3G6EU

Co-crystal structure of homoharringtonine bound to the large ribosomal subunit
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
53
structure length
53
Chain Sequence
RECDYCGTDIEPGTGTMFVHKDGATTHFCSSKCENNADLGREARNLEWTDTAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ribosome
molecule keywords 23S ribosomal RNA
publication title U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
pubmed doi rcsb
total genus 10
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2009-02-06
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.170.20 Mainly Beta Roll Ribosomal Protein L24e; Chain: T; Ribosomal Protein L24e; Chain: T; 3g6eU00
1VQ9U 2OTLU 1W2BT 1YHQU 2QA4U 1VQLU 1VQ6U 5AN9G 1YJ9U 3G71U 1K73V 1YJWU 3CPWT 1M1KV 1Q82V 3CC7U 3CCRU 1VQ7U 1VQ5U 3CC4U 1JJ2T 3CD6U 1Q86V 3CCQU 1KD1V 1VQKU 3CCEU 1KC8V 2QEXU 3CCJU 1K9MV 1KQST 1VQPU 1Q7YV 3CMEU 3CC2U 1K8AV 1NJIV 1YIJU 1YI2U 1YITU 1VQOU 3I56U 1VQ4U 1VQ8U 1VQNU 2OTJU 3CXCT 1Q81V 1QVGT 3CCLU 3CCSU 3CCUU 3I55U 1N8RV 1M90V 3CCVU 1VQMU 1S72U 3OW2T 3G4SU 1QVFT 3CCMU 1YJNU 3CMAU 3G6EU
chains in the Genus database with same CATH superfamily
1VQLU 5AN9G 1YJ9U 3CC7U 3CCQU 2QEXU 3CCJU 1K9MV 1VQPU 1K8AV 1NJIV 1YIJU 2OTJU 3J7ZX 1QVGT 3I55U 5H1SY 1QVFT 1W2BT 1VQ9U 1K73V 3CPWT 3CCRU 3CD6U 3ABSA 1KC8V 1Q7YV 3CMEU 1VQOU 1VQ4U 1VQ8U 3CCLU 3CCUU 3AO0A 1S72U 3OW2T 1VQNU 3CCMU 1VQ6U 3CMAU 3G6EU 2QA4U 1YJWU 1M1KV 1Q82V 1VQ7U 1JJ2T 1VQKU 5MLCY 1YITU 3CXCT 3CCSU 1JJDA 1N8RV 1M90V 3ANYA 3CCVU 2QEZA 2JZ6A 1VQMU 3G4SU 1YJNU 2OTLU 1YHQU 3G71U 3ABRA 3CC4U 1VQ5U 3ABOA 1Q86V 1KD1V 3ABQA 3CCEU 1KQST 4UY8X 3CC2U 1YI2U 3I56U 1Q81V 5DM6U
chains in the Genus database with same CATH topology
1VQ9U 2OTLU 1W2BT 1YHQU 2QA4U 1VQLU 1VQ6U 5AN9G 1YJ9U 3G71U 1K73V 1YJWU 3CPWT 1M1KV 1Q82V 3CC7U 3CCRU 1VQ7U 1VQ5U 3CC4U 1JJ2T 3CD6U 1Q86V 3CCQU 1KD1V 1VQKU 3CCEU 1KC8V 2QEXU 3CCJU 1K9MV 1KQST 1VQPU 1Q7YV 3CMEU 3CC2U 1K8AV 1NJIV 1YIJU 1YI2U 1YITU 1VQOU 3I56U 1VQ4U 1VQ8U 1VQNU 2OTJU 3CXCT 1Q81V 1QVGT 3CCLU 3CCSU 3CCUU 3I55U 1JJDA 1N8RV 1M90V 3CCVU 1VQMU 1S72U 3OW2T 3G4SU 1QVFT 3CCMU 1YJNU 3CMAU 3G6EU
