4IAE | Genus

Total Genus 59

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	59
sequence length	182
structure length	182
Chain Sequence	MYGLVNKAIQDMISKHHGEDTWEAIKQKAGLEDIDFFVGMEAYSDDVTYHLVGAASEVLGKPAEELLIAFGEYWVTYTSEEGYGELLASAGDSLPEFMENLDNLHARVGLSFPQLRPPAFECQHTSSKSMELHYQSTRAGLAPMVLGLLHGLGKRFQTKVEVTQTAFRETGEDHDIFSIKYE

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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Time for openFile(/file/5d0057e0bb1c97f61f5c7aa1/pdb.gz): 1225 ms

reading 182 atoms

ModelSet: haveSymmetry:false haveUnitcells:false haveFractionalCoord:false

1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

Default Van der Waals type for model set to Jmol

182 atoms created

ModelSet: autobonding; use autobond=false to not generate bonds automatically

Time for creating model: 20 ms

Adding embedded #jmolscript: select ({0:181});backbone only;select *;

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Lyase
source organism	Nostoc sp.
publication title	Insights into BAY 60-2770 Activation and S-Nitrosylation-Dependent Desensitization of Soluble Guanylyl Cyclase via Crystal Structures of Homologous Nostoc H-NOX Domain Complexes. pubmed doi rcsb
molecule keywords	Alr2278 protein
total genus	59
structure length	182
sequence length	182
chains with identical sequence	B
ec nomenclature	ec 4.6.1.2: Guanylate cyclase.
pdb deposition date	2012-12-06

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF07700	HNOB	Haem-NO-binding

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.90.1520.10	Alpha Beta	Alpha-Beta Complex	H-NOX domain	H-NOX domain	4iaeA00

3TF1A 1U4HA 4IAHA 2KIIA 4U9JA 3M0BA 3EEEA 3TFEA 2O09A 3TF8A 4U9GA 5JRVA 3TFAA 3TF9A 1XBNA 3NVUA 3TFGA 4IAEA 3TFDA 4JQHA 3SJ5A 3TF0A 3IQBA 4IT2A 4U9BA 3TFFA 2KILA 1U56A 3LAHA 4IAMA 1U55A 5JRXA 3LAIA 5JRUA 4U99A 4U9KA 3L6JA 2O0GA 3NVRA 2O0CA 4FDKA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 3TF1 A;  1U4H A;  4IAH A;  2KII A;  4U9J A;  3M0B A;  3EEE A;  3TFE A;  2O09 A;  3TF8 A;  4U9G A;  5JRV A;  3TFA A;  3TF9 A;  1XBN A;  3NVU A;  3TFG A;  4IAE A;  3TFD A;  4JQH A;  3SJ5 A;  3TF0 A;  3IQB A;  4IT2 A;  4U9B A;  3TFF A;  2KIL A;  1U56 A;  3LAH A;  4IAM A;  1U55 A;  5JRX A;  3LAI A;  5JRU A;  4U99 A;  4U9K A;  3L6J A;  2O0G A;  3NVR A;  2O0C A;  4FDK A; 
#chains in the Genus database with same CATH topology
 3TF1 A;  1U4H A;  4IAH A;  2KII A;  4U9J A;  3M0B A;  3EEE A;  3TFE A;  2O09 A;  3TF8 A;  4U9G A;  5JRV A;  3TFA A;  3TF9 A;  1XBN A;  3NVU A;  3TFG A;  4IAE A;  3TFD A;  4JQH A;  3SJ5 A;  3TF0 A;  3IQB A;  4IT2 A;  4U9B A;  3TFF A;  2KIL A;  1U56 A;  3LAH A;  4IAM A;  1U55 A;  5JRX A;  3LAI A;  5JRU A;  4U99 A;  4U9K A;  3L6J A;  2O0G A;  3NVR A;  2O0C A;  4FDK A; 
#chains in the Genus database with same CATH homology
 3TF1 A;  1U4H A;  4IAH A;  2KII A;  4U9J A;  3M0B A;  3EEE A;  3TFE A;  2O09 A;  3TF8 A;  4U9G A;  5JRV A;  3TFA A;  3TF9 A;  1XBN A;  3NVU A;  3TFG A;  4IAE A;  3TFD A;  4JQH A;  3SJ5 A;  3TF0 A;  3IQB A;  4IT2 A;  4U9B A;  3TFF A;  2KIL A;  1U56 A;  3LAH A;  4IAM A;  1U55 A;  5JRX A;  3LAI A;  5JRU A;  4U99 A;  4U9K A;  3L6J A;  2O0G A;  3NVR A;  2O0C A;  4FDK A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4IAEA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations