3HMRA

Crystal structure of the n-terminal fragment (31-127) of the mouse hepatocyte growth factor/scatter factor
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
90
structure length
90
Chain Sequence
NTLHEFKKSAKTTLTKEDPLLKIKTKKVNSADECANRCIRNRGFTFTCKAFVFDKSRKRCYWYPFNSMSSGVKKGFGHEFDLYENKDYIR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hormone
molecule keywords Hepatocyte growth factor
publication title Structural basis for agonism and antagonism of hepatocyte growth factor.
pubmed doi rcsb
source organism Mus musculus
total genus 23
structure length 90
sequence length 90
ec nomenclature
pdb deposition date 2009-05-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00024 PAN_1 PAN domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 3hmrA00
1W8KA 2K13X 5COEA 3ZLEA 2Q8AA 2Y8RA 1BHTA 2J8LA 1GMNA 4Z0FA 2Z8VA 1GP9A 1GMOA 2F83A 3HN4A 2Q8BA 5CSQA 5EODA 3HMRA 4APLA 3HMTA 1YXEA 2X2ZA 2YIOA 3MKPA 4IUAA 4R1CA 3SP8A 3SRJA 5I25A 4Z0DA 5CP9A 2Z8WA 2J8JA 5CT2A 4R19A 2HGFA 5CS3A 4APMA 1NK1A 4A5TS 5CT3A 5EOKA 1HKYA 2QJ2A 1I8NA 4Z0EA 2LL4M 4UV6A 4R1AA 2LL3A 1Z40A 5CS1A 2QJ4A 4UAOA 4R1BA 2YILA 4DURA 5CS5A 3HMSA 3SRIA 5CT1A 1W81A 5CS9A 2YIPA 3ZWZA 4Z09A
chains in the Genus database with same CATH superfamily
1W8KA 2K13X 5COEA 3ZLEA 2Q8AA 2Y8RA 1BHTA 2J8LA 1GMNA 4Z0FA 2Z8VA 1GP9A 1GMOA 2F83A 3HN4A 2Q8BA 5CSQA 5EODA 3HMRA 4APLA 3HMTA 1YXEA 2X2ZA 2YIOA 3MKPA 4YIVA 4IUAA 4R1CA 3SP8A 3SRJA 5I25A 4Z0DA 5CP9A 2Z8WA 2J8JA 5CT2A 4R19A 2HGFA 5CS3A 4APMA 1NK1A 4A5TS 5CT3A 5EOKA 1HKYA 2QJ2A 1I8NA 4Z0EA 2LL4M 4UV6A 4R1AA 2LL3A 1Z40A 5CS1A 2QJ4A 4UAOA 4R1BA 2YILA 4DURA 5CS5A 3HMSA 3SRIA 2KL5A 4YIZA 5CT1A 1W81A 5CS9A 2YIPA 3ZWZA 4Z09A
chains in the Genus database with same CATH topology
1W8KA 2K13X 5COEA 3ZLEA 2Q8AA 2Y8RA 1BHTA 2J8LA 1GMNA 4Z0FA 2Z8VA 1GP9A 1GMOA 2F83A 3HN4A 2Q8BA 5CSQA 5EODA 3HMRA 4APLA 3HMTA 1YXEA 2X2ZA 2YIOA 3MKPA 4YIVA 4IUAA 4R1CA 3SP8A 3SRJA 5I25A 4Z0DA 5CP9A 2Z8WA 2J8JA 5CT2A 4R19A 2HGFA 5CS3A 4APMA 1NK1A 4A5TS 5CT3A 5EOKA 1HKYA 2QJ2A 1I8NA 4Z0EA 2LL4M 4UV6A 4R1AA 2LL3A 1Z40A 5CS1A 2QJ4A 4UAOA 4R1BA 2YILA 4DURA 5CS5A 3HMSA 3SRIA 2KL5A 4YIZA 5CT1A 1W81A 5CS9A 2YIPA 3ZWZA 