4Z0FA

Crystal structure of fvo strain plasmodium falciparum ama1 in complex with the ron2hp [phe2038(6cw)] peptide
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
332
structure length
278
Chain Sequence
GNPWTEYMAKYDIEEVHGSGIRVDLGEDAEVAGTQYRLPSGKCPVFGKGIIIENSNTTFLKPVATLKDGGFAFPPTNPLISPMTLNGMRDFYKNNEYVKNLDELTLCSRHAGNMNPDNKNSNYKYPAVYDYNDKKCHILYIAAQENNFCFRPAKDKLFENYTYLSKNVVDNWEEVCPRKNLENAKFGLWVDGNCEDIPHVNEFSANDLFECNKLVFELSASDQPKQYDRYKSHGKGYNWGNYNRETQKCEIFNVKPTCLINNSSYIATTALSHPIEVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cell invasion
molecule keywords Apical membrane antigen 1
publication title Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
pubmed doi rcsb
source organism Plasmodium falciparum vietnam oak-knoll (fvo)
total genus 75
structure length 278
sequence length 332
ec nomenclature
pdb deposition date 2015-03-26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 4z0fA01
5COEA 4Z0DA 2J8JA 5CS9A 2Q8AA 2YILA 5CS3A 3ZWZA 5CP9A 2HGFA 1GP9A 4R1CA 4Z0FA 3HMTA 2Q8BA 1GMOA 3SRIA 1W8KA 1NK1A 4R1BA 4UV6A 5CT2A 4APLA 4DURA 5CT1A 3SRJA 2Z8WA 3ZLEA 2QJ4A 3HN4A 1GMNA 4R19A 1HKYA 2Y8RA 1I8NA 1Z40A 2J8LA 4UAOA 5EODA 4APMA 1BHTA 3MKPA 4A5TS 4IUAA 4Z09A 3SP8A 2YIPA 3HMSA 2LL4M 5CS5A 2YIOA 2K13X 5CS1A 5I25A 5CT3A 1YXEA 5CSQA 1W81A 4Z0EA 3HMRA 5EOKA 2LL3A 2Z8VA 2X2ZA 4R1AA 2F83A 2QJ2A
chains in the Genus database with same CATH superfamily
5COEA 4YIVA 4Z0DA 2J8JA 5CS9A 2Q8AA 2YILA 5CS3A 3ZWZA 4YIZA 5CP9A 2HGFA 1GP9A 4R1CA 4Z0FA 3HMTA 2Q8BA 1GMOA 3SRIA 2KL5A 1W8KA 1NK1A 4R1BA 4UV6A 5CT2A 4APLA 4DURA 5CT1A 3SRJA 2Z8WA 3ZLEA 2QJ4A 3HN4A 1GMNA 4R19A 1HKYA 2Y8RA 1I8NA 1Z40A 2J8LA 4UAOA 5EODA 4APMA 1BHTA 3MKPA 4A5TS 4IUAA 4Z09A 3SP8A 2YIPA 3HMSA 2LL4M 5CS5A 2YIOA 2K13X 5CS1A 5I25A 5CT3A 1YXEA 5CSQA 1W81A 4Z0EA 3HMRA 5EOKA 2LL3A 2Z8VA 2X2ZA 4R1AA 2F83A 2QJ2A
chains in the Genus database with same CATH topology
5COEA 4YIVA 4Z0DA 2J8JA 5CS9A 2Q8AA 2YILA 5CS3A 3ZWZA 4YIZA 5CP9A 2HGFA 1GP9A 4R1CA 4Z0FA 3HMTA 2Q8BA 1GMOA 3SRIA 2KL5A 1W8KA 1NK1A 4R1BA 4UV6A 5CT2A 4APLA 4DURA 5CT1A 3SRJA 2Z8WA 3ZLEA 2QJ4A 3HN4A 1GMNA 4R19A 1HKYA 2Y8RA 1I8NA 1Z40A 2J8LA 4UAOA 5EODA 4APMA 1BHTA 3MKPA 4A5TS 4IUAA 4Z09A 3SP8A 2YIPA 3HMSA 2LL4M 5CS5A 2YIOA 2K13X 5CS1A 5I25A 5CT3A 1YXEA 