2BMLA

Ofloxacin-like antibiotics inhibit pneumococcal cell wall degrading virulence factors
Total Genus 15
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
125
structure length
125
Chain Sequence
YPKDKFEKINGTWYYFDSSGYMLADRWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEGAMVSNAFIQSADGTGWYYLKPDGTLADRPEFTVEPDGLITVK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Choline-binding domain
molecule keywords AUTOLYSIN
publication title Ofloxacin-Like Antibiotics Inhibit Pneumococcal Cell Wall-Degrading Virulence Factors
pubmed doi rcsb
source organism Streptococcus pneumoniae
total genus 15
structure length 125
sequence length 125
chains with identical sequence B
ec nomenclature ec 3.5.1.28: N-acetylmuramoyl-L-alanine amidase.
pdb deposition date 2005-03-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01473 CW_binding_1 Putative cell wall binding repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.270.10 Mainly Beta Ribbon left handed beta-beta-3-solenoid Cholin Binding 2bmlA00
4TTUA 2QJ6A 2J8FA 1OBAA 3HZ3A 2V04A 1GVMA 3TTQA 2X8MA 2IXUA 2X8PA 2X8OA 4AYGA 4TVDA 3HIAA 1H8GA 4TVCA 2J8GA 4NC2A 4NC0A 3KLKA 1HCXA 2G7CA 3TTOA 2VYUA 3KLLA 4X36A 2BMLA 4NBYA 4NBXA 1H09A 4NBZA 2F6EA 2IXVA 2V05A
chains in the Genus database with same CATH superfamily
4TTUA 2QJ6A 2J8FA 1OBAA 3HZ3A 2V04A 1GVMA 3TTQA 2X8MA 2IXUA 2X8PA 2X8OA 4AYGA 4TVDA 3HIAA 1H8GA 4TVCA 2J8GA 4NC2A 4NC0A 3KLKA 1HCXA 2G7CA 3TTOA 2VYUA 3KLLA 4X36A 2BMLA 4NBYA 4NBXA 1H09A 4NBZA 2F6EA 2IXVA 2V05A
chains in the Genus database with same CATH topology
4TTUA 2QJ6A 2J8FA 1OBAA 3HZ3A 2V04A 1GVMA 3TTQA 2X8MA 2IXUA 2X8PA 2X8OA 4AYGA 4TVDA 3HIAA 1H8GA 4TVCA 2J8GA 4NC2A 4NC0A 3KLKA 1HCXA 2G7CA 3TTOA 2VYUA 3KLLA 4X36A 2BMLA 4NBYA 4NBXA 1H09A 4NBZA 2F6EA 2IXVA 2V05A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4TTU A;  2QJ6 A;  2J8F A;  1OBA A;  3HZ3 A;  2V04 A;  1GVM A;  3TTQ A;  2X8M A;  2IXU A;  2X8P A;  2X8O A;  4AYG A;  4TVD A;  3HIA A;  1H8G A;  4TVC A;  2J8G A;  4NC2 A;  4NC0 A;  3KLK A;  1HCX A;  2G7C A;  3TTO A;  2VYU A;  3KLL A;  4X36 A;  2BML A;  4NBY A;  4NBX A;  1H09 A;  4NBZ A;  2F6E A;  2IXV A;  2V05 A; 
#chains in the Genus database with same CATH topology
 4TTU A;  2QJ6 A;  2J8F A;  1OBA A;  3HZ3 A;  2V04 A;  1GVM A;  3TTQ A;  2X8M A;  2IXU A;  2X8P A;  2X8O A;  4AYG A;  4TVD A;  3HIA A;  1H8G A;  4TVC A;  2J8G A;  4NC2 A;  4NC0 A;  3KLK A;  1HCX A;  2G7C A;  3TTO A;  2VYU A;  3KLL A;  4X36 A;  2BML A;  4NBY A;  4NBX A;  1H09 A;  4NBZ A;  2F6E A;  2IXV A;  2V05 A; 
#chains in the Genus database with same CATH homology
 4TTU A;  2QJ6 A;  2J8F A;  1OBA A;  3HZ3 A;  2V04 A;  1GVM A;  3TTQ A;  2X8M A;  2IXU A;  2X8P A;  2X8O A;  4AYG A;  4TVD A;  3HIA A;  1H8G A;  4TVC A;  2J8G A;  4NC2 A;  4NC0 A;  3KLK A;  1HCX A;  2G7C A;  3TTO A;  2VYU A;  3KLL A;  4X36 A;  2BML A;  4NBY A;  4NBX A;  1H09 A;  4NBZ A;  2F6E A;  2IXV A;  2V05 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...