4IRFA

Preliminary structural investigations of a malarial protein secretion system
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
145
structure length
145
Chain Sequence
QGKYLNRTINILNAGKNIAKSYGHNKLKPIHILSALAKSDYGSTLFKENNVNAANLKEYIDIALEQTRAGAPLDNKSKIVNSAEVKETLALAEAAANKYKSPKVDVEHLLSGLSNDELVNEIFNEVYLTDEAIKAILKRKFEKTL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Chaperone
molecule keywords MALARIAL CLPB2 ATPASE/HSP101 PROTEIN
publication title Structural mapping of the ClpB ATPases of Plasmodium falciparum: Targeting protein folding and secretion for antimalarial drug design.
pubmed doi rcsb
source organism Plasmodium falciparum
total genus 61
structure length 145
sequence length 145
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-01-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02861 Clp_N Clp amino terminal domain, pathogenicity island component
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1780.10 Mainly Alpha Orthogonal Bundle Double Clp-N motif Clp, N-terminal domain 4irfA00
1R6CX 4HH6A 5HBNA 1KHYA 3ZRJA 4HH5A 4Y0BA 3WDEA 1R6QA 1R6BX 3FH2A 4P15A 1R6OA 3WDDA 2Y1RA 1MBVA 4IRFA 3FESA 1MBUA 3PXGA 4IODA 1MG9B 3WDBA 5GUIA 4Y0CA 1KSFX 3ZRIA 1MBXA 1QVRA 3WDCA 4UQWA 2K77A 1LZWB 2Y1QA 1K6KA
chains in the Genus database with same CATH superfamily
1R6CX 4HH6A 5HBNA 1KHYA 3ZRJA 4HH5A 4Y0BA 3WDEA 1R6QA 1R6BX 3FH2A 4P15A 1R6OA 3WDDA 2Y1RA 1MBVA 4IRFA 3FESA 1MBUA 3PXGA 4IODA 1MG9B 3WDBA 5GUIA 4Y0CA 1KSFX 3ZRIA 1MBXA 1QVRA 3WDCA 4UQWA 2K77A 1LZWB 2Y1QA 1K6KA
chains in the Genus database with same CATH topology
1R6CX 4HH6A 5HBNA 1KHYA 3ZRJA 4HH5A 4Y0BA 3WDEA 1R6QA 1R6BX 3FH2A 4P15A 1R6OA 3WDDA 2Y1RA 1MBVA 4IRFA 3FESA 1MBUA 3PXGA 4IODA 1MG9B 3WDBA 5GUIA 4Y0CA 1KSFX 3ZRIA 1MBXA 1QVRA 3WDCA 4UQWA 2K77A 1LZWB 2Y1QA 1K6KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1R6C X;  4HH6 A;  5HBN A;  1KHY A;  3ZRJ A;  4HH5 A;  4Y0B A;  3WDE A;  1R6Q A;  1R6B X;  3FH2 A;  4P15 A;  1R6O A;  3WDD A;  2Y1R A;  1MBV A;  4IRF A;  3FES A;  1MBU A;  3PXG A;  4IOD A;  1MG9 B;  3WDB A;  5GUI A;  4Y0C A;  1KSF X;  3ZRI A;  1MBX A;  1QVR A;  3WDC A;  4UQW A;  2K77 A;  1LZW B;  2Y1Q A;  1K6K A; 
#chains in the Genus database with same CATH topology
 1R6C X;  4HH6 A;  5HBN A;  1KHY A;  3ZRJ A;  4HH5 A;  4Y0B A;  3WDE A;  1R6Q A;  1R6B X;  3FH2 A;  4P15 A;  1R6O A;  3WDD A;  2Y1R A;  1MBV A;  4IRF A;  3FES A;  1MBU A;  3PXG A;  4IOD A;  1MG9 B;  3WDB A;  5GUI A;  4Y0C A;  1KSF X;  3ZRI A;  1MBX A;  1QVR A;  3WDC A;  4UQW A;  2K77 A;  1LZW B;  2Y1Q A;  1K6K A; 
#chains in the Genus database with same CATH homology
 1R6C X;  4HH6 A;  5HBN A;  1KHY A;  3ZRJ A;  4HH5 A;  4Y0B A;  3WDE A;  1R6Q A;  1R6B X;  3FH2 A;  4P15 A;  1R6O A;  3WDD A;  2Y1R A;  1MBV A;  4IRF A;  3FES A;  1MBU A;  3PXG A;  4IOD A;  1MG9 B;  3WDB A;  5GUI A;  4Y0C A;  1KSF X;  3ZRI A;  1MBX A;  1QVR A;  3WDC A;  4UQW A;  2K77 A;  1LZW B;  2Y1Q A;  1K6K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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