4CDDB

Human dpp1 in complex with (2s)-n-((1s)-1-cyano-2-(4-(4-cyanophenyl) phenyl)ethyl)piperidine-2-carboxamide
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
162
structure length
162
Chain Sequence
HLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSCSQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYVGGFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIYHHT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
molecule keywords DIPEPTIDYL PEPTIDASE 1 EXCLUSION DOMAIN CHAIN
publication title Cathepsin C Inhibitors: Property Optimization and Identification of a Clinical Candidate.
pubmed doi rcsb
source organism Homo sapiens
total genus 42
structure length 162
sequence length 162
chains with identical sequence E
ec nomenclature ec 3.4.14.1: Dipeptidyl-peptidase I.
pdb deposition date 2013-10-31
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 4cddB01
1JQPA 4YVAA 1CTEA 3DF0A 2PADA 1AIMA 1Y08A 1PE6A 3N4CA 3BOWA 4N4ZA 3WXFA 3GCBA 2DC8A 2NQAA 4YYSA 4ZUXU 4QRXA 1CS8A 1CB5A 4XUIA 1YVBA 5CHTA 1ICFA 5PADA 3V6CA 2DC6A 3ERVA 1PPPA 3HHAA 1AYUA 2AVWA 5CVMA 1AYVA 3MHSA 2GHUA 9PAPA 1U9XA 1GMYA 2F1GA 1POPA 2P86A 2DJFB 3BCNA 1YT7A 1NL6A 4MZOA 3F5VA 2OZ2A 3KWZA 1TLOA 1K3BB 3CH3X 3H8CA 3KW9A 2XU1A 1TU6A 5CHVA 1IWDA 3QSDA 1YK7A 2G8EA 3P5VA 3H7DA 2ACTA 3K24A 1CVZA 1KHQA 2FRAA 1VSNA 1AU0A 2PNSA 2DCAA 2FRQA 3E1ZB 3K9MA 3HWNA 6PADA 4Q8GA 2FO5A 3CH2X 3MHHA 3CBJA 4P6EA 2DCBA 2B1NA 3S3QA 1BQIA 2NQGA 1QOLA 2AUZA 1PBHA 1S4VA 5JA7A 2XU4A 3IV2A 3S3RA 2CIOA 3OF9A 3KSEA 1EF7A 3KWBX 1F29A 2G6DA 1M6DA 4YYUA 4AXMA 4G54A 4FJCA 1MEMA 1PXVA 2HH5A 4BPVA 3IOQA 1CSBB 3IMAA 4MSXA 4W5CA 2YJBA 4PI3A 1SP4B 2YJ9A 4YYQA 4YYWA 2IPPB 2NQIA 3LFYA 4W5BA 2ATOA 1SNKA 1EWMA 3O1GA 2R6NA 1PCIA 1GECE 2P0RA 4WA6A 3LXSA 1FH0A 2HD5A 1KFXL 1MS6A 4X6IA 1TL9A 2PBHA 3K8UA 2DC9A 2DJGB 4OELA 5F02A 1KXRA 4QH6A 3C9EA 2OP3A 2R9MA 1GCBA 2R9OA 3BPFA 1U9WA 1MEGA 5K16A 8PCHA 2AIMA 2HHNA 2H7JA 1CQDA 7PCKA 4KLBA 3BC3A 4CDFB 2R9FA 4K7CA 4BSQA 1NQCA 1NB5A 1AYWA 2FQ9A 4RY2A 3H6SA 4QRGA 1CV8A 