4JQHA

Crystal structure of a new sgc activator (analogue of bay 58-2667) bound to nostoc h-nox domain
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
182
structure length
182
Chain Sequence
MYGLVNKAIQDMISKHHGEDTWEAIKQKAGLEDIDFFVGMEAYSDDVTYHLVGAASEVLGKPAEELLIAFGEYWVTYTSEEGYGELLASAGDSLPEFMENLDNLHARVGLSFPQLRPPAFECQHTSSKSMELHYQSTRAGLAPMVLGLLHGLGKRFQTKVEVTQTAFRETGEDHDIFSIKYE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Insights into soluble guanylyl cyclase activation derived from improved heme-mimetics.
pubmed doi rcsb
molecule tags Signaling protein
source organism Nostoc sp.
molecule keywords Alr2278 protein
total genus 60
structure length 182
sequence length 182
chains with identical sequence B
ec nomenclature ec 4.6.1.2: Guanylate cyclase.
pdb deposition date 2013-03-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07700 HNOB Haem-NO-binding
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1520.10 Alpha Beta Alpha-Beta Complex H-NOX domain H-NOX domain 4jqhA00
3IQBA 3TF9A 1U55A 2KIIA 4IAEA 3LAHA 3TF8A 5JRXA 3TFDA 3LAIA 3NVUA 4U9KA 5JRUA 3TFGA 1U4HA 2O0GA 3NVRA 1U56A 3TFFA 3TF0A 3SJ5A 4IT2A 2KILA 4FDKA 4U9GA 3L6JA 2O09A 3TFAA 3M0BA 1XBNA 3TF1A 4U9BA 3EEEA 4IAMA 4JQHA 4U9JA 4U99A 5JRVA 3TFEA 4IAHA 2O0CA
chains in the Genus database with same CATH superfamily
3IQBA 3TF9A 1U55A 2KIIA 4IAEA 3LAHA 3TF8A 5JRXA 3TFDA 3LAIA 3NVUA 4U9KA 5JRUA 3TFGA 1U4HA 2O0GA 3NVRA 1U56A 3TFFA 3TF0A 3SJ5A 4IT2A 2KILA 4FDKA 4U9GA 3L6JA 2O09A 3TFAA 3M0BA 1XBNA 3TF1A 4U9BA 3EEEA 4IAMA 4JQHA 4U9JA 4U99A 5JRVA 3TFEA 4IAHA 2O0CA
chains in the Genus database with same CATH topology
3IQBA 3TF9A 1U55A 2KIIA 4IAEA 3LAHA 3TF8A 5JRXA 3TFDA 3LAIA 3NVUA 4U9KA 5JRUA 3TFGA 1U4HA 2O0GA 3NVRA 1U56A 3TFFA 3TF0A 3SJ5A 4IT2A 2KILA 4FDKA 4U9GA 3L6JA 2O09A 3TFAA 3M0BA 1XBNA 3TF1A 4U9BA 3EEEA 4IAMA 4JQHA 4U9JA 4U99A 5JRVA 3TFEA 4IAHA 2O0CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3IQB A;  3TF9 A;  1U55 A;  2KII A;  4IAE A;  3LAH A;  3TF8 A;  5JRX A;  3TFD A;  3LAI A;  3NVU A;  4U9K A;  5JRU A;  3TFG A;  1U4H A;  2O0G A;  3NVR A;  1U56 A;  3TFF A;  3TF0 A;  3SJ5 A;  4IT2 A;  2KIL A;  4FDK A;  4U9G A;  3L6J A;  2O09 A;  3TFA A;  3M0B A;  1XBN A;  3TF1 A;  4U9B A;  3EEE A;  4IAM A;  4JQH A;  4U9J A;  4U99 A;  5JRV A;  3TFE A;  4IAH A;  2O0C A; 
#chains in the Genus database with same CATH topology
 3IQB A;  3TF9 A;  1U55 A;  2KII A;  4IAE A;  3LAH A;  3TF8 A;  5JRX A;  3TFD A;  3LAI A;  3NVU A;  4U9K A;  5JRU A;  3TFG A;  1U4H A;  2O0G A;  3NVR A;  1U56 A;  3TFF A;  3TF0 A;  3SJ5 A;  4IT2 A;  2KIL A;  4FDK A;  4U9G A;  3L6J A;  2O09 A;  3TFA A;  3M0B A;  1XBN A;  3TF1 A;  4U9B A;  3EEE A;  4IAM A;  4JQH A;  4U9J A;  4U99 A;  5JRV A;  3TFE A;  4IAH A;  2O0C A; 
#chains in the Genus database with same CATH homology
 3IQB A;  3TF9 A;  1U55 A;  2KII A;  4IAE A;  3LAH A;  3TF8 A;  5JRX A;  3TFD A;  3LAI A;  3NVU A;  4U9K A;  5JRU A;  3TFG A;  1U4H A;  2O0G A;  3NVR A;  1U56 A;  3TFF A;  3TF0 A;  3SJ5 A;  4IT2 A;  2KIL A;  4FDK A;  4U9G A;  3L6J A;  2O09 A;  3TFA A;  3M0B A;  1XBN A;  3TF1 A;  4U9B A;  3EEE A;  4IAM A;  4JQH A;  4U9J A;  4U99 A;  5JRV A;  3TFE A;  4IAH A;  2O0C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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