3G4SU

Co-crystal structure of tiamulin bound to the large ribosomal subunit
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
53
structure length
53
Chain Sequence
RECDYCGTDIEPGTGTMFVHKDGATTHFCSSKCENNADLGREARNLEWTDTAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ribosome
molecule keywords 23S ribosomal RNA
publication title U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
pubmed doi rcsb
total genus 6
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2009-02-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.170.20 Mainly Beta Roll Ribosomal Protein L24e; Chain: T; Ribosomal Protein L24e; Chain: T; 3g4sU00
3CXCT 1Q86V 3CPWT 1K73V 1N8RV 3CC2U 3G71U 1NJIV 1S72U 3CC4U 3CCLU 3CD6U 3CCVU 1K8AV 3CC7U 3CCEU 1VQPU 3CCMU 2QA4U 1Q82V 1Q7YV 3CCRU 1YJ9U 1KD1V 1QVFT 1KC8V 3OW2T 1YHQU 3I56U 1VQKU 1VQ7U 1YIJU 1YJNU 1Q81V 1M1KV 3CMAU 1YJWU 3G6EU 1VQ5U 2OTLU 1VQ4U 1YI2U 3I55U 1YITU 2QEXU 3CCUU 2OTJU 1VQ8U 1VQ6U 1VQOU 3CCSU 1VQMU 1JJ2T 1VQLU 1M90V 3CCQU 1VQNU 5AN9G 1VQ9U 1W2BT 1K9MV 3CMEU 3CCJU 1KQST 1QVGT 3G4SU
chains in the Genus database with same CATH superfamily
3CXCT 1Q86V 3CD6U 3CCLU 3CC7U 1VQPU 1Q82V 2QA4U 1VQKU 1VQ7U 1YIJU 3ABSA 1Q81V 1M1KV 1YJWU 1VQ5U 3ABQA 2QEXU 5DM6U 3I55U 3G4SU 1K73V 3CC2U 3ABRA 1K8AV 3CCMU 1Q7YV 3OW2T 3I56U 4UY8X 3CMAU 1VQ4U 3ABOA 1YI2U 3CCUU 1VQ8U 1VQ6U 3CCSU 1JJ2T 2JZ6A 1W2BT 1KQST 1QVGT 5AN9G 1NJIV 1S72U 3CC4U 3CCVU 3CCEU 3J7ZX 1KC8V 1YHQU 1YJNU 2OTLU 1VQOU 1VQMU 3CCQU 1K9MV 2OTJU 1N8RV 3CPWT 3G71U 5H1SY 3CCRU 1YJ9U 1KD1V 1QVFT 2QEZA 3ANYA 3G6EU 5MLCY 3AO0A 1YITU 1VQLU 1M90V 1VQNU 1VQ9U 1JJDA 3CMEU 3CCJU
chains in the Genus database with same CATH topology
3CXCT 1Q86V 3CPWT 1K73V 1N8RV 3CC2U 3G71U 1NJIV 1S72U 3CC4U 3CCLU 3CD6U 3CCVU 1K8AV 3CC7U 3CCEU 1VQPU 3CCMU 2QA4U 1Q82V 1Q7YV 3CCRU 1YJ9U 1KD1V 1QVFT 1KC8V 3OW2T 1YHQU 3I56U 1VQKU 1VQ7U 1YIJU 1YJNU 1Q81V 1M1KV 3CMAU 1YJWU 3G6EU 1VQ5U 2OTLU 1VQ4U 1YI2U 3I55U 1YITU 2QEXU 3CCUU 2OTJU 1VQ8U 1VQ6U 1VQOU 3CCSU 1VQMU 1JJ2T 1VQLU 1M90V 3CCQU 1VQNU 5AN9G 1VQ9U 1JJDA 1W2BT 1K9MV 3CMEU 3CCJU 1KQST 1QVGT 3G4SU