3IHPA 1BP4A 3HHIA 1BY8A 2E00A 3WXGA 3TNXA 1YK8A 2YJ8A 4QBBA 1Y4HA 3D6SA 3BPMA 3BWKA 3KFQA 3PW3A 2CB5A 2AYNA 1U9VA 3KKUA 3ZUAA 1U9QX 4W4UA 4BS5A 1ITOA 4Q8HA 1PADA 5EGWA 2FUDA 3V6EA 4YYRA 3OF8A 1PPOA 4X6HA 1O0EA 3U8EA 3HD3A 3IEJA 1EWOA 1NLJA 3PNRA 3P5UA 4XR7A 2HXZA 2JQFR 3MTNA 5EF4A 3N3GA 2AYOA 1PPNA 2XU5A 2BDZA 1THEA 4YYVA 3USVA 1YALA 3CBKA 2G7YA 1F2CA 3OISA 2ARYA 2FYEA 1NB3A 3M99A 2AU1A 4CDEB 2JQGR 1PIPA 3F75A 1STFE 1XKGA 5CVNB 2AUXA 1U5IA 1MHWA 4P6GA 1AECA 4CDCB 4PP1A 2OULA 2DCCA 3RVWA 4N8WA 2VHSA 4DMYA 4MZSA 1X9YA 1HUCB 3RVVA 2R9CA 1PPDA 2FTDA 1MIRA 3PDFA 2R9NA 4FK5A 1CPJA 4BS6A 2C0YA 1EWLA 2WBFX 4CDDB 3OVZA 2E03A 1KFUL 4N79A 4DMXA 4I05A 2PREA 2Y5BA 2O6XA 3OVXA 3NHEA 1ATKA 5FPWA 1AU3A 2GFOA 5CVOB 3N3KA 2F7DA 2E01A 1ME3A 1DF0A 3P5XA 2E02A 4AXLA 2DCDA 2G8JA 4I04A 3I3TA 1EWPA 2YJCA 3P5WA 2P7UA 1NPZA 3KX1A 4OEMA 1A6RA 4FIPA 1BGOA 3IUTA 4YV8A 1AU2A 3QJ3A 5J94A 3O0UA 2XU3A 5JH3A 1Q6KA 5A24A 2DZZA 1ME4A 1ZCMA 2VHFA 1MDWA 1QMYA 2DZYA 1CJLA 4BQVA 2NQDB 2DC7A 1QDQA 1GLOA 3H8BA 3H89A 1AU4A 2Y6EA 3MORA 1KHPA 3WXEA 2BDLA 4PP2E 1F2BA 4CZWA 4HWYA 4PADA 4QRVA 1F2AA 2B1MA 1DEUA 2AS8A 3RVXA 4I07A 1VJVA 3QT4A 3I06A 2IBIA 2YJ2A 4X6JA 3B79A 1QXPA 3PBHA 3AI8A 1ZIVA 2FT2A
chains in the Genus database with same CATH superfamily
1JQPA 2BU3A 1CTEA 4YVAA 3DF0A 2PADA 1AIMA 1Y08A 4RF1A 4RNAA 4D8IA 3E9SA 1PE6A 3N4CA 3BOWA 4N4ZA 3WXFA 3GCBA 2DC8A 2NQAA 4A5UA 4YYSA 4ZUXU 4QRXA 1CS8A 1CB5A 4XUIA 1YVBA 5CHTA 3B21A 1ICFA 5PADA 3V6CA 1DKIA 2DC6A 3ERVA 1PPPA 3HHAA 1AYUA 3PRMA 2AVWA 4BOSA 5CVMA 1AYVA 3MHSA 2GHUA 4BOQA 9PAPA 1U9XA 3C0RA 3PHXA 1GMYA 2F1GA 1POPA 2P86A 2DJFB 3BCNA 1YT7A 1NL6A 4MZOA 3F5VA 2OZ2A 3KWZA 1TLOA 1K3BB 3CH3X 3H8CA 3KW9A 2XU1A 1TU6A 5CHVA 2Z84A 1IWDA 3QSDA 1YK7A 2G8EA 4REZA 3P5VA 3H7DA 2ACTA 3K24A 1CVZA 1KHQA 2FRAA 1VSNA 1AU0A 2PNSA 2DCAA 2FRQA 3E1ZB 3K9MA 3HWNA 2AGAA 6PADA 4Q8GA 2FO5A 3CH2X 4BOUA 3MHHA 3CBJA 4IUMA 4P6EA 2DCBA 2JRIA 2B1NA 3S3QA 3TMPA 1BQIA 2NQGA 1QOLA 3PHWA 2AUZA 3ZNHA 1PBHA 1S4VA 5JA7A 2XU4A 3IV2A 3S3RA 2CIOA 3OF9A 3KSEA 1EF7A 4MI7A 3KWBX 1F29A 