2EGBA

Crystal structure of glu140 to asn mutant of diphthine synthase
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
265
structure length
265
Chain Sequence
MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPNGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords diphthine synthase
publication title Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
total genus 81
structure length 265
sequence length 265
chains with identical sequence B
ec nomenclature ec 2.1.1.98: Diphthine synthase.
pdb deposition date 2007-02-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 2egbA02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 2egbA01
2EEQA 2P9DA 2P6IA 2E4NA 2DV7A 2OWFA 2BB3A 2EKAA 3ND1A 2EH4A 2EMRA 2P5CA 2CBFA 1PJSA 2E8RA 1WYZA 3NEIA 2YBQA 1VA0A 2E0NA 2ED5A 2OWGA 3NUTA 2E8HA 2E0KA 2PCAA 2PB4A 3FFYA 2HR8A 2P6LA 2EH5A 1CBFA 1WDEA 2P2XA 1S4DA 2DXWA 2PCHA 1PJTA 2PB5A 3HH1A 2EK7A 2DSGA 2EHLA 2EL0A 2DV5A 2EL1A 2P6KA 2ZVCA 3KWPA 2PB6A 2PCIA 2HUXA 2PCGA 2OWUA 2NPNA 1VE2A 2ELDA 1VHVA 2HUTA 2EGLA 2EMUA 2DXVA 2OWKA 2E8SA 2DV3A 2ED3A 2EJZA 2EN5A 1V9AA 2P6DA 5HW4A 2DEKA 2EK3A 2EK2A 2OWVA 2PCMA 2DSIA 2HUQA 1WNGA 2EGSA 2EGBA 2EL2A 2DV4A 2EL3A 2HUVA 2Z6RA 3FQ6A 2DXXA 2E17A 1VCEA 2EHCA 2EK4A 3NDCA 2E4RA 2E8QA 4E16A 2ENIA 2ZVBA 2E15A 2EH2A 2QBUA 2EJKA 2E07A 2ELEA 2E08A 3I4TA 2E7RA 2P5FA 1PJQA 2PCKA 2E16A 2DSHA 2YBOA 2EJJA
chains in the Genus database with same CATH superfamily
2EEQA 2P9DA 2P6IA 3KE8A 3ZGLA 2E4NA 3KEFA 2DV7A 2OWFA 2BB3A 2EKAA 3ND1A 4N7BA 2EH4A 2EMRA 2P5CA 2CBFA 1PJSA 2E8RA 1WYZA 3NEIA 2YBQA 1VA0A 2E0NA 2ED5A 2OWGA 3NUTA 2E8HA 2E0KA 2PCAA 2PB4A 4H4DA 3ZGNA 3FFYA 3KE9A 2HR8A 2P6LA 4EB3A 2EH5A 3KEMA 3SZUA 4MUXA 3SZLA 3LMMA 1CBFA 3F7TA 1WDEA 2P2XA 1S4DA 2DXWA 2PCHA 1PJTA 2PB5A 3SZOA 3HH1A 2EK7A 2DSGA 2EHLA 2EL0A 3T0GA 2DV5A 2EL1A 2P6KA 3KELA 4H4EA 2ZVCA 3KWPA 3DNFA 2PB6A 2PCIA 2HUXA 2PCGA 3UV3A 2OWUA 2NPNA 3UTDA 1VE2A 2ELDA 1VHVA 2HUTA 2EGLA 2EMUA 2DXVA 2OWKA 3T0FA 2E8SA 2DV3A 2ED3A 2KYYA 2EJZA 2EN5A 1V9AA 2P6DA 5HW4A 2DEKA 2EK3A 3TIXB 2EK2A 2OWVA 2PCMA 2DSIA 4H4CA 2HUQA 1WNGA 2EGSA 2EGBA 2EL2A 4MUYA 2DV4A 2EL3A 2HUVA 2Z6RA 3FQ6A 2DXXA 2E17A 3UTCA 3URKA 1VCEA 2EHCA 2EK4A 3NDCA 2E4RA 2E8QA 4E16A 2ENIA 2ZVBA 2E15A 2EH2A 2QBUA 2EJKA 2E07A 2ELEA 2E08A 3UV7A 3I4TA 2E7RA 2P5FA 1PJQA 2PCKA 3UWMA 2E16A 4MV5A 3UV6A 2DSHA 2YBOA 2EJJA 4MV0A
chains in the Genus database with same CATH topology
