1AM4A

Complex between cdc42hs.gmppnp and p50 rhogap (h. sapiens)
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
199
structure length
199
Chain Sequence
PRPPLPNQQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Complex (gtpase-activating/gtp-binding)
molecule keywords P50-RHOGAP
publication title Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP.
pubmed doi rcsb
source organism Homo sapiens
total genus 48
structure length 199
sequence length 199
chains with identical sequence B, C
ec nomenclature
pdb deposition date 1997-06-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 1am4A00
2EE4A 1XA6A 1GRNB 3KUQA 3FK2A 1TX4A 3WPQA 3CXLA 1OW3A 2MBGA 2XS6A 3WPSA 2QV2A 2NGRB 3MSXB 5JCPA 5IRCA 1RGPA 1PBWA 1F7CA 5HPYA 3EAPA 5C5SA 3BYIA 5JD0A 2OVJA 3IUGA 2EE5A 1AM4A 2OSAA 3QISA 5C2JA 3W6RA
chains in the Genus database with same CATH superfamily
2EE4A 1XA6A 1GRNB 3KUQA 3FK2A 1TX4A 3WPQA 3CXLA 1OW3A 2MBGA 2XS6A 3WPSA 2QV2A 2NGRB 3MSXB 5JCPA 5IRCA 1RGPA 1PBWA 1F7CA 5HPYA 3EAPA 5C5SA 3BYIA 5JD0A 2OVJA 3IUGA 2EE5A 1AM4A 2OSAA 3QISA 5C2JA 3W6RA
chains in the Genus database with same CATH topology
2EE4A 1XA6A 1GRNB 3KUQA 3FK2A 1TX4A 3WPQA 3CXLA 1OW3A 2MBGA 2XS6A 3WPSA 2QV2A 2NGRB 3MSXB 5JCPA 5IRCA 1RGPA 1PBWA 1F7CA 5HPYA 3EAPA 5C5SA 3BYIA 5JD0A 2OVJA 3IUGA 2EE5A 1AM4A 2OSAA 3QISA 5C2JA 3W6RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EE4 A;  1XA6 A;  1GRN B;  3KUQ A;  3FK2 A;  1TX4 A;  3WPQ A;  3CXL A;  1OW3 A;  2MBG A;  2XS6 A;  3WPS A;  2QV2 A;  2NGR B;  3MSX B;  5JCP A;  5IRC A;  1RGP A;  1PBW A;  1F7C A;  5HPY A;  3EAP A;  5C5S A;  3BYI A;  5JD0 A;  2OVJ A;  3IUG A;  2EE5 A;  1AM4 A;  2OSA A;  3QIS A;  5C2J A;  3W6R A; 
#chains in the Genus database with same CATH topology
 2EE4 A;  1XA6 A;  1GRN B;  3KUQ A;  3FK2 A;  1TX4 A;  3WPQ A;  3CXL A;  1OW3 A;  2MBG A;  2XS6 A;  3WPS A;  2QV2 A;  2NGR B;  3MSX B;  5JCP A;  5IRC A;  1RGP A;  1PBW A;  1F7C A;  5HPY A;  3EAP A;  5C5S A;  3BYI A;  5JD0 A;  2OVJ A;  3IUG A;  2EE5 A;  1AM4 A;  2OSA A;  3QIS A;  5C2J A;  3W6R A; 
#chains in the Genus database with same CATH homology
 2EE4 A;  1XA6 A;  1GRN B;  3KUQ A;  3FK2 A;  1TX4 A;  3WPQ A;  3CXL A;  1OW3 A;  2MBG A;  2XS6 A;  3WPS A;  2QV2 A;  2NGR B;  3MSX B;  5JCP A;  5IRC A;  1RGP A;  1PBW A;  1F7C A;  5HPY A;  3EAP A;  5C5S A;  3BYI A;  5JD0 A;  2OVJ A;  3IUG A;  2EE5 A;  1AM4 A;  2OSA A;  3QIS A;  5C2J A;  3W6R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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