1PBWA

Structure of bcr-homology (bh) domain
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
184
structure length
184
Chain Sequence
LPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQLLDCDTPSVDLEMIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIKVIEILISTEW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Phosphotransferase
molecule keywords PHOSPHATIDYLINOSITOL 3-KINASE
publication title Crystal structure of the breakpoint cluster region-homology domain from phosphoinositide 3-kinase p85 alpha subunit.
pubmed doi rcsb
source organism Homo sapiens
total genus 67
structure length 184
sequence length 184
chains with identical sequence B
ec nomenclature
pdb deposition date 1996-10-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 1pbwA00
3W6RA 5C5SA 2EE4A 1GRNB 1TX4A 3QISA 3MSXB 2OVJA 2XS6A 1OW3A 3WPSA 5JD0A 2MBGA 1RGPA 3KUQA 5C2JA 2EE5A 2QV2A 1AM4A 2OSAA 3BYIA 3EAPA 2NGRB 1F7CA 3WPQA 3CXLA 5IRCA 5HPYA 3FK2A 5JCPA 1PBWA 3IUGA 1XA6A
chains in the Genus database with same CATH superfamily
3W6RA 5C5SA 2EE4A 1GRNB 1TX4A 3QISA 3MSXB 2OVJA 2XS6A 1OW3A 3WPSA 5JD0A 2MBGA 1RGPA 3KUQA 5C2JA 2EE5A 2QV2A 1AM4A 2OSAA 3BYIA 3EAPA 2NGRB 1F7CA 3WPQA 3CXLA 5IRCA 5HPYA 3FK2A 5JCPA 1PBWA 3IUGA 1XA6A
chains in the Genus database with same CATH topology
3W6RA 5C5SA 2EE4A 1GRNB 1TX4A 3QISA 3MSXB 2OVJA 2XS6A 1OW3A 3WPSA 5JD0A 2MBGA 1RGPA 3KUQA 5C2JA 2EE5A 2QV2A 1AM4A 2OSAA 3BYIA 3EAPA 2NGRB 1F7CA 3WPQA 3CXLA 5IRCA 5HPYA 3FK2A 5JCPA 1PBWA 3IUGA 1XA6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3W6R A;  5C5S A;  2EE4 A;  1GRN B;  1TX4 A;  3QIS A;  3MSX B;  2OVJ A;  2XS6 A;  1OW3 A;  3WPS A;  5JD0 A;  2MBG A;  1RGP A;  3KUQ A;  5C2J A;  2EE5 A;  2QV2 A;  1AM4 A;  2OSA A;  3BYI A;  3EAP A;  2NGR B;  1F7C A;  3WPQ A;  3CXL A;  5IRC A;  5HPY A;  3FK2 A;  5JCP A;  1PBW A;  3IUG A;  1XA6 A; 
#chains in the Genus database with same CATH topology
 3W6R A;  5C5S A;  2EE4 A;  1GRN B;  1TX4 A;  3QIS A;  3MSX B;  2OVJ A;  2XS6 A;  1OW3 A;  3WPS A;  5JD0 A;  2MBG A;  1RGP A;  3KUQ A;  5C2J A;  2EE5 A;  2QV2 A;  1AM4 A;  2OSA A;  3BYI A;  3EAP A;  2NGR B;  1F7C A;  3WPQ A;  3CXL A;  5IRC A;  5HPY A;  3FK2 A;  5JCP A;  1PBW A;  3IUG A;  1XA6 A; 
#chains in the Genus database with same CATH homology
 3W6R A;  5C5S A;  2EE4 A;  1GRN B;  1TX4 A;  3QIS A;  3MSX B;  2OVJ A;  2XS6 A;  1OW3 A;  3WPS A;  5JD0 A;  2MBG A;  1RGP A;  3KUQ A;  5C2J A;  2EE5 A;  2QV2 A;  1AM4 A;  2OSA A;  3BYI A;  3EAP A;  2NGR B;  1F7C A;  3WPQ A;  3CXL A;  5IRC A;  5HPY A;  3FK2 A;  5JCP A;  1PBW A;  3IUG A;  1XA6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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