4QOYE

Novel binding motif and new flexibility revealed by structural analysis of a pyruvate dehydrogenase-dihydrolipoyl acetyltransferase sub-complex from the escherichia coli pyruvate dehydrogenase multi-enzyme complex
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
46
structure length
46
Chain Sequence
VHATPLIRRLAREFGVNLAKVKGTGRKGRILREDVQAYVKEAIKRA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Novel Binding Motif and New Flexibility Revealed by Structural Analyses of a Pyruvate Dehydrogenase-Dihydrolipoyl Acetyltransferase Subcomplex from the Escherichia coli Pyruvate Dehydrogenase Multienzyme Complex.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Escherichia coli
molecule keywords Pyruvate dehydrogenase E1 component
total genus 8
structure length 46
sequence length 46
chains with identical sequence F
ec nomenclature
pdb deposition date 2014-06-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF02817 E3_binding e3 binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.320.10 Few Secondary Structures Irregular Dihydrolipoamide Transferase E3-binding domain 4qoyE00
1W3DA 2PDEA 3DV0I 1W4FA 3DVAI 1W4KA 1W85I 1W4IA 1W4HA 1BALA 1W88I 1W4GA 2EQ9C 3RNME 1W4JA 1EBDC 1ZY8K 2WXCA 4QOYE 2BTGA 2BTHA 1ZWVA 2F5ZK 1W4EA 2F60K 2PDDA
chains in the Genus database with same CATH superfamily
1W3DA 2PDEA 3DV0I 1W4FA 3DVAI 1W4KA 1W85I 1W4IA 1W4HA 1BALA 1W88I 1W4GA 2EQ9C 3RNME 1W4JA 1EBDC 1ZY8K 2WXCA 4QOYE 2BTGA 2BTHA 1ZWVA 2F5ZK 1W4EA 2F60K 2PDDA
chains in the Genus database with same CATH topology
1W3DA 2PDEA 3DV0I 1W4FA 3DVAI 1W4KA 1W85I 1W4IA 1W4HA 1BALA 1W88I 1W4GA 2EQ9C 3RNME 1W4JA 1EBDC 1ZY8K 2WXCA 4QOYE 2BTGA 2BTHA 1ZWVA 2F5ZK 1W4EA 2F60K 2PDDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1W3D A;  2PDE A;  3DV0 I;  1W4F A;  3DVA I;  1W4K A;  1W85 I;  1W4I A;  1W4H A;  1BAL A;  1W88 I;  1W4G A;  2EQ9 C;  3RNM E;  1W4J A;  1EBD C;  1ZY8 K;  2WXC A;  4QOY E;  2BTG A;  2BTH A;  1ZWV A;  2F5Z K;  1W4E A;  2F60 K;  2PDD A; 
#chains in the Genus database with same CATH topology
 1W3D A;  2PDE A;  3DV0 I;  1W4F A;  3DVA I;  1W4K A;  1W85 I;  1W4I A;  1W4H A;  1BAL A;  1W88 I;  1W4G A;  2EQ9 C;  3RNM E;  1W4J A;  1EBD C;  1ZY8 K;  2WXC A;  4QOY E;  2BTG A;  2BTH A;  1ZWV A;  2F5Z K;  1W4E A;  2F60 K;  2PDD A; 
#chains in the Genus database with same CATH homology
 1W3D A;  2PDE A;  3DV0 I;  1W4F A;  3DVA I;  1W4K A;  1W85 I;  1W4I A;  1W4H A;  1BAL A;  1W88 I;  1W4G A;  2EQ9 C;  3RNM E;  1W4J A;  1EBD C;  1ZY8 K;  2WXC A;  4QOY E;  2BTG A;  2BTH A;  1ZWV A;  2F5Z K;  1W4E A;  2F60 K;  2PDD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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