3WDEA

Mutant n-terminal domain of mycobacterium tuberculosis clpc1, f80y, bound to cyclomarin a
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
147
structure length
147
Chain Sequence
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPYTPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Chaperone/antimicrobial protein
molecule keywords Probable ATP-dependent Clp protease ATP-binding subunit
publication title Structural basis of mycobacterial inhibition by cyclomarin A
pubmed doi rcsb
source organism Mycobacterium tuberculosis
total genus 60
structure length 147
sequence length 147
ec nomenclature
pdb deposition date 2013-06-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02861 Clp_N Clp amino terminal domain, pathogenicity island component
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1780.10 Mainly Alpha Orthogonal Bundle Double Clp-N motif Clp, N-terminal domain 3wdeA00
1R6CX 3FESA 4IODA 2K77A 1KSFX 1LZWB 2Y1QA 3ZRIA 4P15A 3WDEA 1K6KA 1R6OA 1R6QA 3WDDA 3WDBA 3FH2A 1MBXA 4UQWA 1MBVA 1R6BX 3ZRJA 1QVRA 4HH5A 4IRFA 1MG9B 4Y0CA 5HBNA 4HH6A 3WDCA 4Y0BA 1MBUA 1KHYA 2Y1RA 3PXGA 5GUIA
chains in the Genus database with same CATH superfamily
1R6CX 3FESA 4IODA 2K77A 1KSFX 1LZWB 2Y1QA 3ZRIA 4P15A 3WDEA 1K6KA 1R6OA 1R6QA 3WDDA 3WDBA 3FH2A 1MBXA 4UQWA 1MBVA 1R6BX 3ZRJA 1QVRA 4HH5A 4IRFA 1MG9B 4Y0CA 5HBNA 4HH6A 3WDCA 4Y0BA 1MBUA 1KHYA 2Y1RA 3PXGA 5GUIA
chains in the Genus database with same CATH topology
1R6CX 3FESA 4IODA 2K77A 1KSFX 1LZWB 2Y1QA 3ZRIA 4P15A 3WDEA 1K6KA 1R6OA 1R6QA 3WDDA 3WDBA 3FH2A 1MBXA 4UQWA 1MBVA 1R6BX 3ZRJA 1QVRA 4HH5A 4IRFA 1MG9B 4Y0CA 5HBNA 4HH6A 3WDCA 4Y0BA 1MBUA 1KHYA 2Y1RA 3PXGA 5GUIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1R6C X;  3FES A;  4IOD A;  2K77 A;  1KSF X;  1LZW B;  2Y1Q A;  3ZRI A;  4P15 A;  3WDE A;  1K6K A;  1R6O A;  1R6Q A;  3WDD A;  3WDB A;  3FH2 A;  1MBX A;  4UQW A;  1MBV A;  1R6B X;  3ZRJ A;  1QVR A;  4HH5 A;  4IRF A;  1MG9 B;  4Y0C A;  5HBN A;  4HH6 A;  3WDC A;  4Y0B A;  1MBU A;  1KHY A;  2Y1R A;  3PXG A;  5GUI A; 
#chains in the Genus database with same CATH topology
 1R6C X;  3FES A;  4IOD A;  2K77 A;  1KSF X;  1LZW B;  2Y1Q A;  3ZRI A;  4P15 A;  3WDE A;  1K6K A;  1R6O A;  1R6Q A;  3WDD A;  3WDB A;  3FH2 A;  1MBX A;  4UQW A;  1MBV A;  1R6B X;  3ZRJ A;  1QVR A;  4HH5 A;  4IRF A;  1MG9 B;  4Y0C A;  5HBN A;  4HH6 A;  3WDC A;  4Y0B A;  1MBU A;  1KHY A;  2Y1R A;  3PXG A;  5GUI A; 
#chains in the Genus database with same CATH homology
 1R6C X;  3FES A;  4IOD A;  2K77 A;  1KSF X;  1LZW B;  2Y1Q A;  3ZRI A;  4P15 A;  3WDE A;  1K6K A;  1R6O A;  1R6Q A;  3WDD A;  3WDB A;  3FH2 A;  1MBX A;  4UQW A;  1MBV A;  1R6B X;  3ZRJ A;  1QVR A;  4HH5 A;  4IRF A;  1MG9 B;  4Y0C A;  5HBN A;  4HH6 A;  3WDC A;  4Y0B A;  1MBU A;  1KHY A;  2Y1R A;  3PXG A;  5GUI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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