The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
287
|
sequence length |
733
|
structure length |
733
|
Chain Sequence |
LLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELRSHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPALYDHVVKMVEMGKYDNHLLEDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLYILVAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTPTRQFSSCVLIECGDSLDSINATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMDYGVQINKLMYTRLLKGEDITLFSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQRVKAVELFSLMMQERASTGRIYIQNVDHCNTHSPFDPAIAPVRQSNLCLEIALPTKPLNDVNDENGEIALCTLSAFNLGAINNLDELEELAILAVRALDALLDYQDYPIPAAKRGAMGRRTLGIGVINFAYYLAKHGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACPWFNETTYAKGILPIDTYKKDLDTIANEPLHYDWEALRESIKTHGLRNSTLSALMPSETSSQISNATNGIEPPRGYVSIKASKDGILRQVVPDYEHLHDAYELLWEMPGNDGYLQLVGIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKTLYYQNTRDG
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding.
pubmed doi rcsb |
| molecule tags |
Complex (oxidoreductase/peptide)
|
| source organism |
Escherichia coli
|
| molecule keywords |
RIBONUCLEOTIDE REDUCTASE R1 PROTEIN
|
| total genus |
287
|
| structure length |
733
|
| sequence length |
733
|
| chains with identical sequence |
B, C
|
| ec nomenclature |
ec
1.17.4.1: Ribonucleoside-diphosphate reductase. |
| pdb deposition date | 1997-07-21 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00317 | Ribonuc_red_lgN | Ribonucleotide reductase, all-alpha domain |
| A | PF02867 | Ribonuc_red_lgC | Ribonucleotide reductase, barrel domain |
| A | PF03477 | ATP-cone | ATP cone domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | Alpha-Beta Barrel | Anaerobic Ribonucleotide-triphosphate Reductase Large Chain | Anaerobic Ribonucleotide-triphosphate Reductase Large Chain |
#chains in the Genus database with same CATH superfamily 2F3O A; 2CVX A; 3O0O A; 2WGH A; 1H7B A; 3S8C A; 2R1R A; 3O0Q A; 3S8A A; 1H79 A; 7R1R A; 5CNT A; 2XAZ A; 3TB9 A; 5R1R A; 1XJF A; 1XJK A; 1XJJ A; 1H78 A; 2Y8N A; 2X0X A; 2CVS A; 2ZLG A; 1XJN A; 2XAV A; 2XAX A; 3RSR A; 3PFL A; 1H18 A; 2CVY A; 1H7A A; 3O0N A; 1CM5 A; 2YAJ A; 2CVT A; 4MTJ A; 2XAP A; 4R1R A; 5CNS A; 2XAK A; 1R1R A; 3HNC A; 1HK8 A; 5CNU A; 4X3V A; 1PEM A; 5CNV A; 1R8W A; 2XAY A; 1PEO A; 3S8B A; 1ZZD A; 3R1R A; 1XJE A; 4ERM A; 2XO5 A; 2BQ1 E; 2CVU A; 1XJM A; 3HND A; 1PEU A; 1R9D A; 3TBA A; 3K8T A; 1L1L A; 3HNE A; 2XAW A; 1QHM A; 2XO4 A; 2PFL A; 3HNF A; 2HA9 A; 1H17 A; 2ZLF A; 1XJG A; 1PEQ A; 2CVW A; 3S87 A; 1RLR A; 2CVV A; 1H16 A; 1ZYZ A; 2EUD A; 1MZO A; 6R1R A; #chains in the Genus database with same CATH topology 5A0U A; 2F3O A; 2CVX A; 3O0O A; 2WGH A; 1H7B A; 3S8C A; 5A0Z A; 2R1R A; 3O0Q A; 3S8A A; 1H79 A; 7R1R A; 5CNT A; 2XAZ A; 3TB9 A; 5R1R A; 1XJF A; 5FAU A; 1XJK A; 1XJJ A; 1H78 A; 2Y8N A; 2X0X A; 5FAY A; 2CVS A; 2ZLG A; 1XJN A; 2XAV A; 2XAX A; 3RSR A; 3PFL A; 1H18 A; 2CVY A; 1H7A A; 3O0N A; 1CM5 A; 2YAJ A; 2CVT A; 4MTJ A; 2XAP A; 4R1R A; 5CNS A; 2XAK A; 1R1R A; 3HNC A; 1HK8 A; 5CNU A; 4X3V A; 1PEM A; 5CNV A; 1R8W A; 2XAY A; 1PEO A; 3S8B A; 1ZZD A; 3R1R A; 1XJE A; 4ERM A; 2XO5 A; 2BQ1 E; 2CVU A; 1XJM A; 3HND A; 1PEU A; 1R9D A; 3TBA A; 5KDP A; 3K8T A; 1L1L A; 3HNE A; 2XAW A; 1QHM A; 2XO4 A; 2PFL A; 3HNF A; 2HA9 A; 1H17 A; 2ZLF A; 1XJG A; 5FAV A; 1PEQ A; 2CVW A; 3S87 A; 1RLR A; 2CVV A; 1H16 A; 5FAW A; 1ZYZ A; 2EUD A; 1MZO A; 6R1R A; #chains in the Genus database with same CATH homology 5A0U A; 2F3O A; 2CVX A; 3O0O A; 2WGH A; 1H7B A; 3S8C A; 5A0Z A; 2R1R A; 3O0Q A; 3S8A A; 1H79 A; 7R1R A; 5CNT A; 2XAZ A; 3TB9 A; 5R1R A; 1XJF A; 5FAU A; 1XJK A; 1XJJ A; 1H78 A; 2Y8N A; 2X0X A; 5FAY A; 2CVS A; 2ZLG A; 1XJN A; 2XAV A; 2XAX A; 3RSR A; 3PFL A; 1H18 A; 2CVY A; 1H7A A; 3O0N A; 1CM5 A; 2YAJ A; 2CVT A; 4MTJ A; 2XAP A; 4R1R A; 5CNS A; 2XAK A; 1R1R A; 3HNC A; 1HK8 A; 5CNU A; 4X3V A; 1PEM A; 5CNV A; 1R8W A; 2XAY A; 1PEO A; 3S8B A; 1ZZD A; 3R1R A; 1XJE A; 4ERM A; 2XO5 A; 2BQ1 E; 2CVU A; 1XJM A; 3HND A; 1PEU A; 1R9D A; 3TBA A; 5KDP A; 3K8T A; 1L1L A; 3HNE A; 2XAW A; 1QHM A; 2XO4 A; 2PFL A; 3HNF A; 2HA9 A; 1H17 A; 2ZLF A; 1XJG A; 5FAV A; 1PEQ A; 2CVW A; 3S87 A; 1RLR A; 2CVV A; 1H16 A; 5FAW A; 1ZYZ A; 2EUD A; 1MZO A; 6R1R A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
