4DKBA

Crystal structure of trypanosoma brucei dutpase with dupnp and ca2+
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
279
structure length
223
Chain Sequence
VSLSPLILRSLAELQDGLNTVVDKNWRQLRRPGDWSLAITMEAAELLDSYPWKWWKNVKAQPDLQNVKIELTDILHFSLSGAMQVSDENDLADFMFFPLSDTNNALASFQNIIRLASLQRFQLVTSAVIAAADDIGFNLVAYYVAKHTLNGIRQMKGYKDGTYVKVQKGVEDNELLHGCISPFSLDDVTNEGNYKTKWDDIMHRVYDAFGTPKEERLNIGHWL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title On the catalytic mechanism of dimeric dUTPases.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Trypanosoma brucei
molecule keywords Deoxyuridine triphosphatase
total genus 94
structure length 223
sequence length 279
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2012-02-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08761 dUTPase_2 dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.4010.10 Mainly Alpha Orthogonal Bundle all-alpha NTP pyrophosphatase fold Type II deoxyuridine triphosphatase 4dkbA00
1W2YA 2CICA 4DKBA 4DK4A 4DL8A 4DLCA
chains in the Genus database with same CATH superfamily
1W2YA 2CICA 4DKBA 4DK4A 4DL8A 4DLCA
chains in the Genus database with same CATH topology
1W2YA 2YB0A 2CJEA 2CICA 4DKBA 2YAYA 1OGLA 4DK4A 2YAZA 1OGKA 4DL8A 4DLCA 4DK2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1W2Y A;  2CIC A;  4DKB A;  4DK4 A;  4DL8 A;  4DLC A; 
#chains in the Genus database with same CATH topology
 1W2Y A;  2CIC A;  4DKB A;  4DK4 A;  4DL8 A;  4DLC A; 
#chains in the Genus database with same CATH homology
 1W2Y A;  2YB0 A;  2CJE A;  2CIC A;  4DKB A;  2YAY A;  1OGL A;  4DK4 A;  2YAZ A;  1OGK A;  4DL8 A;  4DLC A;  4DK2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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