4Z09A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1W8K A;  2K13 X;  5COE A;  3ZLE A;  2Q8A A;  2Y8R A;  1BHT A;  2J8L A;  1GMN A;  4Z0F A;  2Z8V A;  1GP9 A;  1GMO A;  2F83 A;  3HN4 A;  2Q8B A;  5CSQ A;  5EOD A;  3HMR A;  4APL A;  3HMT A;  1YXE A;  2X2Z A;  2YIO A;  3MKP A;  4IUA A;  4R1C A;  3SP8 A;  3SRJ A;  5I25 A;  4Z0D A;  5CP9 A;  2Z8W A;  2J8J A;  5CT2 A;  4R19 A;  2HGF A;  5CS3 A;  4APM A;  1NK1 A;  4A5T S;  5CT3 A;  5EOK A;  1HKY A;  2QJ2 A;  1I8N A;  4Z0E A;  2LL4 M;  4UV6 A;  4R1A A;  2LL3 A;  1Z40 A;  5CS1 A;  2QJ4 A;  4UAO A;  4R1B A;  2YIL A;  4DUR A;  5CS5 A;  3HMS A;  3SRI A;  5CT1 A;  1W81 A;  5CS9 A;  2YIP A;  3ZWZ A;  4Z09 A; 
#chains in the Genus database with same CATH topology
 1W8K A;  2K13 X;  5COE A;  3ZLE A;  2Q8A A;  2Y8R A;  1BHT A;  2J8L A;  1GMN A;  4Z0F A;  2Z8V A;  1GP9 A;  1GMO A;  2F83 A;  3HN4 A;  2Q8B A;  5CSQ A;  5EOD A;  3HMR A;  4APL A;  3HMT A;  1YXE A;  2X2Z A;  2YIO A;  3MKP A;  4YIV A;  4IUA A;  4R1C A;  3SP8 A;  3SRJ A;  5I25 A;  4Z0D A;  5CP9 A;  2Z8W A;  2J8J A;  5CT2 A;  4R19 A;  2HGF A;  5CS3 A;  4APM A;  1NK1 A;  4A5T S;  5CT3 A;  5EOK A;  1HKY A;  2QJ2 A;  1I8N A;  4Z0E A;  2LL4 M;  4UV6 A;  4R1A A;  2LL3 A;  1Z40 A;  5CS1 A;  2QJ4 A;  4UAO A;  4R1B A;  2YIL A;  4DUR A;  5CS5 A;  3HMS A;  3SRI A;  2KL5 A;  4YIZ A;  5CT1 A;  1W81 A;  5CS9 A;  2YIP A;  3ZWZ A;  4Z09 A; 
#chains in the Genus database with same CATH homology
 1W8K A;  2K13 X;  5COE A;  3ZLE A;  2Q8A A;  2Y8R A;  1BHT A;  2J8L A;  1GMN A;  4Z0F A;  2Z8V A;  1GP9 A;  1GMO A;  2F83 A;  3HN4 A;  2Q8B A;  5CSQ A;  5EOD A;  3HMR A;  4APL A;  3HMT A;  1YXE A;  2X2Z A;  2YIO A;  3MKP A;  4YIV A;  4IUA A;  4R1C A;  3SP8 A;  3SRJ A;  5I25 A;  4Z0D A;  5CP9 A;  2Z8W A;  2J8J A;  5CT2 A;  4R19 A;  2HGF A;  5CS3 A;  4APM A;  1NK1 A;  4A5T S;  5CT3 A;  5EOK A;  1HKY A;  2QJ2 A;  1I8N A;  4Z0E A;  2LL4 M;  4UV6 A;  4R1A A;  2LL3 A;  1Z40 A;  5CS1 A;  2QJ4 A;  4UAO A;  4R1B A;  2YIL A;  4DUR A;  5CS5 A;  3HMS A;  3SRI A;  2KL5 A;  4YIZ A;  5CT1 A;  1W81 A;  5CS9 A;  2YIP A;  3ZWZ A;  4Z09 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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