The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
70
|
sequence length |
335
|
structure length |
303
|
Chain Sequence |
LDKVNLGGELSGSNMYVYNGFVIVSGDKRSPEILGYSTSGSFDVNGKENIASFMESYVEQIKENKKLPVVKSLLDSKGIHYNQGNPYNLLTPVIEKVKPGEQSFVGQHAATGSVATATAQIMKYHNYPNKGLKDYTYTLSSNNPYFNHPKNLFAAISTRQYNWNNILPTYSGRESNVQKMAISELMADVGISVDMDYGPSSGSAGSSRVQRALKENFGYNQSVHQINRGDFSKQDWEAQIDKELSQNQPVYYQGVGKVGGHAFVIDGADGRNFYHVNWGWGGVSDGFFRLDALYQSAVVGIKP
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| molecule tags |
Toxin
|
| molecule keywords |
PYROGENIC EXOTOXIN B ZYMOGEN
|
| publication title |
Crystal structure of the zymogen form of the group A Streptococcus virulence factor SpeB: an integrin-binding cysteine protease.
pubmed doi rcsb |
| source organism |
Streptococcus pyogenes
|
| total genus |
70
|
| structure length |
303
|
| sequence length |
335
|
| chains with identical sequence |
B, C, D
|
| ec nomenclature |
ec
3.4.22.10: Streptopain. |
| pdb deposition date | 1999-12-07 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF01640 | Peptidase_C10 | Peptidase C10 family |
| A | PF13734 | Inhibitor_I69 | Spi protease inhibitor |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | 2-Layer Sandwich | Protein Binding, DinI Protein; Chain A | Protein Binding, DinI Protein; Chain A | ||
| Alpha Beta | Alpha-Beta Complex | Cathepsin B; Chain A | Cathepsin B; Chain A |
#chains in the Genus database with same CATH superfamily 1DKI A; 4RKX A; 2UZJ A; 3BBA A; 4D8E A; 4D8B A; 3BB7 A; 1PVJ A; 2JTC A; 4D8I A; #chains in the Genus database with same CATH topology 1XKG A; 1PPN A; 2UZJ A; 2CB5 A; 4BOP A; 1AYW A; 1EF7 A; 4REZ A; 4PT5 A; 5CVM A; 4CDE B; 3H8C A; 2P7U A; 1STF E; 2AUX A; 4WA6 A; 3CBJ A; 3PT2 A; 3ZNH A; 4YYQ A; 1QOL A; 3OQC A; 3B21 A; 2NQD B; 3IV2 A; 2XU1 A; 4QRV A; 2DCD A; 3HWN A; 1AIM A; 3M99 A; 1Y08 A; 1KHQ A; 4FK5 A; 4N8W A; 3N3G A; 4HWY A; 2ACT A; 1MIR A; 3IFU A; 2IPP B; 3ERV A; 1HUC B; 2BU3 A; 2DCB A; 2XU3 A; 1POP A; 5EGW A; 2P0R A; 4CDC B; 2OUL A; 3PSE A; 