4IAMA

Crystal structure of the c139a mutant of nostoc h-nox domain
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
182
structure length
182
Chain Sequence
MYGLVNKAIQDMISKHHGEDTWEAIKQKAGLEDIDFFVGMEAYSDDVTYHLVGAASEVLGKPAEELLIAFGEYWVTYTSEEGYGELLASAGDSLPEFMENLDNLHARVGLSFPQLRPPAFECQHTSSKSMELHYQSTRAGLAPMVLGLLHGLGKRFQTKVEVTQTAFRETGEDHDIFSIKYE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Insights into BAY 60-2770 Activation and S-Nitrosylation-Dependent Desensitization of Soluble Guanylyl Cyclase via Crystal Structures of Homologous Nostoc H-NOX Domain Complexes.
pubmed doi rcsb
molecule tags Lyase
source organism Nostoc sp.
molecule keywords Alr2278 protein
total genus 59
structure length 182
sequence length 182
chains with identical sequence B
ec nomenclature ec 4.6.1.2: Guanylate cyclase.
pdb deposition date 2012-12-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07700 HNOB Haem-NO-binding
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1520.10 Alpha Beta Alpha-Beta Complex H-NOX domain H-NOX domain 4iamA00
3TF1A 3NVRA 4IAMA 3LAHA 2KILA 4U9KA 3M0BA 3LAIA 3L6JA 3TF9A 3IQBA 3TFFA 4JQHA 4U99A 4IT2A 1U56A 4FDKA 3TFAA 5JRXA 3SJ5A 2O0GA 3NVUA 4U9GA 5JRVA 4U9BA 2O09A 4U9JA 3TFDA 3TFGA 5JRUA 3TF8A 2O0CA 1XBNA 1U4HA 1U55A 3EEEA 3TF0A 2KIIA 4IAEA 3TFEA 4IAHA
chains in the Genus database with same CATH superfamily
3TF1A 3NVRA 4IAMA 3LAHA 2KILA 4U9KA 3M0BA 3LAIA 3L6JA 3TF9A 3IQBA 3TFFA 4JQHA 4U99A 4IT2A 1U56A 4FDKA 3TFAA 5JRXA 3SJ5A 2O0GA 3NVUA 4U9GA 5JRVA 4U9BA 2O09A 4U9JA 3TFDA 3TFGA 5JRUA 3TF8A 2O0CA 1XBNA 1U4HA 1U55A 3EEEA 3TF0A 2KIIA 4IAEA 3TFEA 4IAHA
chains in the Genus database with same CATH topology
3TF1A 3NVRA 4IAMA 3LAHA 2KILA 4U9KA 3M0BA 3LAIA 3L6JA 3TF9A 3IQBA 3TFFA 4JQHA 4U99A 4IT2A 1U56A 4FDKA 3TFAA 5JRXA 3SJ5A 2O0GA 3NVUA 4U9GA 5JRVA 4U9BA 2O09A 4U9JA 3TFDA 3TFGA 5JRUA 3TF8A 2O0CA 1XBNA 1U4HA 1U55A 3EEEA 3TF0A 2KIIA 4IAEA 3TFEA 4IAHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TF1 A;  3NVR A;  4IAM A;  3LAH A;  2KIL A;  4U9K A;  3M0B A;  3LAI A;  3L6J A;  3TF9 A;  3IQB A;  3TFF A;  4JQH A;  4U99 A;  4IT2 A;  1U56 A;  4FDK A;  3TFA A;  5JRX A;  3SJ5 A;  2O0G A;  3NVU A;  4U9G A;  5JRV A;  4U9B A;  2O09 A;  4U9J A;  3TFD A;  3TFG A;  5JRU A;  3TF8 A;  2O0C A;  1XBN A;  1U4H A;  1U55 A;  3EEE A;  3TF0 A;  2KII A;  4IAE A;  3TFE A;  4IAH A; 
#chains in the Genus database with same CATH topology
 3TF1 A;  3NVR A;  4IAM A;  3LAH A;  2KIL A;  4U9K A;  3M0B A;  3LAI A;  3L6J A;  3TF9 A;  3IQB A;  3TFF A;  4JQH A;  4U99 A;  4IT2 A;  1U56 A;  4FDK A;  3TFA A;  5JRX A;  3SJ5 A;  2O0G A;  3NVU A;  4U9G A;  5JRV A;  4U9B A;  2O09 A;  4U9J A;  3TFD A;  3TFG A;  5JRU A;  3TF8 A;  2O0C A;  1XBN A;  1U4H A;  1U55 A;  3EEE A;  3TF0 A;  2KII A;  4IAE A;  3TFE A;  4IAH A; 
#chains in the Genus database with same CATH homology
 3TF1 A;  3NVR A;  4IAM A;  3LAH A;  2KIL A;  4U9K A;  3M0B A;  3LAI A;  3L6J A;  3TF9 A;  3IQB A;  3TFF A;  4JQH A;  4U99 A;  4IT2 A;  1U56 A;  4FDK A;  3TFA A;  5JRX A;  3SJ5 A;  2O0G A;  3NVU A;  4U9G A;  5JRV A;  4U9B A;  2O09 A;  4U9J A;  3TFD A;  3TFG A;  5JRU A;  3TF8 A;  2O0C A;  1XBN A;  1U4H A;  1U55 A;  3EEE A;  3TF0 A;  2KII A;  4IAE A;  3TFE A;  4IAH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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