4GIQR

Crystal structure of mouse rank bound to rankl
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
164
structure length
164
Chain Sequence
CTQERHYEHLGRCCSRCEPGKYLSSKCTPTSDSVCLPCGPDEYLDTWNEEDKCLLHKVCDAGKALVAVDPGNHTAPRRCACTAGYHWNSDCECCRRNTECAPGFGAQHPLQLNKDTVCTPCLLGFFSDVFSSTDKCKPWTNCTLLGKLEAHQGTTESDVVCSSS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Protein binding/protein binding
molecule keywords Tumor necrosis factor ligand superfamily member 11
publication title RANKL Employs Distinct Binding Modes to Engage RANK and the Osteoprotegerin Decoy Receptor.
pubmed doi rcsb
source organism Mus musculus
total genus 27
structure length 164
sequence length 164
ec nomenclature
pdb deposition date 2012-08-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region
R PF18278 RANK_CRD_2 Receptor activator of the NF-KB cysteine-rich repeat domain 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 4giqR02
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 4giqR01
4GIQR 3U3SA 2AW2B 2HEYR 3QBQB 4YN0A 3U3PA 4BK5A 4OD2S 4BK4A 1JMAB 2UWIA 3TJEF 4KGGC 1TNRR 3U3TA 3FL7A 3MI8D 4MSVB 5DMJA 1ZA3R 3K51B 2HEVR 4E4DR 5BNQR 3QD6R 5IHLA 3MBWA 4N90R 4RSUD 1DU3A 4M4PA 5CIRE 1D0GR 1SG1X 1NCFA 3BUKC 1D4VA 2X10A 3WVTA 4J6GC 4M4RA 1FT4A 3MHDD 4FHQA 3U3QA 2H9GR 4I9XC 3THMF 3URFZ 1EXTA 3ME4A 3ALQR 3ME2R 3QO4A 5L36B 4MXWR 3IJ2X 3U3VA 3X3FA 4KGQC
chains in the Genus database with same CATH superfamily
2E4YA 4GIQR 3U3SA 2AW2B 2HEYR 3QBQB 4YN0A 3U3PA 4BK5A 4OD2S 4BK4A 1JMAB 2UWIA 3TJEF 4KGGC 1TNRR 2E4VA 3FL7A 3MI8D 3U3TA 4MSVB 5DMJA 1ZA3R 3K51B 2HEVR 4E4DR 5BNQR 3QD6R 2E4WA 5IHLA 3MBWA 4N90R 4RSUD 1DU3A 4M4PA 5CIRE 1D0GR 1SG1X 1NCFA 3BUKC 1D4VA 2X10A 3WVTA 2E4XA 4J6GC 4M4RA 1FT4A 3MHDD 4FHQA 3U3QA 2QR6A 2H9GR 4I9XC 3THMF 3URFZ 1EXTA 3ME4A 3ALQR 3ME2R 3QO4A 5L36B 4MXWR 3IJ2X 2E4UA 3U3VA 3X3FA 4KGQC
chains in the Genus database with same CATH topology
4GIQR 3U3SA 2AW2B 2HEYR 3QBQB 4YN0A 3U3PA 4BK5A 4OD2S 4BK4A 1JMAB 2UWIA 3TJEF 4KGGC 1TNRR 3U3TA 3FL7A 3MI8D 4MSVB 5DMJA 1ZA3R 3K51B 2HEVR 4E4DR 5BNQR 3QD6R 5IHLA 3MBWA 4N90R 4RSUD 1DU3A 4M4PA 5CIRE 1D0GR 1SG1X 1NCFA 3BUKC 1D4VA 2X10A 3WVTA 4J6GC 4M4RA 1FT4A 3MHDD 4FHQA 3U3QA 2H9GR 4I9XC 3THMF 3URFZ 1EXTA 3ME4A 3ALQR 3ME2R 3QO4A 5L36B 4MXWR 3IJ2X 3U3VA 3X3FA 4KGQC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GIQ R;  3U3S A;  2AW2 B;  2HEY R;  3QBQ B;  4YN0 A;  3U3P A;  4BK5 A;  4OD2 S;  4BK4 A;  1JMA B;  2UWI A;  3TJE F;  4KGG C;  1TNR R;  3U3T A;  3FL7 A;  3MI8 D;  4MSV B;  5DMJ A;  1ZA3 R;  3K51 B;  2HEV R;  4E4D R;  5BNQ R;  3QD6 R;  5IHL A;  3MBW A;  4N90 R;  4RSU D;  1DU3 A;  4M4P A;  5CIR E;  1D0G R;  1SG1 X;  1NCF A;  3BUK C;  1D4V A;  2X10 A;  3WVT A;  4J6G C;  4M4R A;  1FT4 A;  3MHD D;  4FHQ A;  3U3Q A;  2H9G R;  4I9X C;  3THM F;  3URF Z;  1EXT A;  3ME4 A;  3ALQ R;  3ME2 R;  3QO4 A;  5L36 B;  4MXW R;  3IJ2 X;  3U3V A;  3X3F A;  4KGQ C; 
#chains in the Genus database with same CATH topology
 2E4Y A;  4GIQ R;  3U3S A;  2AW2 B;  2HEY R;  3QBQ B;  4YN0 A;  3U3P A;  4BK5 A;  4OD2 S;  4BK4 A;  1JMA B;  2UWI A;  3TJE F;  4KGG C;  1TNR R;  2E4V A;  3FL7 A;  3MI8 D;  3U3T A;  4MSV B;  5DMJ A;  1ZA3 R;  3K51 B;  2HEV R;  4E4D R;  5BNQ R;  3QD6 R;  2E4W A;  5IHL A;  3MBW A;  4N90 R;  4RSU D;  1DU3 A;  4M4P A;  5CIR E;  1D0G R;  1SG1 X;  1NCF A;  3BUK C;  1D4V A;  2X10 A;  3WVT A;  2E4X A;  4J6G C;  4M4R A;  1FT4 A;  3MHD D;  4FHQ A;  3U3Q A;  2QR6 A;  2H9G R;  4I9X C;  3THM F;  3URF Z;  1EXT A;  3ME4 A;  3ALQ R;  3ME2 R;  3QO4 A;  5L36 B;  4MXW R;  3IJ2 X;  2E4U A;  3U3V A;  3X3F A;  4KGQ C; 
#chains in the Genus database with same CATH homology
 4GIQ R;  3U3S A;  2AW2 B;  2HEY R;  3QBQ B;  4YN0 A;  3U3P A;  4BK5 A;  4OD2 S;  4BK4 A;  1JMA B;  2UWI A;  3TJE F;  4KGG C;  1TNR R;  3U3T A;  3FL7 A;  3MI8 D;  4MSV B;  5DMJ A;  1ZA3 R;  3K51 B;  2HEV R;  4E4D R;  5BNQ R;  3QD6 R;  5IHL A;  3MBW A;  4N90 R;  4RSU D;  1DU3 A;  4M4P A;  5CIR E;  1D0G R;  1SG1 X;  1NCF A;  3BUK C;  1D4V A;  2X10 A;  3WVT A;  4J6G C;  4M4R A;  1FT4 A;  3MHD D;  4FHQ A;  3U3Q A;  2H9G R;  4I9X C;  3THM F;  3URF Z;  1EXT A;  3ME4 A;  3ALQ R;  3ME2 R;  3QO4 A;  5L36 B;  4MXW R;  3IJ2 X;  3U3V A;  3X3F A;  4KGQ C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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