5FWWC

Wnt modulator kremen in complex with dkk1 (crd2) and lrp6 (pe3pe4)
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
85
structure length
76
Chain Sequence
KGQEGSVCLRSSDCASGLCCARHFWSKICKPVLKEGQVCTKHRRKGSHGLEIFQRCYCGEGLSCRIQKRLHTCQRH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the Dual-Mode Wnt Regulator Kremen1 and Insight Into Ternary Complex Formation with Lrp6 and Dickkopf
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 6
total genus 15
structure length 76
sequence length 85
ec nomenclature
pdb deposition date 2016-02-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.80.10 Mainly Beta Ribbon Lipase, subunit A Lipase, subunit A 5fwwC00
1PCNA 1PCOA 1LPAA 2JTKA 1N8SC 5FWWC 2N8KA 3S2KC 2KRAA 1IMTA 3S8VX 1ETHB 1LPBA
chains in the Genus database with same CATH superfamily
1PCNA 1PCOA 1LPAA 2JTKA 3BT4A 1N8SC 5FWWC 2N8KA 3S2KC 2KRAA 1IMTA 3S8VX 1ETHB 1LPBA
chains in the Genus database with same CATH topology
1PCNA 1PCOA 1LPAA 2JTKA 3BT4A 1N8SC 5FWWC 2N8KA 3S2KC 2KRAA 1IMTA 3S8VX 1ETHB 1LPBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PCN A;  1PCO A;  1LPA A;  2JTK A;  1N8S C;  5FWW C;  2N8K A;  3S2K C;  2KRA A;  1IMT A;  3S8V X;  1ETH B;  1LPB A; 
#chains in the Genus database with same CATH topology
 1PCN A;  1PCO A;  1LPA A;  2JTK A;  3BT4 A;  1N8S C;  5FWW C;  2N8K A;  3S2K C;  2KRA A;  1IMT A;  3S8V X;  1ETH B;  1LPB A; 
#chains in the Genus database with same CATH homology
 1PCN A;  1PCO A;  1LPA A;  2JTK A;  3BT4 A;  1N8S C;  5FWW C;  2N8K A;  3S2K C;  2KRA A;  1IMT A;  3S8V X;  1ETH B;  1LPB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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