1YHQU

Crystal structure of azithromycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
53
structure length
53
Chain Sequence
RECDYCGTDIEPGTGTMFVHKDGATTHFCSSKCENNADLGREARNLEWTDTAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ribosome
molecule keywords 23S Ribosomal RNA
publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
total genus 12
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2005-01-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
U PF01246 Ribosomal_L24e Ribosomal protein L24e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.170.20 Mainly Beta Roll Ribosomal Protein L24e; Chain: T; Ribosomal Protein L24e; Chain: T; 1yhqU00
3G6EU 3CCRU 2QEXU 3CCSU 3CC7U 1VQ9U 1YJWU 1M90V 3CCEU 2QA4U 3CCVU 1QVGT 1VQ5U 1YJNU 1K9MV 1VQKU 1VQNU 1W2BT 1QVFT 2OTLU 3CXCT 3CCMU 1S72U 1Q82V 1Q86V 3CC4U 3CCJU 2OTJU 1JJ2T 3CCLU 3G71U 3G4SU 1VQ4U 1KC8V 1VQPU 3CCUU 3CD6U 1M1KV 3CMEU 1KD1V 1VQOU 1VQ8U 1VQLU 3CPWT 1YHQU 3I55U 3OW2T 5AN9G 3I56U 1YJ9U 1Q7YV 1N8RV 1Q81V 1VQ7U 3CMAU 1NJIV 3CC2U 1K8AV 1VQ6U 1YITU 1K73V 1KQST 1YIJU 3CCQU 1YI2U 1VQMU
chains in the Genus database with same CATH superfamily
3CC7U 2QEXU 1YJNU 3CXCT 3CCMU 2QEZA 3CCUU 1VQ8U 1JJDA 1NJIV 1KQST 1VQKU 3CCRU 1M90V 3CCEU 3CCVU 3J7ZX 1VQ5U 3CCLU 3G71U 1VQPU 1VQOU 1VQLU 3CPWT 3ABSA 2JZ6A 1YJ9U 1Q81V 3CC2U 3CCQU 3CCSU 3ABOA 1VQ9U 2QA4U 1QVGT 1VQNU 1QVFT 4UY8X 1Q86V 1Q82V 2OTJU 3G4SU 1KC8V 3CD6U 1M1KV 1KD1V 1YHQU 3ABQA 3OW2T 5AN9G 1N8RV 1K8AV 1K73V 1VQMU 3ANYA 3G6EU 1YJWU 1K9MV 3AO0A 1W2BT 2OTLU 1S72U 3CC4U 3CCJU 3ABRA 1JJ2T 5H1SY 1VQ4U 3CMEU 5MLCY 3I55U 1VQ6U 3I56U 1Q7YV 1VQ7U 3CMAU 1YITU 1YIJU 1YI2U 5DM6U
chains in the Genus database with same CATH topology
3G6EU 3CCRU 2QEXU 3CCSU 3CC7U 1VQ9U 1YJWU 1M90V 3CCEU 2QA4U 3CCVU 1QVGT 1VQ5U 1YJNU 1K9MV 1VQKU 1VQNU 1W2BT 1QVFT 2OTLU 3CXCT 3CCMU 1S72U 1Q82V 1Q86V 3CC4U 3CCJU 2OTJU 1JJ2T 3CCLU 3G71U 3G4SU 1VQ4U 1KC8V 1VQPU 3CCUU 3CD6U 1M1KV 3CMEU 1KD1V 1VQOU 1VQ8U 1VQLU 3CPWT 1YHQU 3I55U 3OW2T 1JJDA 5AN9G 3I56U 1YJ9U 1Q7YV 1N8RV 1Q81V 1VQ7U 3CMAU 1NJIV 3CC2U 1K8AV 1VQ6U 1YITU 1K73V 1KQST 1YIJU 3CCQU 1YI2U 1VQMU