5CSQA 1W81A 4Z0EA 3HMRA 5EOKA 2LL3A 2Z8VA 2X2ZA 4R1AA 2F83A 2QJ2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5COE A;  4Z0D A;  2J8J A;  5CS9 A;  2Q8A A;  2YIL A;  5CS3 A;  3ZWZ A;  5CP9 A;  2HGF A;  1GP9 A;  4R1C A;  4Z0F A;  3HMT A;  2Q8B A;  1GMO A;  3SRI A;  1W8K A;  1NK1 A;  4R1B A;  4UV6 A;  5CT2 A;  4APL A;  4DUR A;  5CT1 A;  3SRJ A;  2Z8W A;  3ZLE A;  2QJ4 A;  3HN4 A;  1GMN A;  4R19 A;  1HKY A;  2Y8R A;  1I8N A;  1Z40 A;  2J8L A;  4UAO A;  5EOD A;  4APM A;  1BHT A;  3MKP A;  4A5T S;  4IUA A;  4Z09 A;  3SP8 A;  2YIP A;  3HMS A;  2LL4 M;  5CS5 A;  2YIO A;  2K13 X;  5CS1 A;  5I25 A;  5CT3 A;  1YXE A;  5CSQ A;  1W81 A;  4Z0E A;  3HMR A;  5EOK A;  2LL3 A;  2Z8V A;  2X2Z A;  4R1A A;  2F83 A;  2QJ2 A; 
#chains in the Genus database with same CATH topology
 5COE A;  4YIV A;  4Z0D A;  2J8J A;  5CS9 A;  2Q8A A;  2YIL A;  5CS3 A;  3ZWZ A;  4YIZ A;  5CP9 A;  2HGF A;  1GP9 A;  4R1C A;  4Z0F A;  3HMT A;  2Q8B A;  1GMO A;  3SRI A;  2KL5 A;  1W8K A;  1NK1 A;  4R1B A;  4UV6 A;  5CT2 A;  4APL A;  4DUR A;  5CT1 A;  3SRJ A;  2Z8W A;  3ZLE A;  2QJ4 A;  3HN4 A;  1GMN A;  4R19 A;  1HKY A;  2Y8R A;  1I8N A;  1Z40 A;  2J8L A;  4UAO A;  5EOD A;  4APM A;  1BHT A;  3MKP A;  4A5T S;  4IUA A;  4Z09 A;  3SP8 A;  2YIP A;  3HMS A;  2LL4 M;  5CS5 A;  2YIO A;  2K13 X;  5CS1 A;  5I25 A;  5CT3 A;  1YXE A;  5CSQ A;  1W81 A;  4Z0E A;  3HMR A;  5EOK A;  2LL3 A;  2Z8V A;  2X2Z A;  4R1A A;  2F83 A;  2QJ2 A; 
#chains in the Genus database with same CATH homology
 5COE A;  4YIV A;  4Z0D A;  2J8J A;  5CS9 A;  2Q8A A;  2YIL A;  5CS3 A;  3ZWZ A;  4YIZ A;  5CP9 A;  2HGF A;  1GP9 A;  4R1C A;  4Z0F A;  3HMT A;  2Q8B A;  1GMO A;  3SRI A;  2KL5 A;  1W8K A;  1NK1 A;  4R1B A;  4UV6 A;  5CT2 A;  4APL A;  4DUR A;  5CT1 A;  3SRJ A;  2Z8W A;  3ZLE A;  2QJ4 A;  3HN4 A;  1GMN A;  4R19 A;  1HKY A;  2Y8R A;  1I8N A;  1Z40 A;  2J8L A;  4UAO A;  5EOD A;  4APM A;  1BHT A;  3MKP A;  4A5T S;  4IUA A;  4Z09 A;  3SP8 A;  2YIP A;  3HMS A;  2LL4 M;  5CS5 A;  2YIO A;  2K13 X;  5CS1 A;  5I25 A;  5CT3 A;  1YXE A;  5CSQ A;  1W81 A;  4Z0E A;  3HMR A;  5EOK A;  2LL3 A;  2Z8V A;  2X2Z A;  4R1A A;  2F83 A;  2QJ2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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