4FHQA

Crystal structure of hvem
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
103
structure length
101
Chain Sequence
LPSCKEDEYPVGSECCPKCSPGYRVKEACGTGTVCEPCPPGTYIAHLNGLSKCLQCQMCDPAMGLRASRNCSRTENAVCGCSPGHFCIVQDGDHCAACRAY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Immune system
molecule keywords Tumor necrosis factor receptor superfamily member 14
publication title Increased Heterologous Protein Expression in Drosophila S2 Cells for Massive Production of Immune Ligands/Receptors and Structural Analysis of Human HVEM.
pubmed doi rcsb
source organism Homo sapiens
total genus 18
structure length 101
sequence length 103
ec nomenclature
pdb deposition date 2012-06-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 4fhqA01
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 4fhqA02
3QBQB 4MXWR 1FT4A 3ME4A 3QO4A 3TJEF 3THMF 1TNRR 2H9GR 4M4RA 5BNQR 1JMAB 4RSUD 2HEVR 1NCFA 3U3QA 4OD2S 4KGGC 3WVTA 3QD6R 4YN0A 4I9XC 1D4VA 3IJ2X 4FHQA 5CIRE 1EXTA 4GIQR 4KGQC 3URFZ 3BUKC 1SG1X 2HEYR 2AW2B 4M4PA 1D0GR 3K51B 5IHLA 4N90R 3U3SA 3U3PA 3FL7A 3ME2R 3MI8D 4BK5A 5L36B 1DU3A 4BK4A 3MBWA 1ZA3R 4J6GC 3U3TA 4MSVB 3ALQR 2X10A 3X3FA 3MHDD 4E4DR 3U3VA 5DMJA 2UWIA
chains in the Genus database with same CATH superfamily
3QBQB 4MXWR 1FT4A 3ME4A 3QO4A 3TJEF 3THMF 1TNRR 2H9GR 4M4RA 5BNQR 1JMAB 4RSUD 2HEVR 1NCFA 2E4VA 2E4UA 3U3QA 4OD2S 4KGGC 3WVTA 3QD6R 4YN0A 2E4WA 1D4VA 3IJ2X 4FHQA 4I9XC 1EXTA 2E4XA 5CIRE 4GIQR 4KGQC 3URFZ 3BUKC 1SG1X 2HEYR 2AW2B 4M4PA 1D0GR 3K51B 5IHLA 4N90R 3U3SA 3U3PA 3FL7A 3ME2R 3MI8D 4BK5A 5L36B 1DU3A 4BK4A 3MBWA 1ZA3R 4J6GC 3U3TA 4MSVB 3ALQR 2X10A 3X3FA 2QR6A 3MHDD 3U3VA 4E4DR 2E4YA 5DMJA 2UWIA
chains in the Genus database with same CATH topology
3QBQB 4MXWR 1FT4A 3ME4A 3QO4A 3TJEF 3THMF 1TNRR 2H9GR 4M4RA 5BNQR 1JMAB 4RSUD 2HEVR 1NCFA 3U3QA 4OD2S 4KGGC 3WVTA 3QD6R 4YN0A 4I9XC 1D4VA 3IJ2X 4FHQA 5CIRE 1EXTA 4GIQR 4KGQC 3URFZ 3BUKC 1SG1X 2HEYR 2AW2B 4M4PA 1D0GR 3K51B 5IHLA 4N90R 3U3SA 3U3PA 3FL7A 3ME2R 3MI8D 4BK5A 5L36B 1DU3A 4BK4A 3MBWA 1ZA3R 4J6GC 3U3TA 4MSVB 3ALQR 2X10A 3X3FA 3MHDD 4E4DR 3U3VA 5DMJA 2UWIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QBQ B;  4MXW R;  1FT4 A;  3ME4 A;  3QO4 A;  3TJE F;  3THM F;  1TNR R;  2H9G R;  4M4R A;  5BNQ R;  1JMA B;  4RSU D;  2HEV R;  1NCF A;  3U3Q A;  4OD2 S;  4KGG C;  3WVT A;  3QD6 R;  4YN0 A;  4I9X C;  1D4V A;  3IJ2 X;  4FHQ A;  5CIR E;  1EXT A;  4GIQ R;  4KGQ C;  3URF Z;  3BUK C;  1SG1 X;  2HEY R;  2AW2 B;  4M4P A;  1D0G R;  3K51 B;  5IHL A;  4N90 R;  3U3S A;  3U3P A;  3FL7 A;  3ME2 R;  3MI8 D;  4BK5 A;  5L36 B;  1DU3 A;  4BK4 A;  3MBW A;  1ZA3 R;  4J6G C;  3U3T A;  4MSV B;  3ALQ R;  2X10 A;  3X3F A;  3MHD D;  4E4D R;  3U3V A;  5DMJ A;  2UWI A; 
#chains in the Genus database with same CATH topology
 3QBQ B;  4MXW R;  1FT4 A;  3ME4 A;  3QO4 A;  3TJE F;  3THM F;  1TNR R;  2H9G R;  4M4R A;  5BNQ R;  1JMA B;  4RSU D;  2HEV R;  1NCF A;  2E4V A;  2E4U A;  3U3Q A;  4OD2 S;  4KGG C;  3WVT A;  3QD6 R;  4YN0 A;  2E4W A;  1D4V A;  3IJ2 X;  4FHQ A;  4I9X C;  1EXT A;  2E4X A;  5CIR E;  4GIQ R;  4KGQ C;  3URF Z;  3BUK C;  1SG1 X;  2HEY R;  2AW2 B;  4M4P A;  1D0G R;  3K51 B;  5IHL A;  4N90 R;  3U3S A;  3U3P A;  3FL7 A;  3ME2 R;  3MI8 D;  4BK5 A;  5L36 B;  1DU3 A;  4BK4 A;  3MBW A;  1ZA3 R;  4J6G C;  3U3T A;  4MSV B;  3ALQ R;  2X10 A;  3X3F A;  2QR6 A;  3MHD D;  3U3V A;  4E4D R;  2E4Y A;  5DMJ A;  2UWI A; 
#chains in the Genus database with same CATH homology
 3QBQ B;  4MXW R;  1FT4 A;  3ME4 A;  3QO4 A;  3TJE F;  3THM F;  1TNR R;  2H9G R;  4M4R A;  5BNQ R;  1JMA B;  4RSU D;  2HEV R;  1NCF A;  3U3Q A;  4OD2 S;  4KGG C;  3WVT A;  3QD6 R;  4YN0 A;  4I9X C;  1D4V A;  3IJ2 X;  4FHQ A;  5CIR E;  1EXT A;  4GIQ R;  4KGQ C;  3URF Z;  3BUK C;  1SG1 X;  2HEY R;  2AW2 B;  4M4P A;  1D0G R;  3K51 B;  5IHL A;  4N90 R;  3U3S A;  3U3P A;  3FL7 A;  3ME2 R;  3MI8 D;  4BK5 A;  5L36 B;  1DU3 A;  4BK4 A;  3MBW A;  1ZA3 R;  4J6G C;  3U3T A;  4MSV B;  3ALQ R;  2X10 A;  3X3F A;  3MHD D;  4E4D R;  3U3V A;  5DMJ A;  2UWI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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