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQ9 U;  2OTL U;  1W2B T;  1YHQ U;  2QA4 U;  1VQL U;  1VQ6 U;  5AN9 G;  1YJ9 U;  3G71 U;  1K73 V;  1YJW U;  3CPW T;  1M1K V;  1Q82 V;  3CC7 U;  3CCR U;  1VQ7 U;  1VQ5 U;  3CC4 U;  1JJ2 T;  3CD6 U;  1Q86 V;  3CCQ U;  1KD1 V;  1VQK U;  3CCE U;  1KC8 V;  2QEX U;  3CCJ U;  1K9M V;  1KQS T;  1VQP U;  1Q7Y V;  3CME U;  3CC2 U;  1K8A V;  1NJI V;  1YIJ U;  1YI2 U;  1YIT U;  1VQO U;  3I56 U;  1VQ4 U;  1VQ8 U;  1VQN U;  2OTJ U;  3CXC T;  1Q81 V;  1QVG T;  3CCL U;  3CCS U;  3CCU U;  3I55 U;  1N8R V;  1M90 V;  3CCV U;  1VQM U;  1S72 U;  3OW2 T;  3G4S U;  1QVF T;  3CCM U;  1YJN U;  3CMA U;  3G6E U; 
#chains in the Genus database with same CATH topology
 1VQL U;  5AN9 G;  1YJ9 U;  3CC7 U;  3CCQ U;  2QEX U;  3CCJ U;  1K9M V;  1VQP U;  1K8A V;  1NJI V;  1YIJ U;  2OTJ U;  3J7Z X;  1QVG T;  3I55 U;  5H1S Y;  1QVF T;  1W2B T;  1VQ9 U;  1K73 V;  3CPW T;  3CCR U;  3CD6 U;  3ABS A;  1KC8 V;  1Q7Y V;  3CME U;  1VQO U;  1VQ4 U;  1VQ8 U;  3CCL U;  3CCU U;  3AO0 A;  1S72 U;  3OW2 T;  1VQN U;  3CCM U;  1VQ6 U;  3CMA U;  3G6E U;  2QA4 U;  1YJW U;  1M1K V;  1Q82 V;  1VQ7 U;  1JJ2 T;  1VQK U;  5MLC Y;  1YIT U;  3CXC T;  3CCS U;  1JJD A;  1N8R V;  1M90 V;  3ANY A;  3CCV U;  2QEZ A;  2JZ6 A;  1VQM U;  3G4S U;  1YJN U;  2OTL U;  1YHQ U;  3G71 U;  3ABR A;  3CC4 U;  1VQ5 U;  3ABO A;  1Q86 V;  1KD1 V;  3ABQ A;  3CCE U;  1KQS T;  4UY8 X;  3CC2 U;  1YI2 U;  3I56 U;  1Q81 V;  5DM6 U; 
#chains in the Genus database with same CATH homology
 1VQ9 U;  2OTL U;  1W2B T;  1YHQ U;  2QA4 U;  1VQL U;  1VQ6 U;  5AN9 G;  1YJ9 U;  3G71 U;  1K73 V;  1YJW U;  3CPW T;  1M1K V;  1Q82 V;  3CC7 U;  3CCR U;  1VQ7 U;  1VQ5 U;  3CC4 U;  1JJ2 T;  3CD6 U;  1Q86 V;  3CCQ U;  1KD1 V;  1VQK U;  3CCE U;  1KC8 V;  2QEX U;  3CCJ U;  1K9M V;  1KQS T;  1VQP U;  1Q7Y V;  3CME U;  3CC2 U;  1K8A V;  1NJI V;  1YIJ U;  1YI2 U;  1YIT U;  1VQO U;  3I56 U;  1VQ4 U;  1VQ8 U;  1VQN U;  2OTJ U;  3CXC T;  1Q81 V;  1QVG T;  3CCL U;  3CCS U;  3CCU U;  3I55 U;  1JJD A;  1N8R V;  1M90 V;  3CCV U;  1VQM U;  1S72 U;  3OW2 T;  3G4S U;  1QVF T;  3CCM U;  1YJN U;  3CMA U;  3G6E U; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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