3HMTA

Crystal structure of the n-terminal fragment (28-126) of the human hepatocyte growth factor/scatter factor, trigonal crystal form
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
91
structure length
91
Chain Sequence
RNTIHEFKKSAKTTLIKIDPALKIKTKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYENKDYIR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hormone
molecule keywords Hepatocyte growth factor
publication title Structural basis for agonism and antagonism of hepatocyte growth factor.
pubmed doi rcsb
source organism Homo sapiens
total genus 25
structure length 91
sequence length 91
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-05-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00024 PAN_1 PAN domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 3hmtA00
5CT2A 4UV6A 4Z0DA 5EODA 2F83A 3ZLEA 1GP9A 2QJ2A 1BHTA 1HKYA 4R1AA 1W81A 2HGFA 5CSQA 5CS1A 3HMRA 4APLA 4Z0EA 1YXEA 1GMNA 3MKPA 3SRJA 2Q8BA 5CT3A 5I25A 2YIOA 1W8KA 4R19A 4DURA 2Z8WA 2Q8AA 2J8LA 1Z40A 3HN4A 3HMTA 3SP8A 3SRIA 2K13X 5CP9A 1GMOA 1I8NA 4Z09A 4R1CA 4Z0FA 4A5TS 2Z8VA 2QJ4A 2X2ZA 5EOKA 5CS9A 4APMA 4R1BA 5CS5A 5COEA 3ZWZA 4IUAA 2LL4M 5CS3A 2YIPA 2LL3A 3HMSA 4UAOA 1NK1A 2J8JA 2Y8RA 2YILA 5CT1A
chains in the Genus database with same CATH superfamily
5CT2A 4UV6A 4YIVA 4Z0DA 5EODA 2F83A 3ZLEA 1GP9A 2QJ2A 1BHTA 1HKYA 4R1AA 1W81A 2HGFA 5CSQA 5CS1A 3HMRA 4APLA 4Z0EA 1YXEA 1GMNA 3MKPA 3SRJA 2Q8BA 5CT3A 5I25A 2YIOA 4YIZA 1W8KA 4R19A 4DURA 2Z8WA 2Q8AA 2J8LA 1Z40A 3HN4A 3HMTA 3SP8A 3SRIA 2K13X 5CP9A 1GMOA 1I8NA 2KL5A 4Z09A 4R1CA 4Z0FA 4A5TS 2Z8VA 2QJ4A 2X2ZA 5EOKA 5CS9A 4APMA 4R1BA 5CS5A 5COEA 3ZWZA 4IUAA 2LL4M 5CS3A 2YIPA 2LL3A 3HMSA 4UAOA 1NK1A 2J8JA 2Y8RA 2YILA 5CT1A
chains in the Genus database with same CATH topology
5CT2A 4UV6A 4YIVA 4Z0DA 5EODA 2F83A 3ZLEA 1GP9A 2QJ2A 1BHTA 1HKYA 4R1AA 1W81A 2HGFA 5CSQA 5CS1A 3HMRA 4APLA 4Z0EA 1YXEA 1GMNA 3MKPA 3SRJA 2Q8BA 5CT3A 5I25A 2YIOA 4YIZA 1W8KA 4R19A 4DURA 2Z8WA 2Q8AA 2J8LA 1Z40A 3HN4A 3HMTA 3SP8A 3SRIA 2K13X 5CP9A 1GMOA 1I8NA 2KL5A 4Z09A 4R1CA 4Z0FA 4A5TS 2Z8VA 2QJ4A 2X2ZA 5EOKA 5CS9A 4APMA 4R1BA 5CS5A 5COEA 3ZWZA 4IUAA 2LL4M 5CS3A 2YIPA 2LL3A 3HMSA 4UAOA 1NK1A 2J8JA 2Y8RA 