5FWWC

Wnt modulator kremen in complex with dkk1 (crd2) and lrp6 (pe3pe4)
Total Genus 15
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
85
structure length
76
Chain Sequence
KGQEGSVCLRSSDCASGLCCARHFWSKICKPVLKEGQVCTKHRRKGSHGLEIFQRCYCGEGLSCRIQKRLHTCQRH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structure of the Dual-Mode Wnt Regulator Kremen1 and Insight Into Ternary Complex Formation with Lrp6 and Dickkopf
pubmed doi rcsb
molecule keywords LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 6
molecule tags Signaling protein
source organism Homo sapiens
total genus 15
structure length 76
sequence length 85
ec nomenclature
pdb deposition date 2016-02-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.80.10 Mainly Beta Ribbon Lipase, subunit A Lipase, subunit A 5fwwC00
2JTKA 1LPBA 3S2KC 1LPAA 2KRAA 1N8SC 1PCNA 3S8VX 1IMTA 1ETHB 2N8KA 5FWWC 1PCOA
chains in the Genus database with same CATH superfamily
2JTKA 1LPBA 3S2KC 1LPAA 2KRAA 1N8SC 1PCNA 3S8VX 1IMTA 1ETHB 2N8KA 3BT4A 5FWWC 1PCOA
chains in the Genus database with same CATH topology
2JTKA 1LPBA 3S2KC 1LPAA 2KRAA 1N8SC 1PCNA 3S8VX 1IMTA 1ETHB 2N8KA 3BT4A 5FWWC 1PCOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JTK A;  1LPB A;  3S2K C;  1LPA A;  2KRA A;  1N8S C;  1PCN A;  3S8V X;  1IMT A;  1ETH B;  2N8K A;  5FWW C;  1PCO A; 
#chains in the Genus database with same CATH topology
 2JTK A;  1LPB A;  3S2K C;  1LPA A;  2KRA A;  1N8S C;  1PCN A;  3S8V X;  1IMT A;  1ETH B;  2N8K A;  3BT4 A;  5FWW C;  1PCO A; 
#chains in the Genus database with same CATH homology
 2JTK A;  1LPB A;  3S2K C;  1LPA A;  2KRA A;  1N8S C;  1PCN A;  3S8V X;  1IMT A;  1ETH B;  2N8K A;  3BT4 A;  5FWW C;  1PCO A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...