4Z0DA

Crystal structure of fvo strain plasmodium falciparum ama1 in complex with the ron2hp [phe2038trp] peptide
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
331
structure length
273
Chain Sequence
NPWTEYMAKYDIEEVHGSGIRVDLGEDAEVAGTQYRLPSGKCPVFGKGIIIETTFLKPVATLKDGGFAFPPTNPLISPMTLNGMRDFYKNNEYVKNLDELTLCSRHAGNMNPDNDKNSNYKYPAVYDYNDKKCHILYIAAQENNFCFRPAKDKLFENYTYLSKNVVDNWEEVCPRKNLENAKFGLWVDGNCEDIPHVNEFSANDLFECNKLVFELSASDQPKDRYKSHGKGYNWGNYNRETQKCEIFNVKPTCLINNSSYIATTALSHPIEVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cell invasion
molecule keywords Apical membrane antigen 1
publication title Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
pubmed doi rcsb
source organism Plasmodium falciparum vietnam oak-knoll (fvo)
total genus 74
structure length 273
sequence length 331
ec nomenclature
pdb deposition date 2015-03-26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 4z0dA01
2YILA 1HKYA 3ZWZA 3HMTA 3MKPA 4APMA 2Z8WA 1Z40A 2Q8AA 2YIOA 2Z8VA 3HMRA 4R1AA 5CP9A 5CS3A 2Y8RA 4Z0EA 3SP8A 3SRJA 3ZLEA 5CS5A 1W8KA 1I8NA 2HGFA 4APLA 4R19A 2X2ZA 5CT3A 5CS9A 5I25A 2LL3A 4IUAA 3SRIA 4UAOA 2YIPA 4Z0DA 2J8JA 5CSQA 1BHTA 4R1CA 4A5TS 5CS1A 3HMSA 1GMOA 2QJ4A 1NK1A 4UV6A 2Q8BA 1GMNA 4Z0FA 1YXEA 2F83A 2QJ2A 2K13X 4DURA 2LL4M 5COEA 4R1BA 5EOKA 4Z09A 5EODA 2J8LA 1W81A 1GP9A 3HN4A 5CT2A 5CT1A
chains in the Genus database with same CATH superfamily
2YILA 1HKYA 3ZWZA 3HMTA 4YIZA 3MKPA 4APMA 2Z8WA 1Z40A 2Q8AA 2YIOA 2Z8VA 3HMRA 4R1AA 5CP9A 5CS3A 2Y8RA 4Z0EA 3SP8A 3SRJA 3ZLEA 5CS5A 1W8KA 1I8NA 2HGFA 4APLA 4R19A 2X2ZA 5CT3A 5CS9A 5I25A 2LL3A 4IUAA 3SRIA 4UAOA 2YIPA 4YIVA 4Z0DA 2J8JA 5CSQA 1BHTA 4R1CA 4A5TS 5CS1A 3HMSA 1GMOA 2QJ4A 1NK1A 4UV6A 2Q8BA 1GMNA 4Z0FA 1YXEA 2F83A 2KL5A 2K13X 2QJ2A 4DURA 2LL4M 5COEA 4R1BA 5EOKA 4Z09A 5EODA 2J8LA 1W81A 1GP9A 3HN4A 5CT2A 5CT1A
chains in the Genus database with same CATH topology
2YILA 1HKYA 3ZWZA 3HMTA 4YIZA 3MKPA 4APMA 2Z8WA 1Z40A 2Q8AA 2YIOA 2Z8VA 3HMRA 4R1AA 5CP9A 5CS3A 2Y8RA 4Z0EA 3SP8A 3SRJA 3ZLEA 5CS5A 1W8KA 1I8NA 2HGFA 4APLA 4R19A 2X2ZA 5CT3A 5CS9A 5I25A 2LL3A 4IUAA 3SRIA 4UAOA 2YIPA 4YIVA 4Z0DA 2J8JA 5CSQA 1BHTA 4R1CA 4A5TS 5CS1A 3HMSA 1GMOA 2QJ4A 1NK1A 4UV6A 2Q8BA 1GMNA 4Z0FA 1YXEA 2F83A 2KL5A 2K13X 2QJ2A 4DURA 2LL4M 