1RGPA

Gtpase-activation domain from rhogap
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
199
structure length
189
Chain Sequence
PRPPLPNQQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWINPINTFTKFLLDHQGELF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags G-protein
molecule keywords RHOGAP
publication title The structure of the GTPase-activating domain from p50rhoGAP.
pubmed doi rcsb
source organism Homo sapiens
total genus 61
structure length 189
sequence length 199
ec nomenclature
pdb deposition date 1996-12-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 1rgpA00
3EAPA 2OSAA 5JCPA 1RGPA 2OVJA 2XS6A 5IRCA 3BYIA 1F7CA 5JD0A 1OW3A 3FK2A 1GRNB 3W6RA 5C2JA 2MBGA 1PBWA 3MSXB 5C5SA 3IUGA 5HPYA 1AM4A 3WPSA 2EE4A 1TX4A 3KUQA 2QV2A 3WPQA 3CXLA 1XA6A 2NGRB 3QISA 2EE5A
chains in the Genus database with same CATH superfamily
3EAPA 2OSAA 5JCPA 1RGPA 2OVJA 2XS6A 5IRCA 3BYIA 1F7CA 5JD0A 1OW3A 3FK2A 1GRNB 3W6RA 5C2JA 2MBGA 1PBWA 3MSXB 5C5SA 3IUGA 5HPYA 1AM4A 3WPSA 2EE4A 1TX4A 3KUQA 2QV2A 3WPQA 3CXLA 1XA6A 2NGRB 3QISA 2EE5A
chains in the Genus database with same CATH topology
3EAPA 2OSAA 5JCPA 1RGPA 2OVJA 2XS6A 5IRCA 3BYIA 1F7CA 5JD0A 1OW3A 3FK2A 1GRNB 3W6RA 5C2JA 2MBGA 1PBWA 3MSXB 5C5SA 3IUGA 5HPYA 1AM4A 3WPSA 2EE4A 1TX4A 3KUQA 2QV2A 3WPQA 3CXLA 1XA6A 2NGRB 3QISA 2EE5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EAP A;  2OSA A;  5JCP A;  1RGP A;  2OVJ A;  2XS6 A;  5IRC A;  3BYI A;  1F7C A;  5JD0 A;  1OW3 A;  3FK2 A;  1GRN B;  3W6R A;  5C2J A;  2MBG A;  1PBW A;  3MSX B;  5C5S A;  3IUG A;  5HPY A;  1AM4 A;  3WPS A;  2EE4 A;  1TX4 A;  3KUQ A;  2QV2 A;  3WPQ A;  3CXL A;  1XA6 A;  2NGR B;  3QIS A;  2EE5 A; 
#chains in the Genus database with same CATH topology
 3EAP A;  2OSA A;  5JCP A;  1RGP A;  2OVJ A;  2XS6 A;  5IRC A;  3BYI A;  1F7C A;  5JD0 A;  1OW3 A;  3FK2 A;  1GRN B;  3W6R A;  5C2J A;  2MBG A;  1PBW A;  3MSX B;  5C5S A;  3IUG A;  5HPY A;  1AM4 A;  3WPS A;  2EE4 A;  1TX4 A;  3KUQ A;  2QV2 A;  3WPQ A;  3CXL A;  1XA6 A;  2NGR B;  3QIS A;  2EE5 A; 
#chains in the Genus database with same CATH homology
 3EAP A;  2OSA A;  5JCP A;  1RGP A;  2OVJ A;  2XS6 A;  5IRC A;  3BYI A;  1F7C A;  5JD0 A;  1OW3 A;  3FK2 A;  1GRN B;  3W6R A;  5C2J A;  2MBG A;  1PBW A;  3MSX B;  5C5S A;  3IUG A;  5HPY A;  1AM4 A;  3WPS A;  2EE4 A;  1TX4 A;  3KUQ A;  2QV2 A;  3WPQ A;  3CXL A;  1XA6 A;  2NGR B;  3QIS A;  2EE5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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