;  2X1E A;  2HF0 A;  3HBC A;  5HKE A;  4WL3 A;  2QUY A;  4WL2 A;  2OQC A;  2BJG A;  2X1D A;  2HEZ A;  2IWM A;  2BJF A;  2RF8 A;  2RLC A;  2X1C A;  2PVA A; 
#chains in the Genus database with same CATH topology
 2Z71 A;  3MJI A;  3PVA A;  2RG2 A;  3GVZ A;  3FGW A;  2X1E A;  2HF0 A;  3HBC A;  5HKE A;  3FGT B;  4WL3 A;  2QUY A;  4WL2 A;  2OQC A;  3FGR B;  4BWC B;  2BJG A;  2X1D A;  2HEZ A;  3FBX A;  2IWM A;  2BJF A;  2RF8 A;  2RLC A;  2X1C A;  2PVA A; 
#chains in the Genus database with same CATH homology
 2Z71 A;  3MJI A;  3PVA A;  2RG2 A;  3GVZ A;  3FGW A;  2X1E A;  2HF0 A;  3HBC A;  5HKE A;  3FGT B;  4WL3 A;  2QUY A;  4WL2 A;  2OQC A;  3FGR B;  4BWC B;  2BJG A;  2X1D A;  2HEZ A;  3FBX A;  2IWM A;  2BJF A;  2RF8 A;  2RLC A;  2X1C A;  2PVA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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