1ICF A; 3LXS A; 5CHT A; 3PHU A; 3QT4 A; 4PI3 A; 4EVX A; 3PHX A; 2DC7 A; 1MEM A; 4KQT A; 6PAD A; 1MS6 A; 1GHH A; 1SG2 A; 4BOZ A; 2FUD A; 4YYV A; 2B1N A; 1ATK A; 1KHP A; 4W5B A; 4Q8G A; 5EZS A; 4ZUX U; 4AXM A; 4X6I A; 1JQP A; 3MHS A; 5J94 A; 3BB7 A; 1CS8 A; 2E00 A; 2Y6E A; 2YJ8 A; 3S3R A; 1QXP A; 2F7D A; 2AYO A; 3H6S A; 2H7J A; 1U9W A; 1EWL A; 5EZQ A; 3O65 A; 4XR7 A; 2Z84 A; 2GFO A; 5E6J A; 3F75 A; 5EF4 A; 1ZIV A; 4CDD B; 1PBH A; 1THE A; 2Y5B A; 1CPJ A; 1DF0 A; 1PAD A; 1NB3 A; 3V6C A; 1BGO A; 1Y4H A; 2PNS A; 1KFX L; 2NQA A; 1YVB A; 3IMA A; 4A5U A; 2FO5 A; 1AU4 A; 3H7D A; 4I07 A; 5CVO B; 2HWK A; 4RKX A; 2VHF A; 3KWZ A; 3O1G A; 4XUI A; 5KO3 A; 2PBH A; 3TNX A; 1QMY A; 2JTC A; 2PAD A; 1ZCM A; 1K3B B; 2FQ9 A; 3IEJ A; 2GHU A; 3PBH A; 3LFY A; 1TL9 A; 2FE8 A; 1GLO A; 1O0E A; 3HHI A; 1ME3 A; 4BS5 A; 2YJC A; 3I3T A; 3P5X A; 1PE6 A; 3P5W A; 3W30 A; 2PRE A; 2ATO A; 1UKF A; 2DC6 A; 1YK8 A; 1CV8 A; 1SP4 B; 3MTV A; 4OVZ B; 1CTE A; 4W4U A; 1KXR A; 1M6D A; 2DZZ A; 2R9M A; 1ITO A; 2DJG B; 5FPW A; 3W31 A; 4N4Z A; 3RVV A; 3E1Z B; 2FTD A; 5K16 A; 4OEM A; 4BQV A; 3BC3 A; 4MZO A; 5JA7 A; 1AEC A; 4MSX A; 1U9V A; 2VHS A; 5PAD A; 4QRX A; 8PCH A; 3H89 A; 4QBB A; 1PPO A; 1YK7 A; 2AU1 A; 2FRA A; 3QSD A; 2J7Q A; 4P6E A; 3OVX A; 4RY2 A; 1GMY A; 2DC8 A; 3PRP A; 3GCB A; 1F29 A; 2HH5 A; 1MDW A; 1PVJ A; 2E02 A; 2F1G A; 2E01 A; 5A24 A; 1EWP A; 3BWK A; 1NPZ A; 1EWM A; 3IUT A; 4RF1 A; 2FRQ A; 2JRI A; 3CH3 X; 4MM3 B; 2DOS A; 3BY4 A; 3IHP A; 3D6S A; 4OVZ A; 2DCC A; 3NHE A; 5JH3 A; 4N79 A; 1EWO A; 3WXE A; 4AXL A; 3TRK A; 1BY8 A; 2R6N A; 4BOU A; 1AYV A; 3KFQ A; 3ZUA A; 3U8E A; 1CJL A; 1PIP A; 1CB5 A; 3KW9 A; 1MHW A; 3PHW A; 2OP3 A; 3MTN A; 4YVA A; 4KLB A; 4IP3 A; 2BTW B; 1U2M A; 4K7C A; 1PXV A; 2JQF R; 1CQD A; 1TLO A; 3BCN A; 4W5C A; 1VJV A; 3I06 A; 3KWB X; 2DCA A; 4MZS A; 3WXG A; 2AYN A; 3MP2 A; 1FH0 A; 5CHV A; 1MEG A; 4IUM A; 4QH6 A; 3BBA A; 3TMP A; 1F2A A; 1GEC E; 1NQC A; 2G8E A; 1CSB B; 2O6X A; 4QRG A; 3N4C A; 1YZB A; 3RVX A; 3MOR A; 2BDL A; 1NLJ A; 1YT7 A; 3C0R A; 1S4V A; 3IOQ A; 3KSE A; 2FYE