2YILA 5CT1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5CT2 A;  4UV6 A;  4Z0D A;  5EOD A;  2F83 A;  3ZLE A;  1GP9 A;  2QJ2 A;  1BHT A;  1HKY A;  4R1A A;  1W81 A;  2HGF A;  5CSQ A;  5CS1 A;  3HMR A;  4APL A;  4Z0E A;  1YXE A;  1GMN A;  3MKP A;  3SRJ A;  2Q8B A;  5CT3 A;  5I25 A;  2YIO A;  1W8K A;  4R19 A;  4DUR A;  2Z8W A;  2Q8A A;  2J8L A;  1Z40 A;  3HN4 A;  3HMT A;  3SP8 A;  3SRI A;  2K13 X;  5CP9 A;  1GMO A;  1I8N A;  4Z09 A;  4R1C A;  4Z0F A;  4A5T S;  2Z8V A;  2QJ4 A;  2X2Z A;  5EOK A;  5CS9 A;  4APM A;  4R1B A;  5CS5 A;  5COE A;  3ZWZ A;  4IUA A;  2LL4 M;  5CS3 A;  2YIP A;  2LL3 A;  3HMS A;  4UAO A;  1NK1 A;  2J8J A;  2Y8R A;  2YIL A;  5CT1 A; 
#chains in the Genus database with same CATH topology
 5CT2 A;  4UV6 A;  4YIV A;  4Z0D A;  5EOD A;  2F83 A;  3ZLE A;  1GP9 A;  2QJ2 A;  1BHT A;  1HKY A;  4R1A A;  1W81 A;  2HGF A;  5CSQ A;  5CS1 A;  3HMR A;  4APL A;  4Z0E A;  1YXE A;  1GMN A;  3MKP A;  3SRJ A;  2Q8B A;  5CT3 A;  5I25 A;  2YIO A;  4YIZ A;  1W8K A;  4R19 A;  4DUR A;  2Z8W A;  2Q8A A;  2J8L A;  1Z40 A;  3HN4 A;  3HMT A;  3SP8 A;  3SRI A;  2K13 X;  5CP9 A;  1GMO A;  1I8N A;  2KL5 A;  4Z09 A;  4R1C A;  4Z0F A;  4A5T S;  2Z8V A;  2QJ4 A;  2X2Z A;  5EOK A;  5CS9 A;  4APM A;  4R1B A;  5CS5 A;  5COE A;  3ZWZ A;  4IUA A;  2LL4 M;  5CS3 A;  2YIP A;  2LL3 A;  3HMS A;  4UAO A;  1NK1 A;  2J8J A;  2Y8R A;  2YIL A;  5CT1 A; 
#chains in the Genus database with same CATH homology
 5CT2 A;  4UV6 A;  4YIV A;  4Z0D A;  5EOD A;  2F83 A;  3ZLE A;  1GP9 A;  2QJ2 A;  1BHT A;  1HKY A;  4R1A A;  1W81 A;  2HGF A;  5CSQ A;  5CS1 A;  3HMR A;  4APL A;  4Z0E A;  1YXE A;  1GMN A;  3MKP A;  3SRJ A;  2Q8B A;  5CT3 A;  5I25 A;  2YIO A;  4YIZ A;  1W8K A;  4R19 A;  4DUR A;  2Z8W A;  2Q8A A;  2J8L A;  1Z40 A;  3HN4 A;  3HMT A;  3SP8 A;  3SRI A;  2K13 X;  5CP9 A;  1GMO A;  1I8N A;  2KL5 A;  4Z09 A;  4R1C A;  4Z0F A;  4A5T S;  2Z8V A;  2QJ4 A;  2X2Z A;  5EOK A;  5CS9 A;  4APM A;  4R1B A;  5CS5 A;  5COE A;  3ZWZ A;  4IUA A;  2LL4 M;  5CS3 A;  2YIP A;  2LL3 A;  3HMS A;  4UAO A;  1NK1 A;  2J8J A;  2Y8R A;  2YIL A;  5CT1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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