2G6DA 1M6DA 4YYUA 4AXMA 4IP3A 2J7QA 2JTCA 1MEMA 1PXVA 4FJCA 2HH5A 4G54A 4GUAA 4BPVA 3IOQA 3PSEA 1CSBB 3IMAA 4MSXA 4W5CA 2YJBA 3BBAA 4PI3A 1SP4B 2YJ9A 4YYQA 4YYWA 2IPPB 2NQIA 3LFYA 4W5BA 2ATOA 1SNKA 3PT2A 1EWMA 3O1GA 2R6NA 3MTVA 1PCIA 1GECE 2P0RA 4WA6A 3LXSA 1FH0A 2HD5A 1KFXL 1MS6A 4X6IA 1TL9A 2PBHA 3K8UA 2DC9A 2DJGB 4BOPA 4OELA 5F02A 5EZSA 1KXRA 4QH6A 3C9EA 2OP3A 2R9MA 3OQCA 1GCBA 2R9OA 4PT5A 4HXDB 3BPFA 1U9WA 1MEGA 5K16A 8PCHA 2AIMA 2HHNA 2H7JA 1CQDA 7PCKA 4KLBA 3BC3A 4CDFB 2R9FA 4K7CA 4BSQA 1NQCA 1UKFA 1NB5A 1AYWA 4D8BA 5E6JA 2FQ9A 4RY2A 3H6SA 4QRGA 1CV8A 3IHPA 1BP4A 3HHIA 4RKXA 1BY8A 2E00A 3IFUA 3WXGA 3TNXA 1YK8A 2YJ8A 4QBBA 1Y4HA 3D6SA 3BPMA 3BWKA 3KFQA 4P16A 3PW3A 2CB5A 2AYNA 1U9VA 3KKUA 3ZUAA 1U9QX 4W4UA 4BS5A 1ITOA 4Q8HA 1PADA 5EGWA 2FUDA 3V6EA 4YYRA 3OF8A 1PPOA 4X6HA 1O0EA 3U8EA 3PRPA 3HD3A 3IEJA 1EWOA 1NLJA 3PNRA 3P5UA 4XR7A 2HWKA 2HXZA 2JQFR 1YZBA 3MTNA 4D8EA 5EF4A 3N3GA 4WURA 2AYOA 1PPNA 2XU5A 2BDZA 3O65A 1THEA 4YYVA 3USVA 1YALA 3CBKA 2G7YA 1F2CA 3OISA 2ARYA 2FYEA 1NB3A 3M99A 2AU1A 4CDEB 2JQGR 1PIPA 3F75A 1STFE 1XKGA 5KO3A 3MP2A 5CVNB 2AUXA 1U5IA 4MM3B 1MHWA 4P6GA 1AECA 4CDCB 5JZEA 4PP1A 2OULA 2DCCA 3RVWA 4N8WA 2VHSA 4DMYA 4MZSA 1X9YA 1HUCB 3RVVA 2R9CA 1PPDA 2FTDA 1MIRA 3PDFA 2R9NA 4FK5A 1CPJA 4BS6A 3BB7A 2C0YA 1EWLA 2WBFX 4CDDB 3OVZA 2E03A 1KFUL 4N79A 4DMXA 4I05A 2PREA 2Y5BA 2O6XA 3OVXA 3NHEA 1ATKA 5FPWA 4R3DA 1AU3A 2GFOA 5CVOB 3N3KA 2F7DA 4M0WA 2E01A 1ME3A 1DF0A 3P5XA 2E02A 4AXLA 2DCDA 2G8JA 4I04A 3I3TA 3RNVA 1EWPA 2YJCA 3P5WA 2P7UA 1NPZA 3KX1A 4OEMA 2UZJA 1A6RA 3BY4A 3W30A 4FIPA 1BGOA 3W31A 3IUTA 4YV8A 1AU2A 3QJ3A 5J94A 3O0UA 2XU3A 4OW0A 4RF0A 5JH3A 4BOZA 1Q6KA 3MJ5A 5A24A 4ZTBA 5EZQA 2DZZA 1ME4A 1ZCMA 2VHFA 1MDWA 1QMYA 2DZYA 1CJLA 4BQVA 2NQDB 2DC7A 1QDQA 1GLOA 3H8BA 3H89A 2BTWA 1AU4A 2Y6EA 3MORA 1KHPA 4OVZA 4XZXA 3WXEA 2BDLA 2BTWB 4OVZB 4PP2E 1F2BA 1PVJA 4CZWA 4HWYA 4PADA 4QRVA 1F2AA 2B1MA 1DEUA 2AS8A 3RVXA 4I07A 2FE8A 2DOSA 1VJVA 3QT4A 3I06A 3TRKA 3PHUA 2IBIA 2YJ2A 4X6JA 3B79A 1QXPA 2J7QC 3PBHA 3AI8A 1ZIVA 2FT2A