2EEQA 2P9DA 2P6IA 3KE8A 3ZGLA 2E4NA 3KEFA 2DV7A 2OWFA 2BB3A 2EKAA 3ND1A 4N7BA 2EH4A 2EMRA 2P5CA 2CBFA 1PJSA 2E8RA 1WYZA 3NEIA 2YBQA 1VA0A 2E0NA 2ED5A 2OWGA 3NUTA 2E8HA 2E0KA 2PCAA 2PB4A 4H4DA 3ZGNA 3FFYA 3KE9A 2HR8A 2P6LA 4EB3A 2EH5A 3KEMA 3SZUA 4MUXA 3SZLA 3LMMA 1CBFA 3F7TA 1WDEA 2P2XA 1S4DA 2DXWA 2PCHA 1PJTA 2PB5A 3SZOA 3HH1A 2EK7A 2DSGA 2EHLA 2EL0A 3T0GA 2DV5A 2EL1A 2P6KA 3KELA 4H4EA 2ZVCA 3KWPA 3DNFA 2PB6A 2PCIA 2HUXA 2PCGA 3UV3A 2OWUA 2NPNA 3UTDA 1VE2A 2ELDA 1VHVA 2HUTA 2EGLA 2EMUA 2DXVA 2OWKA 3T0FA 2E8SA 2DV3A 2ED3A 2KYYA 2EJZA 2EN5A 1V9AA 2P6DA 5HW4A 2DEKA 2EK3A 3TIXB 2EK2A 2OWVA 2PCMA 2DSIA 4H4CA 2HUQA 1WNGA 2EGSA 2EGBA 2EL2A 4MUYA 2DV4A 2EL3A 2HUVA 2Z6RA 3FQ6A 2DXXA 2E17A 3UTCA 3URKA 1VCEA 2EHCA 2EK4A 3NDCA 2E4RA 2E8QA 4E16A 2ENIA 2ZVBA 2E15A 2EH2A 2QBUA 2EJKA 2E07A 2ELEA 2E08A 3UV7A 3I4TA 2E7RA 2P5FA 1PJQA 2PCKA 3UWMA 2E16A 4MV5A 3UV6A 2DSHA 2YBOA 2EJJA 4MV0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EEQ A;  2P9D A;  2P6I A;  2E4N A;  2DV7 A;  2OWF A;  2BB3 A;  2EKA A;  3ND1 A;  2EH4 A;  2EMR A;  2P5C A;  2CBF A;  1PJS A;  2E8R A;  1WYZ A;  3NEI A;  2YBQ A;  1VA0 A;  2E0N A;  2ED5 A;  2OWG A;  3NUT A;  2E8H A;  2E0K A;  2PCA A;  2PB4 A;  3FFY A;  2HR8 A;  2P6L A;  2EH5 A;  1CBF A;  1WDE A;  2P2X A;  1S4D A;  2DXW A;  2PCH A;  1PJT A;  2PB5 A;  3HH1 A;  2EK7 A;  2DSG A;  2EHL A;  2EL0 A;  2DV5 A;  2EL1 A;  2P6K A;  2ZVC A;  3KWP A;  2PB6 A;  2PCI A;  2HUX A;  2PCG A;  2OWU A;  2NPN A;  1VE2 A;  2ELD A;  1VHV A;  2HUT A;  2EGL A;  2EMU A;  2DXV A;  2OWK A;  2E8S A;  2DV3 A;  2ED3 A;  2EJZ A;  2EN5 A;  1V9A A;  2P6D A;  5HW4 A;  2DEK A;  2EK3 A;  2EK2 A;  2OWV A;  2PCM A;  2DSI A;  2HUQ A;  1WNG A;  2EGS A;  2EGB A;  2EL2 A;  2DV4 A;  2EL3 A;  2HUV A;  2Z6R A;  3FQ6 A;  2DXX A;  2E17 A;  1VCE A;  2EHC A;  2EK4 A;  3NDC A;  2E4R A;  2E8Q A;  4E16 A;  2ENI A;  2ZVB A;  2E15 A;  2EH2 A;  2QBU A;  2EJK A;  2E07 A;  2ELE A;  2E08 A;  3I4T A;  2E7R A;  2P5F A;  1PJQ A;  2PCK A;  2E16 A;  2DSH A;  2YBO A;  2EJJ A; 
#chains in the Genus database with same CATH topology
 2EEQ A;  2P9D A;  2P6I A;  3KE8 A;  3ZGL A;  2E4N A;  3KEF A;  2DV7 A;  2OWF A;  2BB3 A;  2EKA A;  3ND1 A;  4N7B A;  2EH4 A;  2EMR A;  2P5C A;  2CBF A;  1PJS A;  2E8R A;  1WYZ A;  3NEI A;  2YBQ A;  1VA0 A;  2E0N A;  2ED5 A;  2OWG A;  3NUT A;  2E8H A;  2E0K A;  2PCA A;  2PB4 A;  4H4D A;  3ZGN A;  3FFY A;  3KE9 A;  2HR8 A;  2P6L A;  4EB3 A;  2EH5 A;  3KEM A;  3SZU A;  4MUX A;  3SZL A;  3LMM A;  1CBF A;  3F7T A;  1WDE