4DK4A

Crystal structure of trypanosoma brucei dutpase with dupnp, ca2+ and na+
Total Genus 83
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
83
sequence length
279
structure length
218
Chain Sequence
SLSPLILRSLAELQDGLNTVVDKNWRQLRRPGDWSLAITMEAAELLDSYPWKWWKNVKAQPDLQNVKIELTDILHFSLSGAMQVSADFMFFPLSDTNNALASFQNIIRLASLQRFQLVTSAVIAAADDIGFNLVAYYVAKHTLNGIRQMKGYKDGTYVKVQKGVEDNELLHGCISPFSLDDVTNEGNYKTKWDDIMHRVYDAFGTPKEERLNIGHWLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title On the catalytic mechanism of dimeric dUTPases.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Trypanosoma brucei
molecule keywords Deoxyuridine triphosphatase
total genus 83
structure length 218
sequence length 279
chains with identical sequence B
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2012-02-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08761 dUTPase_2 dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.4010.10 Mainly Alpha Orthogonal Bundle all-alpha NTP pyrophosphatase fold Type II deoxyuridine triphosphatase 4dk4A00
4DKBA 4DK4A 4DL8A 4DLCA 1W2YA 2CICA
chains in the Genus database with same CATH superfamily
4DKBA 4DK4A 4DL8A 4DLCA 1W2YA 2CICA
chains in the Genus database with same CATH topology
2YAZA 4DL8A 4DKBA 2YAYA 4DLCA 1OGKA 4DK4A 2YB0A 2CJEA 4DK2A 1W2YA 1OGLA 2CICA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DKB A;  4DK4 A;  4DL8 A;  4DLC A;  1W2Y A;  2CIC A; 
#chains in the Genus database with same CATH topology
 4DKB A;  4DK4 A;  4DL8 A;  4DLC A;  1W2Y A;  2CIC A; 
#chains in the Genus database with same CATH homology
 2YAZ A;  4DL8 A;  4DKB A;  2YAY A;  4DLC A;  1OGK A;  4DK4 A;  2YB0 A;  2CJE A;  4DK2 A;  1W2Y A;  1OGL A;  2CIC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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