chains in the Genus database with same CATH topology
1JQPA 4YVAA 1CTEA 3DF0A 2PADA 1AIMA 1Y08A 1PE6A 3N4CA 3BOWA 4N4ZA 3WXFA 3GCBA 2DC8A 2NQAA 4YYSA 4ZUXU 4QRXA 1CS8A 1W6FA 1CB5A 4XUIA 1YVBA 5CHTA 1ICFA 5PADA 3V6CA 3D9WA 2DC6A 3ERVA 1PPPA 3HHAA 1AYUA 2AVWA 5CVMA 1AYVA 3MHSA 2GHUA 9PAPA 1U9XA 4B55A 1GMYA 2F1GA 1POPA 2P86A 2DJFB 3BCNA 1YT7A 1NL6A 4MZOA 3F5VA 2OZ2A 3KWZA 1TLOA 1K3BB 3CH3X 3H8CA 3KW9A 4GUZA 2XU1A 1TU6A 5CHVA 1IWDA 3QSDA 1YK7A 2G8EA 3P5VA 3H7DA 2ACTA 3K24A 1CVZA 1KHQA 2FRAA 1VSNA 1W5RA 1AU0A 2PNSA 2DCAA 2FRQA 3E1ZB 3K9MA 3HWNA 6PADA 4Q8GA 2FO5A 3CH2X 3MHHA 3CBJA 4P6EA 2DCBA 2B1NA 3S3QA 1BQIA 2NQGA 1QOLA 2AUZA 1PBHA 1S4VA 5JA7A 2XU4A 3IV2A 3S3RA 2CIOA 3OF9A 3KSEA 1EF7A 3KWBX 1F29A 2G6DA 1M6DA 4YYUA 4AXMA 4G54A 4FJCA 1MEMA 1PXVA 2HH5A 4BPVA 3IOQA 1CSBB 3IMAA 4MSXA 4W5CA 2YJBA 4PI3A 1SP4B 2YJ9A 4YYQA 4YYWA 2IPPB 2NQIA 3LFYA 4W5BA 2ATOA 1SNKA 1EWMA 3O1GA 2R6NA 1PCIA 1GECE 2P0RA 1E2TA 4WA6A 3LXSA 1FH0A 2HD5A 1KFXL 1MS6A 4X6IA 1TL9A 2PBHA 3K8UA 2DC9A 2DJGB 4OELA 1GX3A 5F02A 1KXRA 4QH6A 3C9EA 2OP3A 2R9MA 1GCBA 2R9OA 3BPFA 1U9WA 1MEGA 5K16A 8PCHA 2AIMA 2HHNA 2H7JA 1CQDA 7PCKA 4KLBA 3BC3A 4CDFB 2R9FA 4K7CA 4BSQA 1NQCA 1NB5A 1AYWA 4BGFA 2FQ9A 4RY2A 3H6SA 4QRGA 1CV8A 3IHPA 1BP4A 3HHIA 1BY8A 2E00A 3WXGA 3TNXA 1YK8A 2YJ8A 4QBBA 1Y4HA 3D6SA 3BPMA 3BWKA 3KFQA 3PW3A 2CB5A 4C5PA 2AYNA 1U9VA 3KKUA 3ZUAA 1U9QX 4W4UA 4BS5A 1ITOA 4Q8HA 1PADA 5EGWA 2FUDA 3V6EA 4NV8A 4YYRA 3OF8A 1PPOA 4X6HA 1O0EA 3U8EA 3HD3A 3IEJA 1EWOA 1NLJA 3PNRA 3P5UA 4XR7A 2HXZA 2JQFR 3MTNA 5EF4A 3N3GA 2AYOA 1PPNA 2XU5A 2BDZA 1THEA 4YYVA 3USVA 1YALA 3CBKA 2G7YA 1F2CA 2VFCA 3OISA 1W4TA 2VFBA 2ARYA 2FYEA 1NB3A 3M99A 2AU1A 4CDEB 2JQGR 1PIPA 3F75A 1STFE 1XKGA 5CVNB 2AUXA 1U5IA 1MHWA 4P6GA 1AECA 4CDCB 4PP1A 2OULA 2DCCA 3RVWA 4N8WA 2VHSA 4DMYA 4MZSA 1X9YA 1HUCB 3RVVA 2R9CA 1PPDA 2FTDA 1MIRA 3PDFA 2R9NA 4FK5A 1CPJA 4BS6A 2C0YA 1EWLA 2WBFX 4CDDB 3OVZA 2E03A 1KFUL 4N79A 4DMXA 4I05A 2PREA 2Y5BA 2O6XA 3OVXA 3NHEA 1ATKA 5FPWA 1AU3A 2GFOA 5CVOB 3N3KA 2F7DA 2E01A 1ME3A 1DF0A 3P5XA 2E02A 4AXLA 2DCDA 2G8JA 4I04A 