A;  2P2X A;  1S4D A;  2DXW A;  2PCH A;  1PJT A;  2PB5 A;  3SZO A;  3HH1 A;  2EK7 A;  2DSG A;  2EHL A;  2EL0 A;  3T0G A;  2DV5 A;  2EL1 A;  2P6K A;  3KEL A;  4H4E A;  2ZVC A;  3KWP A;  3DNF A;  2PB6 A;  2PCI A;  2HUX A;  2PCG A;  3UV3 A;  2OWU A;  2NPN A;  3UTD A;  1VE2 A;  2ELD A;  1VHV A;  2HUT A;  2EGL A;  2EMU A;  2DXV A;  2OWK A;  3T0F A;  2E8S A;  2DV3 A;  2ED3 A;  2KYY A;  2EJZ A;  2EN5 A;  1V9A A;  2P6D A;  5HW4 A;  2DEK A;  2EK3 A;  3TIX B;  2EK2 A;  2OWV A;  2PCM A;  2DSI A;  4H4C A;  2HUQ A;  1WNG A;  2EGS A;  2EGB A;  2EL2 A;  4MUY A;  2DV4 A;  2EL3 A;  2HUV A;  2Z6R A;  3FQ6 A;  2DXX A;  2E17 A;  3UTC A;  3URK A;  1VCE A;  2EHC A;  2EK4 A;  3NDC A;  2E4R A;  2E8Q A;  4E16 A;  2ENI A;  2ZVB A;  2E15 A;  2EH2 A;  2QBU A;  2EJK A;  2E07 A;  2ELE A;  2E08 A;  3UV7 A;  3I4T A;  2E7R A;  2P5F A;  1PJQ A;  2PCK A;  3UWM A;  2E16 A;  4MV5 A;  3UV6 A;  2DSH A;  2YBO A;  2EJJ A;  4MV0 A; 
#chains in the Genus database with same CATH homology
 2EEQ A;  2P9D A;  2P6I A;  3KE8 A;  3ZGL A;  2E4N A;  3KEF A;  2DV7 A;  2OWF A;  2BB3 A;  2EKA A;  3ND1 A;  4N7B A;  2EH4 A;  2EMR A;  2P5C A;  2CBF A;  1PJS A;  2E8R A;  1WYZ A;  3NEI A;  2YBQ A;  1VA0 A;  2E0N A;  2ED5 A;  2OWG A;  3NUT A;  2E8H A;  2E0K A;  2PCA A;  2PB4 A;  4H4D A;  3ZGN A;  3FFY A;  3KE9 A;  2HR8 A;  2P6L A;  4EB3 A;  2EH5 A;  3KEM A;  3SZU A;  4MUX A;  3SZL A;  3LMM A;  1CBF A;  3F7T A;  1WDE A;  2P2X A;  1S4D A;  2DXW A;  2PCH A;  1PJT A;  2PB5 A;  3SZO A;  3HH1 A;  2EK7 A;  2DSG A;  2EHL A;  2EL0 A;  3T0G A;  2DV5 A;  2EL1 A;  2P6K A;  3KEL A;  4H4E A;  2ZVC A;  3KWP A;  3DNF A;  2PB6 A;  2PCI A;  2HUX A;  2PCG A;  3UV3 A;  2OWU A;  2NPN A;  3UTD A;  1VE2 A;  2ELD A;  1VHV A;  2HUT A;  2EGL A;  2EMU A;  2DXV A;  2OWK A;  3T0F A;  2E8S A;  2DV3 A;  2ED3 A;  2KYY A;  2EJZ A;  2EN5 A;  1V9A A;  2P6D A;  5HW4 A;  2DEK A;  2EK3 A;  3TIX B;  2EK2 A;  2OWV A;  2PCM A;  2DSI A;  4H4C A;  2HUQ A;  1WNG A;  2EGS A;  2EGB A;  2EL2 A;  4MUY A;  2DV4 A;  2EL3 A;  2HUV A;  2Z6R A;  3FQ6 A;  2DXX A;  2E17 A;  3UTC A;  3URK A;  1VCE A;  2EHC A;  2EK4 A;  3NDC A;  2E4R A;  2E8Q A;  4E16 A;  2ENI A;  2ZVB A;  2E15 A;  2EH2 A;  2QBU A;  2EJK A;  2E07 A;  2ELE A;  2E08 A;  3UV7 A;  3I4T A;  2E7R A;  2P5F A;  1PJQ A;  2PCK A;  3UWM A;  2E16 A;  4MV5 A;  3UV6 A;  2DSH A;  2YBO A;  2EJJ A;  4MV0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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