5A65A

Crystal structure of mouse thiamine triphosphatase in complex with thiamine diphosphate, orthophosphate and magnesium ions.
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
216
structure length
208
Chain Sequence
GAMTQGLIEVERKFAPGPDTEERLQELGATLEHRVTFRDTYYDTSELSLMLSDHWLRQREGSGWELKCPGVSGPHNEYVEVTSEAAIVAQLFELLGSGEQKPAGVAAVLGSLKLQEVASFITTRSSWKLALSEPQLTIDLDSADFGYAVGEVEAMVHEKAEVPAALEKIITVSSMLGVPAQEEAPAKLMVYLQRFRPLDYQRLLEAAS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords THIAMINE TRIPHOSPHATASE
publication title Structural Determinants for Substrate Binding and Catalysis in Triphosphate Tunnel Metalloenzymes.
pubmed doi rcsb
source organism Mus musculus
total genus 51
structure length 208
sequence length 216
chains with identical sequence B
ec nomenclature ec 3.6.1.28: Thiamine-triphosphatase.
pdb deposition date 2015-06-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01928 CYTH CYTH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.320.10 Mainly Beta Beta Barrel Hypothetical Protein Pfu-838710-001 Hypothetical Protein Pfu-838710-001 5a65A00
5A5YA 3N0ZA 2JMUA 3N10A 4H63R 5A66A 2DC4A 1YEMA 5A68A 2ACAA 2HZMB 2EENA 3TVLA 3TYPA 3C0TA 5A64A 3V85A 5A67A 5A65A 3BHDA 2FJTA 2HZSB 2GFGA 3TJ7A 3N0YA 2FBLA 3SY3A
chains in the Genus database with same CATH superfamily
3G3TA 3G3QA 5A5YA 3N0ZA 2JMUA 3N10A 4H63R 5A66A 2DC4A 1YEMA 5A68A 2ACAA 2HZMB 2EENA 3TVLA 3TYPA 3C0TA 3G3OA 5A64A 3V85A 3G3UA 5A67A 5A65A 3BHDA 2FJTA 2HZSB 2GFGA 3TJ7A 3N0YA 2FBLA 3G3RA 3SY3A
chains in the Genus database with same CATH topology
3G3TA 3G3QA 5A5YA 3N0ZA 2JMUA 3N10A 4H63R 5A66A 2DC4A 1YEMA 5A68A 2ACAA 2HZMB 2EENA 3TVLA 3TYPA 3C0TA 3G3OA 5A64A 3V85A 3G3UA 5A67A 5A65A 3BHDA 2FJTA 2HZSB 2GFGA 3TJ7A 3N0YA 2FBLA 3G3RA 3SY3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5A5Y A;  3N0Z A;  2JMU A;  3N10 A;  4H63 R;  5A66 A;  2DC4 A;  1YEM A;  5A68 A;  2ACA A;  2HZM B;  2EEN A;  3TVL A;  3TYP A;  3C0T A;  5A64 A;  3V85 A;  5A67 A;  5A65 A;  3BHD A;  2FJT A;  2HZS B;  2GFG A;  3TJ7 A;  3N0Y A;  2FBL A;  3SY3 A; 
#chains in the Genus database with same CATH topology
 3G3T A;  3G3Q A;  5A5Y A;  3N0Z A;  2JMU A;  3N10 A;  4H63 R;  5A66 A;  2DC4 A;  1YEM A;  5A68 A;  2ACA A;  2HZM B;  2EEN A;  3TVL A;  3TYP A;  3C0T A;  3G3O A;  5A64 A;  3V85 A;  3G3U A;  5A67 A;  5A65 A;  3BHD A;  2FJT A;  2HZS B;  2GFG A;  3TJ7 A;  3N0Y A;  2FBL A;  3G3R A;  3SY3 A; 
#chains in the Genus database with same CATH homology
 3G3T A;  3G3Q A;  5A5Y A;  3N0Z A;  2JMU A;  3N10 A;  4H63 R;  5A66 A;  2DC4 A;  1YEM A;  5A68 A;  2ACA A;  2HZM B;  2EEN A;  3TVL A;  3TYP A;  3C0T A;  3G3O A;  5A64 A;  3V85 A;  3G3U A;  5A67 A;  5A65 A;  3BHD A;  2FJT A;  2HZS B;  2GFG A;  3TJ7 A;  3N0Y A;  2FBL A;  3G3R A;  3SY3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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