5HPYA

Crystal structure of rhoa.gdp.mgf3-in complex with human myosin 9b rhogap domain
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
203
structure length
192
Chain Sequence
GHFGVCVSVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLENFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCSDPLTSMKDVLKITTCVEMLIKEQMRKYKVKMEEISQL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Gene regulation/signaling protein
molecule keywords Unconventional myosin-IXb
publication title Noncanonical Myo9b-RhoGAP Accelerates RhoA GTP Hydrolysis by a Dual-Arginine-Finger Mechanism
pubmed doi rcsb
source organism Homo sapiens
total genus 72
structure length 192
sequence length 203
chains with identical sequence D
ec nomenclature
pdb deposition date 2016-01-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 5hpyA00
2QV2A 3QISA 1XA6A 2MBGA 3WPQA 5HPYA 3WPSA 3FK2A 5JD0A 3IUGA 1GRNB 2NGRB 3KUQA 2EE4A 1OW3A 1RGPA 5JCPA 3W6RA 5IRCA 5C2JA 2OVJA 3EAPA 1F7CA 1PBWA 1AM4A 5C5SA 2EE5A 3BYIA 1TX4A 3MSXB 3CXLA 2OSAA 2XS6A
chains in the Genus database with same CATH superfamily
2QV2A 3QISA 1XA6A 2MBGA 3WPQA 5HPYA 3WPSA 3FK2A 5JD0A 3IUGA 1GRNB 2NGRB 3KUQA 2EE4A 1OW3A 1RGPA 5JCPA 3W6RA 5IRCA 5C2JA 2OVJA 3EAPA 1F7CA 1PBWA 1AM4A 5C5SA 2EE5A 3BYIA 1TX4A 3MSXB 3CXLA 2OSAA 2XS6A
chains in the Genus database with same CATH topology
2QV2A 3QISA 1XA6A 2MBGA 3WPQA 5HPYA 3WPSA 3FK2A 5JD0A 3IUGA 1GRNB 2NGRB 3KUQA 2EE4A 1OW3A 1RGPA 5JCPA 3W6RA 5IRCA 5C2JA 2OVJA 3EAPA 1F7CA 1PBWA 1AM4A 5C5SA 2EE5A 3BYIA 1TX4A 3MSXB 3CXLA 2OSAA 2XS6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QV2 A;  3QIS A;  1XA6 A;  2MBG A;  3WPQ A;  5HPY A;  3WPS A;  3FK2 A;  5JD0 A;  3IUG A;  1GRN B;  2NGR B;  3KUQ A;  2EE4 A;  1OW3 A;  1RGP A;  5JCP A;  3W6R A;  5IRC A;  5C2J A;  2OVJ A;  3EAP A;  1F7C A;  1PBW A;  1AM4 A;  5C5S A;  2EE5 A;  3BYI A;  1TX4 A;  3MSX B;  3CXL A;  2OSA A;  2XS6 A; 
#chains in the Genus database with same CATH topology
 2QV2 A;  3QIS A;  1XA6 A;  2MBG A;  3WPQ A;  5HPY A;  3WPS A;  3FK2 A;  5JD0 A;  3IUG A;  1GRN B;  2NGR B;  3KUQ A;  2EE4 A;  1OW3 A;  1RGP A;  5JCP A;  3W6R A;  5IRC A;  5C2J A;  2OVJ A;  3EAP A;  1F7C A;  1PBW A;  1AM4 A;  5C5S A;  2EE5 A;  3BYI A;  1TX4 A;  3MSX B;  3CXL A;  2OSA A;  2XS6 A; 
#chains in the Genus database with same CATH homology
 2QV2 A;  3QIS A;  1XA6 A;  2MBG A;  3WPQ A;  5HPY A;  3WPS A;  3FK2 A;  5JD0 A;  3IUG A;  1GRN B;  2NGR B;  3KUQ A;  2EE4 A;  1OW3 A;  1RGP A;  5JCP A;  3W6R A;  5IRC A;  5C2J A;  2OVJ A;  3EAP A;  1F7C A;  1PBW A;  1AM4 A;  5C5S A;  2EE5 A;  3BYI A;  1TX4 A;  3MSX B;  3CXL A;  2OSA A;  2XS6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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