2EE4A

Solution structure of the rhogap domain from human rho gtpase activating protein 5 variant
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
209
structure length
209
Chain Sequence
GSSGSSGWESNYFGMPLQDLVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVETFIQQCQFFFYNGEIVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords Rho GTPase activating protein 5 variant
publication title Solution structure of the RhoGAP domain from human Rho GTPase activating protein 5 variant
rcsb
source organism Homo sapiens
total genus 45
structure length 209
sequence length 209
ec nomenclature ec 3.6.5.2: Small monomeric GTPase.
pdb deposition date 2007-02-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 2ee4A01
3CXLA 3W6RA 1PBWA 3KUQA 2QV2A 3IUGA 3QISA 2EE5A 5IRCA 3BYIA 3WPQA 3WPSA 5C2JA 1XA6A 5C5SA 1AM4A 3EAPA 3FK2A 3MSXB 2MBGA 1OW3A 2XS6A 1F7CA 5JD0A 1RGPA 5JCPA 5HPYA 1GRNB 1TX4A 2OVJA 2EE4A 2OSAA 2NGRB
chains in the Genus database with same CATH superfamily
3CXLA 3W6RA 1PBWA 3KUQA 2QV2A 3IUGA 3QISA 2EE5A 5IRCA 3BYIA 3WPQA 3WPSA 5C2JA 1XA6A 5C5SA 1AM4A 3EAPA 3FK2A 3MSXB 2MBGA 1OW3A 2XS6A 1F7CA 5JD0A 1RGPA 5JCPA 5HPYA 1GRNB 1TX4A 2OVJA 2EE4A 2OSAA 2NGRB
chains in the Genus database with same CATH topology
3CXLA 3W6RA 1PBWA 3KUQA 2QV2A 3IUGA 3QISA 2EE5A 5IRCA 3BYIA 3WPQA 3WPSA 5C2JA 1XA6A 5C5SA 1AM4A 3EAPA 3FK2A 3MSXB 2MBGA 1OW3A 2XS6A 1F7CA 5JD0A 1RGPA 5JCPA 5HPYA 1GRNB 1TX4A 2OVJA 2EE4A 2OSAA 2NGRB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CXL A;  3W6R A;  1PBW A;  3KUQ A;  2QV2 A;  3IUG A;  3QIS A;  2EE5 A;  5IRC A;  3BYI A;  3WPQ A;  3WPS A;  5C2J A;  1XA6 A;  5C5S A;  1AM4 A;  3EAP A;  3FK2 A;  3MSX B;  2MBG A;  1OW3 A;  2XS6 A;  1F7C A;  5JD0 A;  1RGP A;  5JCP A;  5HPY A;  1GRN B;  1TX4 A;  2OVJ A;  2EE4 A;  2OSA A;  2NGR B; 
#chains in the Genus database with same CATH topology
 3CXL A;  3W6R A;  1PBW A;  3KUQ A;  2QV2 A;  3IUG A;  3QIS A;  2EE5 A;  5IRC A;  3BYI A;  3WPQ A;  3WPS A;  5C2J A;  1XA6 A;  5C5S A;  1AM4 A;  3EAP A;  3FK2 A;  3MSX B;  2MBG A;  1OW3 A;  2XS6 A;  1F7C A;  5JD0 A;  1RGP A;  5JCP A;  5HPY A;  1GRN B;  1TX4 A;  2OVJ A;  2EE4 A;  2OSA A;  2NGR B; 
#chains in the Genus database with same CATH homology
 3CXL A;  3W6R A;  1PBW A;  3KUQ A;  2QV2 A;  3IUG A;  3QIS A;  2EE5 A;  5IRC A;  3BYI A;  3WPQ A;  3WPS A;  5C2J A;  1XA6 A;  5C5S A;  1AM4 A;  3EAP A;  3FK2 A;  3MSX B;  2MBG A;  1OW3 A;  2XS6 A;  1F7C A;  5JD0 A;  1RGP A;  5JCP A;  5HPY A;  1GRN B;  1TX4 A;  2OVJ A;  2EE4 A;  2OSA A;  2NGR B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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