4M5X | Genus

Total Genus 108

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	108
sequence length	346
structure length	339
Chain Sequence	KHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQK

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 339 atoms

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339 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hydrolase
source organism	Homo sapiens
publication title	A 2.2 angstrom resolution structure of the USP7 catalytic domain in a new space group elaborates upon structural rearrangements resulting from ubiquitin binding. pubmed doi rcsb
molecule keywords	Ubiquitin carboxyl-terminal hydrolase 7
total genus	108
structure length	339
sequence length	346
chains with identical sequence	B
ec nomenclature	ec 3.4.19.12: Ubiquitinyl hydrolase 1.
pdb deposition date	2013-08-08

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00443	UCH	Ubiquitin carboxyl-terminal hydrolase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.20.210.10	Mainly Beta	Single Sheet	ubp-family deubiquitinating enzyme fold	ubp-family deubiquitinating enzyme superfamily	4m5xA02

4M5WA 4M5XA 2F1ZA 1NBFA 1NB8A
chains in the Genus database with same CATH superfamily

4M5WA 3HRZC 4M5XA 3HS0C 2F1ZA 3FRPB 1NBFA 1NB8A
chains in the Genus database with same CATH topology

4M5WA 4M5XA 2F1ZA 1NBFA 1NB8A
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 4M5W A;  4M5X A;  2F1Z A;  1NBF A;  1NB8 A; 
#chains in the Genus database with same CATH topology
 4M5W A;  3HRZ C;  4M5X A;  3HS0 C;  2F1Z A;  3FRP B;  1NBF A;  1NB8 A; 
#chains in the Genus database with same CATH homology
 4M5W A;  4M5X A;  2F1Z A;  1NBF A;  1NB8 A;

...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4M5XA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations