3TVLA

Complex between the human thiamine triphosphatase and triphosphate
Total Genus 56
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
211
structure length
204
Chain Sequence
GLIEVERKFLPGPGTEERLQELGGTLEYRVTFRDTYYDTPELSLMQADHWLRRREDSGWELKCPGAAGVLGPHTEYKELTAEPTIVAQLCKVLRADGLGAGDVAAVLGPLGLQEVASFVTKRSAWKLVLPQLRVDLDTADFGYAVGEVEALVHEEAEVPTALEKIHRLSSMLGVPAQETAPAKLIVYLQRFRPQDYQRLLEVNS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Hydrolase
molecule keywords Thiamine-triphosphatase
publication title Structural determinants of specificity and catalytic mechanism in mammalian 25-kDa thiamine triphosphatase.
pubmed doi rcsb
source organism Homo sapiens
total genus 56
structure length 204
sequence length 211
chains with identical sequence B
ec nomenclature ec 3.6.1.28: Thiamine-triphosphatase.
pdb deposition date 2011-09-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01928 CYTH CYTH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.320.10 Mainly Beta Beta Barrel Hypothetical Protein Pfu-838710-001 Hypothetical Protein Pfu-838710-001 3tvlA00
5A65A 2GFGA 5A67A 2DC4A 5A64A 2JMUA 3BHDA 3N0ZA 2HZMB 5A66A 2HZSB 3SY3A 2FBLA 3TYPA 3TJ7A 3N10A 2ACAA 2EENA 2FJTA 3C0TA 3V85A 1YEMA 5A5YA 4H63R 3N0YA 3TVLA 5A68A
chains in the Genus database with same CATH superfamily
3G3UA 5A65A 2GFGA 3G3QA 5A67A 2DC4A 5A64A 3N0ZA 2JMUA 3BHDA 2HZMB 5A66A 2HZSB 2FBLA 3SY3A 3TYPA 3TJ7A 3N10A 2ACAA 2EENA 2FJTA 3C0TA 3G3RA 3G3TA 3V85A 1YEMA 3G3OA 5A5YA 4H63R 3N0YA 3TVLA 5A68A
chains in the Genus database with same CATH topology
3G3UA 5A65A 2GFGA 3G3QA 5A67A 2DC4A 5A64A 3N0ZA 2JMUA 3BHDA 2HZMB 5A66A 2HZSB 2FBLA 3SY3A 3TYPA 3TJ7A 3N10A 2ACAA 2EENA 2FJTA 3C0TA 3G3RA 3G3TA 3V85A 1YEMA 3G3OA 5A5YA 4H63R 3N0YA 3TVLA 5A68A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5A65 A;  2GFG A;  5A67 A;  2DC4 A;  5A64 A;  2JMU A;  3BHD A;  3N0Z A;  2HZM B;  5A66 A;  2HZS B;  3SY3 A;  2FBL A;  3TYP A;  3TJ7 A;  3N10 A;  2ACA A;  2EEN A;  2FJT A;  3C0T A;  3V85 A;  1YEM A;  5A5Y A;  4H63 R;  3N0Y A;  3TVL A;  5A68 A; 
#chains in the Genus database with same CATH topology
 3G3U A;  5A65 A;  2GFG A;  3G3Q A;  5A67 A;  2DC4 A;  5A64 A;  3N0Z A;  2JMU A;  3BHD A;  2HZM B;  5A66 A;  2HZS B;  2FBL A;  3SY3 A;  3TYP A;  3TJ7 A;  3N10 A;  2ACA A;  2EEN A;  2FJT A;  3C0T A;  3G3R A;  3G3T A;  3V85 A;  1YEM A;  3G3O A;  5A5Y A;  4H63 R;  3N0Y A;  3TVL A;  5A68 A; 
#chains in the Genus database with same CATH homology
 3G3U A;  5A65 A;  2GFG A;  3G3Q A;  5A67 A;  2DC4 A;  5A64 A;  3N0Z A;  2JMU A;  3BHD A;  2HZM B;  5A66 A;  2HZS B;  2FBL A;  3SY3 A;  3TYP A;  3TJ7 A;  3N10 A;  2ACA A;  2EEN A;  2FJT A;  3C0T A;  3G3R A;  3G3T A;  3V85 A;  1YEM A;  3G3O A;  5A5Y A;  4H63 R;  3N0Y A;  3TVL A;  5A68 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...