3I3TA 1EWPA 2YJCA 3P5WA 2P7UA 1NPZA 3KX1A 4OEMA 1A6RA 4FIPA 1BGOA 3IUTA 4YV8A 1AU2A 3QJ3A 5J94A 3O0UA 2BSZA 2XU3A 5JH3A 1Q6KA 5A24A 2DZZA 1ME4A 1ZCMA 2VHFA 1MDWA 1QMYA 2DZYA 1CJLA 4BQVA 2NQDB 2DC7A 1QDQA 1GLOA 3H8BA 3H89A 1AU4A 2Y6EA 3MORA 1KHPA 3WXEA 2BDLA 4PP2E 1F2BA 4CZWA 4HWYA 4PADA 4QRVA 1F2AA 2B1MA 1DEUA 2AS8A 3RVXA 4I07A 1VJVA 3QT4A 3I06A 2IBIA 2YJ2A 4X6JA 3B79A 1QXPA 3PBHA 3AI8A 1ZIVA 2FT2A 4NV7A 3LTWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JQP A;  4YVA A;  1CTE A;  3DF0 A;  2PAD A;  1AIM A;  1Y08 A;  1PE6 A;  3N4C A;  3BOW A;  4N4Z A;  3WXF A;  3GCB A;  2DC8 A;  2NQA A;  4YYS A;  4ZUX U;  4QRX A;  1CS8 A;  1CB5 A;  4XUI A;  1YVB A;  5CHT A;  1ICF A;  5PAD A;  3V6C A;  2DC6 A;  3ERV A;  1PPP A;  3HHA A;  1AYU A;  2AVW A;  5CVM A;  1AYV A;  3MHS A;  2GHU A;  9PAP A;  1U9X A;  1GMY A;  2F1G A;  1POP A;  2P86 A;  2DJF B;  3BCN A;  1YT7 A;  1NL6 A;  4MZO A;  3F5V A;  2OZ2 A;  3KWZ A;  1TLO A;  1K3B B;  3CH3 X;  3H8C A;  3KW9 A;  2XU1 A;  1TU6 A;  5CHV A;  1IWD A;  3QSD A;  1YK7 A;  2G8E A;  3P5V A;  3H7D A;  2ACT A;  3K24 A;  1CVZ A;  1KHQ A;  2FRA A;  1VSN A;  1AU0 A;  2PNS A;  2DCA A;  2FRQ A;  3E1Z B;  3K9M A;  3HWN A;  6PAD A;  4Q8G A;  2FO5 A;  3CH2 X;  3MHH A;  3CBJ A;  4P6E A;  2DCB A;  2B1N A;  3S3Q A;  1BQI A;  2NQG A;  1QOL A;  2AUZ A;  1PBH A;  1S4V A;  5JA7 A;  2XU4 A;  3IV2 A;  3S3R A;  2CIO A;  3OF9 A;  3KSE A;  1EF7 A;  3KWB X;  1F29 A;  2G6D A;  1M6D A;  4YYU A;  4AXM A;  4G54 A;  4FJC A;  1MEM A;  1PXV A;  2HH5 A;  4BPV A;  3IOQ A;  1CSB B;  3IMA A;  4MSX A;  4W5C A;  2YJB A;  4PI3 A;  1SP4 B;  2YJ9 A;  4YYQ A;  4YYW A;  2IPP B;  2NQI A;  3LFY A;  4W5B A;  2ATO A;  1SNK A;  1EWM A;  3O1G A;  2R6N A;  1PCI A;  1GEC E;  2P0R A;  4WA6 A;  3LXS A;  1FH0 A;  2HD5 A;  1KFX L;  1MS6 A;  4X6I A;  1TL9 A;  2PBH A;  3K8U A;  2DC9 A;  2DJG B;  4OEL A;  5F02 A;  1KXR A;  4QH6 A;  3C9E A;  2OP3 A;  2R9M A;  1GCB A;  2R9O A;  3BPF A;  1U9W A;  1MEG A;  5K16 A;  8PCH A;  2AIM A;  2HHN A;  2H7J A;  1CQD A;  7PCK A;  4KLB A;  3BC3 