4WLWA

Crystal structure of the ag(i) (activator) form of e. coli cuer, a copper efflux regulator, bound to copa promoter dna
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
130
structure length
130
Chain Sequence
MNISDVAKITGLTSKAIRFYEEKGLVTPPMRSENGYRTYTQQHLNELTLLRQARQVGFNLEESGELVNLFNDPQRHSADVKRRTLEKVAEIERHIEELQSMRDQLLALANACPGDDSADCPIIENLSGCC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription/dna
molecule keywords HTH-type transcriptional regulator CueR
publication title TRANSCRIPTION. Allosteric transcriptional regulation via changes in the overall topology of the core promoter.
pubmed doi rcsb
source organism Escherichia coli
total genus 46
structure length 130
sequence length 130
ec nomenclature
pdb deposition date 2014-10-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00376 MerR MerR family regulatory protein
A PF09278 MerR-DNA-bind MerR, DNA binding
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1660.10 Mainly Alpha Orthogonal Bundle Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 4wlwA00
3GP4A 4R22B 3D71A 1R8EA 5D8CA 5I41B 1Q09A 3D6ZA 4WLWA 3HH0A 2JMLA 4R4EA 1JBGA 3D6YA 3D70A 5E01A 1EXIA 2ZHGA 3Q1MA 3Q5SA 3UCSA 5I44A 2DG6A 1Q05A 5D90A 1Q07A 4R24B 1EXJA 2VZ4A 2ZHHA 3IAOA 3Q3DA 1Q06A 3Q2YA 3Q5PA 1Q08A 1R8DA 3GPVA 4WLSA 4J2NA 3Q5RA 3QAOA 1Q0AA
chains in the Genus database with same CATH superfamily
3GP4A 3EZ6A 4R22B 3D71A 1R8EA 5D8CA 5I41B 1Q09A 3D6ZA 1PM6A 1Y6UA 3HH0A 4WLWA 2JMLA 4R4EA 1JBGA 3D6YA 1RH6A 3D70A 5E01A 4LHFA 1EXIA 2ZHGA 3Q1MA 3EZ7A 3Q5SA 3EZFA 3UCSA 4DCZA 2DG6A 1Q05A 5I44A 5D90A 2KVVA 1Q07A 4R24B 3EZ2A 1EXJA 2OG0A 2VZ4A 2ZHHA 3IAOA 3Q3DA 2IEFA 1Q06A 3Q2YA 3Q5PA 1Q08A 1R8DA 3EZ9A 3GPVA 4WLSA 4J2NA 3Q5RA 1LX8A 3QAOA 1Q0AA
chains in the Genus database with same CATH topology
3GP4A 3EZ6A 4R22B 3D71A 1R8EA 5D8CA 5I41B 1Q09A 3D6ZA 1PM6A 1Y6UA 3HH0A 4WLWA 2JMLA 4R4EA 1JBGA 3D6YA 1RH6A 3D70A 5E01A 4LHFA 1EXIA 2ZHGA 3Q1MA 3EZ7A 3Q5SA 3EZFA 3UCSA 4DCZA 2DG6A 1Q05A 5I44A 5D90A 2KVVA 1Q07A 4R24B 3EZ2A 1EXJA 2OG0A 2VZ4A 2ZHHA 3IAOA 3Q3DA 2IEFA 1Q06A 3Q2YA 3Q5PA 1Q08A 1R8DA 3EZ9A 3GPVA 4WLSA 4J2NA 3Q5RA 1LX8A 3QAOA 1Q0AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GP4 A;  4R22 B;  3D71 A;  1R8E A;  5D8C A;  5I41 B;  1Q09 A;  3D6Z A;  4WLW A;  3HH0 A;  2JML A;  4R4E A;  1JBG A;  3D6Y A;  3D70 A;  5E01 A;  1EXI A;  2ZHG A;  3Q1M A;  3Q5S A;  3UCS A;  5I44 A;  2DG6 A;  1Q05 A;  5D90 A;  1Q07 A;  4R24 B;  1EXJ A;  2VZ4 A;  2ZHH A;  3IAO A;  3Q3D A;  1Q06 A;  3Q2Y A;  3Q5P A;  1Q08 A;  1R8D A;  3GPV A;  4WLS A;  4J2N A;  3Q5R A;  3QAO A;  1Q0A A; 
#chains in the Genus database with same CATH topology
 3GP4 A;  3EZ6 A;  4R22 B;  3D71 A;  1R8E A;  5D8C A;  5I41 B;  1Q09 A;  3D6Z A;  1PM6 A;  1Y6U A;  3HH0 A;  4WLW A;  2JML A;  4R4E A;  1JBG A;  3D6Y A;  1RH6 A;  3D70 A;  5E01 A;  4LHF A;  1EXI A;  2ZHG A;  3Q1M A;  3EZ7 A;  3Q5S A;  3EZF A;  3UCS A;  4DCZ A;  2DG6 A;  1Q05 A;  5I44 A;  5D90 A;  2KVV A;  1Q07 A;  4R24 B;  3EZ2 A;  1EXJ A;  2OG0 A;  2VZ4 A;  2ZHH A;  3IAO A;  3Q3D A;  2IEF A;  1Q06 A;  3Q2Y A;  3Q5P A;  1Q08 A;  1R8D A;  3EZ9 A;  3GPV A;  4WLS A;  4J2N A;  3Q5R A;  1LX8 A;  3QAO A;  1Q0A A; 
#chains in the Genus database with same CATH homology
 3GP4 A;  3EZ6 A;  4R22 B;  3D71 A;  1R8E A;  5D8C A;  5I41 B;  1Q09 A;  3D6Z A;  1PM6 A;  1Y6U A;  3HH0 A;  4WLW A;  2JML A;  4R4E A;  1JBG A;  3D6Y A;  1RH6 A;  3D70 A;  5E01 A;  4LHF A;  1EXI A;  2ZHG A;  3Q1M A;  3EZ7 A;  3Q5S A;  3EZF A;  3UCS A;  4DCZ A;  2DG6 A;  1Q05 A;  5I44 A;  5D90 A;  2KVV A;  1Q07 A;  4R24 B;  3EZ2 A;  1EXJ A;  2OG0 A;  2VZ4 A;  2ZHH A;  3IAO A;  3Q3D A;  2IEF A;  1Q06 A;  3Q2Y A;  3Q5P A;  1Q08 A;  1R8D A;  3EZ9 A;  3GPV A;  4WLS A;  4J2N A;  3Q5R A;  1LX8 A;  3QAO A;  1Q0A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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