3S8VX

Crystal structure of lrp6-dkk1 complex
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
82
structure length
73
Chain Sequence
QEGSVCLRSSDCASGLCCARHFWSKICKPVLKEGQVCTKHRRKGSHGLEIFQRCYCGEGLSCRIQSRLHTCQR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structures of the extracellular domain of LRP6 and its complex with DKK1.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Low-density lipoprotein receptor-related protein 6
total genus 16
structure length 73
sequence length 82
ec nomenclature
pdb deposition date 2011-05-31
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.80.10 Mainly Beta Ribbon Lipase, subunit A Lipase, subunit A 3s8vX00
2JTKA 1IMTA 1LPAA 2KRAA 3S2KC 1N8SC 1ETHB 1PCOA 2N8KA 1PCNA 5FWWC 3S8VX 1LPBA
chains in the Genus database with same CATH superfamily
2JTKA 1IMTA 1LPAA 2KRAA 3S2KC 1N8SC 3BT4A 1ETHB 1PCOA 2N8KA 1PCNA 5FWWC 3S8VX 1LPBA
chains in the Genus database with same CATH topology
2JTKA 1IMTA 1LPAA 2KRAA 3S2KC 1N8SC 3BT4A 1ETHB 1PCOA 2N8KA 1PCNA 5FWWC 3S8VX 1LPBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JTK A;  1IMT A;  1LPA A;  2KRA A;  3S2K C;  1N8S C;  1ETH B;  1PCO A;  2N8K A;  1PCN A;  5FWW C;  3S8V X;  1LPB A; 
#chains in the Genus database with same CATH topology
 2JTK A;  1IMT A;  1LPA A;  2KRA A;  3S2K C;  1N8S C;  3BT4 A;  1ETH B;  1PCO A;  2N8K A;  1PCN A;  5FWW C;  3S8V X;  1LPB A; 
#chains in the Genus database with same CATH homology
 2JTK A;  1IMT A;  1LPA A;  2KRA A;  3S2K C;  1N8S C;  3BT4 A;  1ETH B;  1PCO A;  2N8K A;  1PCN A;  5FWW C;  3S8V X;  1LPB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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