1SG1X

Crystal structure of the receptor-ligand complex between nerve growth factor and the common neurotrophin receptor p75
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
160
structure length
160
Chain Sequence
ETCSTGLYTHSGECCKACNLGEGVAQPCGANQTVCEPCLDNVTFSDVVSATEPCKPCTECLGLQSMSAPCVEADDAVCRCAYGYYQDEETGHCEACSVCEVGSGLVFSCQDKQNTVCEECPEGTYSDEANHVDPCLPCTVCEDTERQLRECTPWADAECE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hormone/growth factor/membrane protein
molecule keywords Beta-nerve growth factor
publication title Structure of nerve growth factor complexed with the shared neurotrophin receptor p75
pubmed doi rcsb
source organism Homo sapiens
total genus 27
structure length 160
sequence length 160
ec nomenclature
pdb deposition date 2004-02-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 1sg1X02
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 1sg1X01
4BK5A 4KGGC 4YN0A 2UWIA 3U3PA 1DU3A 4FHQA 3MBWA 3QD6R 3QO4A 1FT4A 3THMF 3U3SA 2HEVR 5L36B 3WVTA 3U3VA 3MI8D 4I9XC 4N90R 1NCFA 3ALQR 4GIQR 3TJEF 3U3QA 5IHLA 4M4PA 3BUKC 4BK4A 1SG1X 3ME2R 2AW2B 3U3TA 4MXWR 4MSVB 1D0GR 3ME4A 2H9GR 5DMJA 3K51B 3URFZ 1EXTA 2HEYR 4E4DR 3MHDD 5BNQR 2X10A 4M4RA 3X3FA 3QBQB 4KGQC 1ZA3R 3FL7A 4J6GC 4RSUD 1JMAB 5CIRE 4OD2S 1TNRR 1D4VA 3IJ2X
chains in the Genus database with same CATH superfamily
4BK5A 4KGGC 4YN0A 2UWIA 3U3PA 1DU3A 4FHQA 3MBWA 3QD6R 3QO4A 1FT4A 3THMF 3U3SA 2E4VA 2HEVR 5L36B 3WVTA 3U3VA 3MI8D 4I9XC 4N90R 1NCFA 3ALQR 4GIQR 3TJEF 3U3QA 5IHLA 4M4PA 3BUKC 4BK4A 1SG1X 3ME2R 2AW2B 3U3TA 2E4YA 4MSVB 1D0GR 3ME4A 2H9GR 4MXWR 2E4WA 3K51B 5DMJA 1EXTA 2HEYR 3URFZ 4E4DR 3MHDD 5BNQR 2X10A 4M4RA 3X3FA 3QBQB 4KGQC 1ZA3R 3FL7A 4J6GC 2E4XA 4RSUD 1JMAB 2E4UA 5CIRE 4OD2S 1TNRR 1D4VA 2QR6A 3IJ2X
chains in the Genus database with same CATH topology
4BK5A 4KGGC 4YN0A 2UWIA 3U3PA 1DU3A 4FHQA 3MBWA 3QD6R 3QO4A 1FT4A 3THMF 3U3SA 2HEVR 5L36B 3WVTA 3U3VA 3MI8D 4I9XC 4N90R 1NCFA 3ALQR 4GIQR 3TJEF 3U3QA 5IHLA 4M4PA 3BUKC 4BK4A 1SG1X 3ME2R 2AW2B 3U3TA 4MXWR 4MSVB 1D0GR 3ME4A 2H9GR 5DMJA 3K51B 3URFZ 1EXTA 2HEYR 4E4DR 3MHDD 5BNQR 2X10A 4M4RA 3X3FA 3QBQB 4KGQC 1ZA3R 3FL7A 4J6GC 4RSUD 1JMAB 5CIRE 4OD2S 1TNRR 1D4VA 3IJ2X
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BK5 A;  4KGG C;  4YN0 A;  2UWI A;  3U3P A;  1DU3 A;  4FHQ A;  3MBW A;  3QD6 R;  3QO4 A;  1FT4 A;  3THM F;  3U3S A;  2HEV R;  5L36 B;  3WVT A;  3U3V A;  3MI8 D;  4I9X C;  4N90 R;  1NCF A;  3ALQ R;  4GIQ R;  3TJE F;  3U3Q A;  5IHL A;  4M4P A;  3BUK C;  4BK4 A;  1SG1 X;  3ME2 R;  2AW2 B;  3U3T A;  4MXW R;  4MSV B;  1D0G R;  3ME4 A;  2H9G R;  5DMJ A;  3K51 B;  3URF Z;  1EXT A;  2HEY R;  4E4D R;  3MHD D;  5BNQ R;  2X10 A;  4M4R A;  3X3F A;  3QBQ B;  4KGQ C;  1ZA3 R;  3FL7 A;  4J6G C;  4RSU D;  1JMA B;  5CIR E;  4OD2 S;  1TNR R;  1D4V A;  3IJ2 X; 
#chains in the Genus database with same CATH topology
 4BK5 A;  4KGG C;  4YN0 A;  2UWI A;  3U3P A;  1DU3 A;  4FHQ A;  3MBW A;  3QD6 R;  3QO4 A;  1FT4 A;  3THM F;  3U3S A;  2E4V A;  2HEV R;  5L36 B;  3WVT A;  3U3V A;  3MI8 D;  4I9X C;  4N90 R;  1NCF A;  3ALQ R;  4GIQ R;  3TJE F;  3U3Q A;  5IHL A;  4M4P A;  3BUK C;  4BK4 A;  1SG1 X;  3ME2 R;  2AW2 B;  3U3T A;  2E4Y A;  4MSV B;  1D0G R;  3ME4 A;  2H9G R;  4MXW R;  2E4W A;  3K51 B;  5DMJ A;  1EXT A;  2HEY R;  3URF Z;  4E4D R;  3MHD D;  5BNQ R;  2X10 A;  4M4R A;  3X3F A;  3QBQ B;  4KGQ C;  1ZA3 R;  3FL7 A;  4J6G C;  2E4X A;  4RSU D;  1JMA B;  2E4U A;  5CIR E;  4OD2 S;  1TNR R;  1D4V A;  2QR6 A;  3IJ2 X; 
#chains in the Genus database with same CATH homology
 4BK5 A;  4KGG C;  4YN0 A;  2UWI A;  3U3P A;  1DU3 A;  4FHQ A;  3MBW A;  3QD6 R;  3QO4 A;  1FT4 A;  3THM F;  3U3S A;  2HEV R;  5L36 B;  3WVT A;  3U3V A;  3MI8 D;  4I9X C;  4N90 R;  1NCF A;  3ALQ R;  4GIQ R;  3TJE F;  3U3Q A;  5IHL A;  4M4P A;  3BUK C;  4BK4 A;  1SG1 X;  3ME2 R;  2AW2 B;  3U3T A;  4MXW R;  4MSV B;  1D0G R;  3ME4 A;  2H9G R;  5DMJ A;  3K51 B;  3URF Z;  1EXT A;  2HEY R;  4E4D R;  3MHD D;  5BNQ R;  2X10 A;  4M4R A;  3X3F A;  3QBQ B;  4KGQ C;  1ZA3 R;  3FL7 A;  4J6G C;  4RSU D;  1JMA B;  5CIR E;  4OD2 S;  1TNR R;  1D4V A;  3IJ2 X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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