The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
277
|
sequence length |
738
|
structure length |
738
|
Chain Sequence |
MNQNLLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELRSHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPALYDHVVKMVEMGKYDNHLLEDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLYILVAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTPTRQFSSCVLIECGDSLDSINATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMDYGVQINKLMYTRLLKGEDITLFSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQRVKAVELFSLMMQERASTGRIYIQNVDHCNTHSPFDPAIAPVRQSNLCLQIALPTKPLNDVNDENGEIALCTLSAFNLGAINNLDELEELAILAVRALDALLDYQDYPIPAAKRGAMGRRTLGIGVINFAYYLAKHGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACPWFNETTYAKGILPIDTYKKDLDTIANEPLHYDWEALRESIKTHGLRNSTLSALMPSETSSQISNATNGIEPPRGYVSIKASKDGILRQVVPDYEHLHDAYELLWEMPGNDGYLQLVGIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKTLYYQNTRDGA
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
A new mechanism-based radical intermediate in a mutant R1 protein affecting the catalytically essential Glu441 in Escherichia coli ribonucleotide reductase.
pubmed doi rcsb |
| molecule keywords |
RIBONUCLEOTIDE REDUCTASE R1 PROTEIN
|
| molecule tags |
Complex (oxidoreductase/peptide)
|
| source organism |
Escherichia coli
|
| total genus |
277
|
| structure length |
738
|
| sequence length |
738
|
| chains with identical sequence |
B, C
|
| ec nomenclature |
ec
1.17.4.1: Ribonucleoside-diphosphate reductase. |
| pdb deposition date | 1997-09-17 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00317 | Ribonuc_red_lgN | Ribonucleotide reductase, all-alpha domain |
| A | PF02867 | Ribonuc_red_lgC | Ribonucleotide reductase, barrel domain |
| A | PF03477 | ATP-cone | ATP cone domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | Alpha-Beta Barrel | Anaerobic Ribonucleotide-triphosphate Reductase Large Chain | Anaerobic Ribonucleotide-triphosphate Reductase Large Chain |
#chains in the Genus database with same CATH superfamily 2CVV A; 1PEM A; 1XJG A; 2HA9 A; 4X3V A; 3K8T A; 5CNS A; 5CNU A; 2EUD A; 4MTJ A; 1QHM A; 2XAV A; 2XAX A; 1L1L A; 1PEU A; 1CM5 A; 3TB9 A; 2CVT A; 1XJN A; 2ZLF A; 6R1R A; 1PEO A; 3O0N A; 1H7B A; 3HNC A; 1XJF A; 2XAP A; 1XJK A; 2CVW A; 1R8W A; 4R1R A; 1H79 A; 3TBA A; 2R1R A; 2YAJ A; 5CNV A; 1MZO A; 2CVS A; 1HK8 A; 2XAZ A; 2XO5 A; 3HNF A; 1XJM A; 5CNT A; 3HND A; 1ZYZ A; 3HNE A; 3S8B A; 1R9D A; 1H18 A; 2XAW A; 3O0Q A; 2CVX A; 7R1R A; 2XAY A; 1RLR A; 1H17 A; 1R1R A; 2XO4 A; 2CVY A; 3S87 A; 2ZLG A; 3S8C A; 1XJJ A; 1PEQ A; 2CVU A; 2F3O A; 1XJE A; 3S8A A; 2BQ1 E; 3R1R A; 1H78 A; 1H7A A; 4ERM A; 1ZZD A; 5R1R A; 1H16 A; 2X0X A; 3O0O A; 3PFL A; 2PFL A; 2Y8N A; 2WGH A; 3RSR A; 2XAK A; #chains in the Genus database with same CATH topology 2CVV A; 1PEM A; 1XJG A; 2HA9 A; 4X3V A; 3K8T A; 5CNS A; 5CNU A; 2EUD A; 5A0U A; 5FAW A; 4MTJ A; 1QHM A; 2XAV A; 2XAX A; 1L1L A; 1PEU A; 1CM5 A; 3TB9 A; 2CVT A; 1XJN A; 2ZLF A; 6R1R A; 1PEO A; 3O0N A; 1H7B A; 3HNC A; 5FAV A; 1XJF A; 2XAP A; 1XJK A; 2CVW A; 1R8W A; 4R1R A; 1H79 A; 3TBA A; 2R1R A; 2YAJ A; 5CNV A; 1MZO A; 2CVS A; 1HK8 A; 2XAZ A; 2XO5 A; 3HNF A; 1XJM A; 5CNT A; 3HND A; 5A0Z A; 1ZYZ A; 3HNE A; 3S8B A; 1R9D A; 1H18 A; 2XAW A; 3O0Q A; 2CVX A; 7R1R A; 2XAY A; 1RLR A; 1H17 A; 1R1R A; 2XO4 A; 5FAU A; 2CVY A; 3S87 A; 2ZLG A; 3S8C A; 1XJJ A; 1PEQ A; 2CVU A; 2F3O A; 1XJE A; 3S8A A; 2BQ1 E; 3R1R A; 1H78 A; 1H7A A; 5FAY A; 4ERM A; 1ZZD A; 5R1R A; 1H16 A; 2X0X A; 3O0O A; 3PFL A; 2PFL A; 5KDP A; 2Y8N A; 2WGH A; 3RSR A; 2XAK A; #chains in the Genus database with same CATH homology 2CVV A; 1PEM A; 1XJG A; 2HA9 A; 4X3V A; 3K8T A; 5CNS A; 5CNU A; 2EUD A; 5A0U A; 5FAW A; 4MTJ A; 1QHM A; 2XAV A; 2XAX A; 1L1L A; 1PEU A; 1CM5 A; 3TB9 A; 2CVT A; 1XJN A; 2ZLF A; 6R1R A; 1PEO A; 3O0N A; 1H7B A; 3HNC A; 5FAV A; 1XJF A; 2XAP A; 1XJK A; 2CVW A; 1R8W A; 4R1R A; 1H79 A; 3TBA A; 2R1R A; 2YAJ A; 5CNV A; 1MZO A; 2CVS A; 1HK8 A; 2XAZ A; 2XO5 A; 3HNF A; 1XJM A; 5CNT A; 3HND A; 5A0Z A; 1ZYZ A; 3HNE A; 3S8B A; 1R9D A; 1H18 A; 2XAW A; 3O0Q A; 2CVX A; 7R1R A; 2XAY A; 1RLR A; 1H17 A; 1R1R A; 2XO4 A; 5FAU A; 2CVY A; 3S87 A; 2ZLG A; 3S8C A; 1XJJ A; 1PEQ A; 2CVU A; 2F3O A; 1XJE A; 3S8A A; 2BQ1 E; 3R1R A; 1H78 A; 1H7A A; 5FAY A; 4ERM A; 1ZZD A; 5R1R A; 1H16 A; 2X0X A; 3O0O A; 3PFL A; 2PFL A; 5KDP A; 2Y8N A; 2WGH A; 3RSR A; 2XAK A;
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