A; 2AGA A; 4GUA A; 4I04 A; 3BPF A; 3RVW A; 1QDQ A; 4CZW A; 2OZ2 A; 1DKI A; 4FJC A; 1PCI A; 5CVN B; 2NQG A; 4D8B A; 3PDF A; 3H8B A; 1A6R A; 4YYR A; 3USV A; 3OF9 A; 4P16 A; 2DC9 A; 3PW3 A; 2P86 A; 2AS8 A; 3KKU A; 3OF8 A; 2AUZ A; 2WBF X; 3HD3 A; 1U9Q X; 2BTW A; 9PAP A; 1F2B A; 4RNA A; 4BOQ A; 3OIS A; 4D8E A; 2E03 A; 4I05 A; 4XZX A; 2B1M A; 4HXD B; 2AIM A; 3C9E A; 3KX1 A; 2YJB A; 3WXF A; 3QJ3 A; 4BSQ A; 4BPV A; 4G54 A; 3K9M A; 2JQG R; 4D8I A; 1TU6 A; 3E9S A; 3MHH A; 3P5U A; 1PPP A; 2AVW A; 4R3D A; 4CDF B; 1U5I A; 3CH2 X; 2BDZ A; 2HD5 A; 3F5V A; 1F2C A; 3B79 A; 3OVZ A; 2ARY A; 2R9O A; 1KFU L; 2R9C A; 2IBI A; 1BQI A; 3K24 A; 1Q6K A; 1ME4 A; 1CVZ A; 2J7Q C; 2G6D A; 1BP4 A; 1AYU A; 3DF0 A; 1GCB A; 4PP1 A; 3PNR A; 2R9N A; 4P6G A; 4DMY A; 4OEL A; 3HHA A; 1U9X A; 4MI7 A; 3PRM A; 7PCK A; 1AU3 A; 4X6H A; 1AU2 A; 2DJF B; 3CBK A; 3P5V A; 3AI8 A; 3BPM A; 2R9F A; 1SNK A; 1IWD A; 4BOS A; 2G7Y A; 5F02 A; 4YYW A; 3S3Q A; 1X9Y A; 2YJ9 A; 5JZE A; 2HXZ A; 1NB5 A; 4WUR A; 4X6J A; 3V6E A; 4ZTB A; 1YAL A; 2G8J A; 3RNV A; 1PPD A; 4BS6 A; 3MJ5 A; 2NQI A; 3BOW A; 4PAD A; 2YJ2 A; 2C0Y A; 1VSN A; 2HHN A; 1NL6 A; 4RF0 A; 2DZY A; 4YV8 A; 4OW0 A; 4Q8H A; 2XU4 A; 4PP2 E; 4FIP A; 3N3K A; 1AU0 A; 1DEU A; 4DMX A; 4YYS A; 2FT2 A; 4YYU A; 3O0U A; 3K8U A; 4M0W A; 2CIO A; 2XU5 A; #chains in the Genus database with same CATH homology 3BY4 A; 3E9S A; 4OVZ A; 2UZJ A; 4BOP A; 4REZ A; 4PT5 A; 4A5U A; 4R3D A; 3TRK A; 3PT2 A; 3ZNH A; 4BOU A; 2HWK A; 4RKX A; 5KO3 A; 2JTC A; 3B21 A; 3OQC A; 3PHW A; 2J7Q C; 4IP3 A; 2BTW B; 2FE8 A; 4MI7 A; 3PRM A; 3IFU A; 3W30 A; 3MP2 A; 2BU3 A; 1UKF A; 4IUM A; 3BBA A; 3TMP A; 3MTV A; 4OVZ B; 3PSE A; 3PHU A; 1YZB A; 4BOS A; 3W31 A; 4EVX A; 3PHX A; 5JZE A; 3C0R A; 4WUR A; 4ZTB A; 4GUA A; 2AGA A; 4BOZ A; 1DKI A; 3RNV A; 5EZS A; 4D8B A; 3MJ5 A; 2J7Q A; 4P16 A; 3BB7 A; 3PRP A; 4RF0 A; 1PVJ A; 3O65 A; 4OW0 A; 5EZQ A; 2Z84 A; 2BTW A; 5E6J A; 4RNA A; 4BOQ A; 4D8E A; 4XZX A; 4HXD B; 4RF1 A; 4M0W A; 2JRI A; 4MM3 B; 4D8I A; 2DOS A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