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CXC T;  1Q86 V;  3CPW T;  1K73 V;  1N8R V;  3CC2 U;  3G71 U;  1NJI V;  1S72 U;  3CC4 U;  3CCL U;  3CD6 U;  3CCV U;  1K8A V;  3CC7 U;  3CCE U;  1VQP U;  3CCM U;  2QA4 U;  1Q82 V;  1Q7Y V;  3CCR U;  1YJ9 U;  1KD1 V;  1QVF T;  1KC8 V;  3OW2 T;  1YHQ U;  3I56 U;  1VQK U;  1VQ7 U;  1YIJ U;  1YJN U;  1Q81 V;  1M1K V;  3CMA U;  1YJW U;  3G6E U;  1VQ5 U;  2OTL U;  1VQ4 U;  1YI2 U;  3I55 U;  1YIT U;  2QEX U;  3CCU U;  2OTJ U;  1VQ8 U;  1VQ6 U;  1VQO U;  3CCS U;  1VQM U;  1JJ2 T;  1VQL U;  1M90 V;  3CCQ U;  1VQN U;  5AN9 G;  1VQ9 U;  1W2B T;  1K9M V;  3CME U;  3CCJ U;  1KQS T;  1QVG T;  3G4S U; 
#chains in the Genus database with same CATH topology
 3CXC T;  1Q86 V;  3CD6 U;  3CCL U;  3CC7 U;  1VQP U;  1Q82 V;  2QA4 U;  1VQK U;  1VQ7 U;  1YIJ U;  3ABS A;  1Q81 V;  1M1K V;  1YJW U;  1VQ5 U;  3ABQ A;  2QEX U;  5DM6 U;  3I55 U;  3G4S U;  1K73 V;  3CC2 U;  3ABR A;  1K8A V;  3CCM U;  1Q7Y V;  3OW2 T;  3I56 U;  4UY8 X;  3CMA U;  1VQ4 U;  3ABO A;  1YI2 U;  3CCU U;  1VQ8 U;  1VQ6 U;  3CCS U;  1JJ2 T;  2JZ6 A;  1W2B T;  1KQS T;  1QVG T;  5AN9 G;  1NJI V;  1S72 U;  3CC4 U;  3CCV U;  3CCE U;  3J7Z X;  1KC8 V;  1YHQ U;  1YJN U;  2OTL U;  1VQO U;  1VQM U;  3CCQ U;  1K9M V;  2OTJ U;  1N8R V;  3CPW T;  3G71 U;  5H1S Y;  3CCR U;  1YJ9 U;  1KD1 V;  1QVF T;  2QEZ A;  3ANY A;  3G6E U;  5MLC Y;  3AO0 A;  1YIT U;  1VQL U;  1M90 V;  1VQN U;  1VQ9 U;  1JJD A;  3CME U;  3CCJ U; 
#chains in the Genus database with same CATH homology
 3CXC T;  1Q86 V;  3CPW T;  1K73 V;  1N8R V;  3CC2 U;  3G71 U;  1NJI V;  1S72 U;  3CC4 U;  3CCL U;  3CD6 U;  3CCV U;  1K8A V;  3CC7 U;  3CCE U;  1VQP U;  3CCM U;  2QA4 U;  1Q82 V;  1Q7Y V;  3CCR U;  1YJ9 U;  1KD1 V;  1QVF T;  1KC8 V;  3OW2 T;  1YHQ U;  3I56 U;  1VQK U;  1VQ7 U;  1YIJ U;  1YJN U;  1Q81 V;  1M1K V;  3CMA U;  1YJW U;  3G6E U;  1VQ5 U;  2OTL U;  1VQ4 U;  1YI2 U;  3I55 U;  1YIT U;  2QEX U;  3CCU U;  2OTJ U;  1VQ8 U;  1VQ6 U;  1VQO U;  3CCS U;  1VQM U;  1JJ2 T;  1VQL U;  1M90 V;  3CCQ U;  1VQN U;  5AN9 G;  1VQ9 U;  1JJD A;  1W2B T;  1K9M V;  3CME U;  3CCJ U;  1KQS T;  1QVG T;  3G4S U; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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