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3G6E U;  3CCR U;  2QEX U;  3CCS U;  3CC7 U;  1VQ9 U;  1YJW U;  1M90 V;  3CCE U;  2QA4 U;  3CCV U;  1QVG T;  1VQ5 U;  1YJN U;  1K9M V;  1VQK U;  1VQN U;  1W2B T;  1QVF T;  2OTL U;  3CXC T;  3CCM U;  1S72 U;  1Q82 V;  1Q86 V;  3CC4 U;  3CCJ U;  2OTJ U;  1JJ2 T;  3CCL U;  3G71 U;  3G4S U;  1VQ4 U;  1KC8 V;  1VQP U;  3CCU U;  3CD6 U;  1M1K V;  3CME U;  1KD1 V;  1VQO U;  1VQ8 U;  1VQL U;  3CPW T;  1YHQ U;  3I55 U;  3OW2 T;  5AN9 G;  3I56 U;  1YJ9 U;  1Q7Y V;  1N8R V;  1Q81 V;  1VQ7 U;  3CMA U;  1NJI V;  3CC2 U;  1K8A V;  1VQ6 U;  1YIT U;  1K73 V;  1KQS T;  1YIJ U;  3CCQ U;  1YI2 U;  1VQM U; 
#chains in the Genus database with same CATH topology
 3CC7 U;  2QEX U;  1YJN U;  3CXC T;  3CCM U;  2QEZ A;  3CCU U;  1VQ8 U;  1JJD A;  1NJI V;  1KQS T;  1VQK U;  3CCR U;  1M90 V;  3CCE U;  3CCV U;  3J7Z X;  1VQ5 U;  3CCL U;  3G71 U;  1VQP U;  1VQO U;  1VQL U;  3CPW T;  3ABS A;  2JZ6 A;  1YJ9 U;  1Q81 V;  3CC2 U;  3CCQ U;  3CCS U;  3ABO A;  1VQ9 U;  2QA4 U;  1QVG T;  1VQN U;  1QVF T;  4UY8 X;  1Q86 V;  1Q82 V;  2OTJ U;  3G4S U;  1KC8 V;  3CD6 U;  1M1K V;  1KD1 V;  1YHQ U;  3ABQ A;  3OW2 T;  5AN9 G;  1N8R V;  1K8A V;  1K73 V;  1VQM U;  3ANY A;  3G6E U;  1YJW U;  1K9M V;  3AO0 A;  1W2B T;  2OTL U;  1S72 U;  3CC4 U;  3CCJ U;  3ABR A;  1JJ2 T;  5H1S Y;  1VQ4 U;  3CME U;  5MLC Y;  3I55 U;  1VQ6 U;  3I56 U;  1Q7Y V;  1VQ7 U;  3CMA U;  1YIT U;  1YIJ U;  1YI2 U;  5DM6 U; 
#chains in the Genus database with same CATH homology
 3G6E U;  3CCR U;  2QEX U;  3CCS U;  3CC7 U;  1VQ9 U;  1YJW U;  1M90 V;  3CCE U;  2QA4 U;  3CCV U;  1QVG T;  1VQ5 U;  1YJN U;  1K9M V;  1VQK U;  1VQN U;  1W2B T;  1QVF T;  2OTL U;  3CXC T;  3CCM U;  1S72 U;  1Q82 V;  1Q86 V;  3CC4 U;  3CCJ U;  2OTJ U;  1JJ2 T;  3CCL U;  3G71 U;  3G4S U;  1VQ4 U;  1KC8 V;  1VQP U;  3CCU U;  3CD6 U;  1M1K V;  3CME U;  1KD1 V;  1VQO U;  1VQ8 U;  1VQL U;  3CPW T;  1YHQ U;  3I55 U;  3OW2 T;  1JJD A;  5AN9 G;  3I56 U;  1YJ9 U;  1Q7Y V;  1N8R V;  1Q81 V;  1VQ7 U;  3CMA U;  1NJI V;  3CC2 U;  1K8A V;  1VQ6 U;  1YIT U;  1K73 V;  1KQS T;  1YIJ U;  3CCQ U;  1YI2 U;  1VQM U; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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