5C2JA

Complex structure of the gap domain of mgcracgap and cdc42
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
201
structure length
201
Chain Sequence
IGEGMLADFVSQTSPMIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICSLLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHLQRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMSQDIKRQPKVVERLLSLPLEYWSQFMMVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase activator/signaling protein
molecule keywords Rac GTPase-activating protein 1
publication title Structural basis of G-protein target alternation of MgcRacGAP by phospholylation
rcsb
source organism Homo sapiens
total genus 67
structure length 201
sequence length 201
ec nomenclature
pdb deposition date 2015-06-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 5c2jA00
1TX4A 2OSAA 5C2JA 1GRNB 2XS6A 3MSXB 3IUGA 1OW3A 2QV2A 3CXLA 1XA6A 2MBGA 5IRCA 5HPYA 5JCPA 3WPSA 5JD0A 2EE4A 3W6RA 2OVJA 1AM4A 1PBWA 3KUQA 2NGRB 1RGPA 3QISA 5C5SA 1F7CA 3BYIA 3EAPA 3WPQA 2EE5A 3FK2A
chains in the Genus database with same CATH superfamily
1TX4A 2OSAA 5C2JA 1GRNB 2XS6A 3MSXB 3IUGA 1OW3A 2QV2A 3CXLA 1XA6A 2MBGA 5IRCA 5HPYA 5JCPA 3WPSA 5JD0A 2EE4A 3W6RA 2OVJA 1AM4A 1PBWA 3KUQA 2NGRB 1RGPA 3QISA 5C5SA 1F7CA 3BYIA 3EAPA 3WPQA 2EE5A 3FK2A
chains in the Genus database with same CATH topology
1TX4A 2OSAA 5C2JA 1GRNB 2XS6A 3MSXB 3IUGA 1OW3A 2QV2A 3CXLA 1XA6A 2MBGA 5IRCA 5HPYA 5JCPA 3WPSA 5JD0A 2EE4A 3W6RA 2OVJA 1AM4A 1PBWA 3KUQA 2NGRB 1RGPA 3QISA 5C5SA 1F7CA 3BYIA 3EAPA 3WPQA 2EE5A 3FK2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TX4 A;  2OSA A;  5C2J A;  1GRN B;  2XS6 A;  3MSX B;  3IUG A;  1OW3 A;  2QV2 A;  3CXL A;  1XA6 A;  2MBG A;  5IRC A;  5HPY A;  5JCP A;  3WPS A;  5JD0 A;  2EE4 A;  3W6R A;  2OVJ A;  1AM4 A;  1PBW A;  3KUQ A;  2NGR B;  1RGP A;  3QIS A;  5C5S A;  1F7C A;  3BYI A;  3EAP A;  3WPQ A;  2EE5 A;  3FK2 A; 
#chains in the Genus database with same CATH topology
 1TX4 A;  2OSA A;  5C2J A;  1GRN B;  2XS6 A;  3MSX B;  3IUG A;  1OW3 A;  2QV2 A;  3CXL A;  1XA6 A;  2MBG A;  5IRC A;  5HPY A;  5JCP A;  3WPS A;  5JD0 A;  2EE4 A;  3W6R A;  2OVJ A;  1AM4 A;  1PBW A;  3KUQ A;  2NGR B;  1RGP A;  3QIS A;  5C5S A;  1F7C A;  3BYI A;  3EAP A;  3WPQ A;  2EE5 A;  3FK2 A; 
#chains in the Genus database with same CATH homology
 1TX4 A;  2OSA A;  5C2J A;  1GRN B;  2XS6 A;  3MSX B;  3IUG A;  1OW3 A;  2QV2 A;  3CXL A;  1XA6 A;  2MBG A;  5IRC A;  5HPY A;  5JCP A;  3WPS A;  5JD0 A;  2EE4 A;  3W6R A;  2OVJ A;  1AM4 A;  1PBW A;  3KUQ A;  2NGR B;  1RGP A;  3QIS A;  5C5S A;  1F7C A;  3BYI A;  3EAP A;  3WPQ A;  2EE5 A;  3FK2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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