5FWWC

Wnt modulator kremen in complex with dkk1 (crd2) and lrp6 (pe3pe4)
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
85
structure length
76
Chain Sequence
KGQEGSVCLRSSDCASGLCCARHFWSKICKPVLKEGQVCTKHRRKGSHGLEIFQRCYCGEGLSCRIQKRLHTCQRH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 6
publication title Structure of the Dual-Mode Wnt Regulator Kremen1 and Insight Into Ternary Complex Formation with Lrp6 and Dickkopf
pubmed doi rcsb
source organism Homo sapiens
total genus 15
structure length 76
sequence length 85
ec nomenclature
pdb deposition date 2016-02-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.80.10 Mainly Beta Ribbon Lipase, subunit A Lipase, subunit A 5fwwC00
5FWWC 2JTKA 1IMTA 2KRAA 1PCNA 2N8KA 3S8VX 3S2KC 1PCOA 1N8SC 1LPAA 1ETHB 1LPBA
chains in the Genus database with same CATH superfamily
3BT4A 5FWWC 2JTKA 1IMTA 2KRAA 1PCNA 2N8KA 3S8VX 3S2KC 1PCOA 1N8SC 1LPAA 1ETHB 1LPBA
chains in the Genus database with same CATH topology
3BT4A 5FWWC 2JTKA 1IMTA 2KRAA 1PCNA 2N8KA 3S8VX 3S2KC 1PCOA 1N8SC 1LPAA 1ETHB 1LPBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5FWW C;  2JTK A;  1IMT A;  2KRA A;  1PCN A;  2N8K A;  3S8V X;  3S2K C;  1PCO A;  1N8S C;  1LPA A;  1ETH B;  1LPB A; 
#chains in the Genus database with same CATH topology
 3BT4 A;  5FWW C;  2JTK A;  1IMT A;  2KRA A;  1PCN A;  2N8K A;  3S8V X;  3S2K C;  1PCO A;  1N8S C;  1LPA A;  1ETH B;  1LPB A; 
#chains in the Genus database with same CATH homology
 3BT4 A;  5FWW C;  2JTK A;  1IMT A;  2KRA A;  1PCN A;  2N8K A;  3S8V X;  3S2K C;  1PCO A;  1N8S C;  1LPA A;  1ETH B;  1LPB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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