5COEA 4R1BA 5EOKA 4Z09A 5EODA 2J8LA 1W81A 1GP9A 3HN4A 5CT2A 5CT1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YIL A;  1HKY A;  3ZWZ A;  3HMT A;  3MKP A;  4APM A;  2Z8W A;  1Z40 A;  2Q8A A;  2YIO A;  2Z8V A;  3HMR A;  4R1A A;  5CP9 A;  5CS3 A;  2Y8R A;  4Z0E A;  3SP8 A;  3SRJ A;  3ZLE A;  5CS5 A;  1W8K A;  1I8N A;  2HGF A;  4APL A;  4R19 A;  2X2Z A;  5CT3 A;  5CS9 A;  5I25 A;  2LL3 A;  4IUA A;  3SRI A;  4UAO A;  2YIP A;  4Z0D A;  2J8J A;  5CSQ A;  1BHT A;  4R1C A;  4A5T S;  5CS1 A;  3HMS A;  1GMO A;  2QJ4 A;  1NK1 A;  4UV6 A;  2Q8B A;  1GMN A;  4Z0F A;  1YXE A;  2F83 A;  2QJ2 A;  2K13 X;  4DUR A;  2LL4 M;  5COE A;  4R1B A;  5EOK A;  4Z09 A;  5EOD A;  2J8L A;  1W81 A;  1GP9 A;  3HN4 A;  5CT2 A;  5CT1 A; 
#chains in the Genus database with same CATH topology
 2YIL A;  1HKY A;  3ZWZ A;  3HMT A;  4YIZ A;  3MKP A;  4APM A;  2Z8W A;  1Z40 A;  2Q8A A;  2YIO A;  2Z8V A;  3HMR A;  4R1A A;  5CP9 A;  5CS3 A;  2Y8R A;  4Z0E A;  3SP8 A;  3SRJ A;  3ZLE A;  5CS5 A;  1W8K A;  1I8N A;  2HGF A;  4APL A;  4R19 A;  2X2Z A;  5CT3 A;  5CS9 A;  5I25 A;  2LL3 A;  4IUA A;  3SRI A;  4UAO A;  2YIP A;  4YIV A;  4Z0D A;  2J8J A;  5CSQ A;  1BHT A;  4R1C A;  4A5T S;  5CS1 A;  3HMS A;  1GMO A;  2QJ4 A;  1NK1 A;  4UV6 A;  2Q8B A;  1GMN A;  4Z0F A;  1YXE A;  2F83 A;  2KL5 A;  2K13 X;  2QJ2 A;  4DUR A;  2LL4 M;  5COE A;  4R1B A;  5EOK A;  4Z09 A;  5EOD A;  2J8L A;  1W81 A;  1GP9 A;  3HN4 A;  5CT2 A;  5CT1 A; 
#chains in the Genus database with same CATH homology
 2YIL A;  1HKY A;  3ZWZ A;  3HMT A;  4YIZ A;  3MKP A;  4APM A;  2Z8W A;  1Z40 A;  2Q8A A;  2YIO A;  2Z8V A;  3HMR A;  4R1A A;  5CP9 A;  5CS3 A;  2Y8R A;  4Z0E A;  3SP8 A;  3SRJ A;  3ZLE A;  5CS5 A;  1W8K A;  1I8N A;  2HGF A;  4APL A;  4R19 A;  2X2Z A;  5CT3 A;  5CS9 A;  5I25 A;  2LL3 A;  4IUA A;  3SRI A;  4UAO A;  2YIP A;  4YIV A;  4Z0D A;  2J8J A;  5CSQ A;  1BHT A;  4R1C A;  4A5T S;  5CS1 A;  3HMS A;  1GMO A;  2QJ4 A;  1NK1 A;  4UV6 A;  2Q8B A;  1GMN A;  4Z0F A;  1YXE A;  2F83 A;  2KL5 A;  2K13 X;  2QJ2 A;  4DUR A;  2LL4 M;  5COE A;  4R1B A;  5EOK A;  4Z09 A;  5EOD A;  2J8L A;  1W81 A;  1GP9 A;  3HN4 A;  5CT2 A;  5CT1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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