A;  4CDF B;  2R9F A;  4K7C A;  4BSQ A;  1NQC A;  1NB5 A;  1AYW A;  2FQ9 A;  4RY2 A;  3H6S A;  4QRG A;  1CV8 A;  3IHP A;  1BP4 A;  3HHI A;  1BY8 A;  2E00 A;  3WXG A;  3TNX A;  1YK8 A;  2YJ8 A;  4QBB A;  1Y4H A;  3D6S A;  3BPM A;  3BWK A;  3KFQ A;  3PW3 A;  2CB5 A;  2AYN A;  1U9V A;  3KKU A;  3ZUA A;  1U9Q X;  4W4U A;  4BS5 A;  1ITO A;  4Q8H A;  1PAD A;  5EGW A;  2FUD A;  3V6E A;  4YYR A;  3OF8 A;  1PPO A;  4X6H A;  1O0E A;  3U8E A;  3HD3 A;  3IEJ A;  1EWO A;  1NLJ A;  3PNR A;  3P5U A;  4XR7 A;  2HXZ A;  2JQF R;  3MTN A;  5EF4 A;  3N3G A;  2AYO A;  1PPN A;  2XU5 A;  2BDZ A;  1THE A;  4YYV A;  3USV A;  1YAL A;  3CBK A;  2G7Y A;  1F2C A;  3OIS A;  2ARY A;  2FYE A;  1NB3 A;  3M99 A;  2AU1 A;  4CDE B;  2JQG R;  1PIP A;  3F75 A;  1STF E;  1XKG A;  5CVN B;  2AUX A;  1U5I A;  1MHW A;  4P6G A;  1AEC A;  4CDC B;  4PP1 A;  2OUL A;  2DCC A;  3RVW A;  4N8W A;  2VHS A;  4DMY A;  4MZS A;  1X9Y A;  1HUC B;  3RVV A;  2R9C A;  1PPD A;  2FTD A;  1MIR A;  3PDF A;  2R9N A;  4FK5 A;  1CPJ A;  4BS6 A;  2C0Y A;  1EWL A;  2WBF X;  4CDD B;  3OVZ A;  2E03 A;  1KFU L;  4N79 A;  4DMX A;  4I05 A;  2PRE A;  2Y5B A;  2O6X A;  3OVX A;  3NHE A;  1ATK A;  5FPW A;  1AU3 A;  2GFO A;  5CVO B;  3N3K A;  2F7D A;  2E01 A;  1ME3 A;  1DF0 A;  3P5X A;  2E02 A;  4AXL A;  2DCD A;  2G8J A;  4I04 A;  3I3T A;  1EWP A;  2YJC A;  3P5W A;  2P7U A;  1NPZ A;  3KX1 A;  4OEM A;  1A6R A;  4FIP A;  1BGO A;  3IUT A;  4YV8 A;  1AU2 A;  3QJ3 A;  5J94 A;  3O0U A;  2XU3 A;  5JH3 A;  1Q6K A;  5A24 A;  2DZZ A;  1ME4 A;  1ZCM A;  2VHF A;  1MDW A;  1QMY A;  2DZY A;  1CJL A;  4BQV A;  2NQD B;  2DC7 A;  1QDQ A;  1GLO A;  3H8B A;  3H89 A;  1AU4 A;  2Y6E A;  3MOR A;  1KHP A;  3WXE A;  2BDL A;  4PP2 E;  1F2B A;  4CZW A;  4HWY A;  4PAD A;  4QRV A;  1F2A A;  2B1M A;  1DEU A;  2AS8 A;  3RVX A;  4I07 A;  1VJV A;  3QT4 A;  3I06 A;  2IBI A;  2YJ2 A;  4X6J A;  3B79 A;  1QXP A;  3PBH A;  3AI8 A;  1ZIV A;  2FT2 A; 
#chains in the Genus database with same CATH topology
 1JQP A;  2BU3 A;  1CTE A;  4YVA A;  3DF0 A;  2PAD A;  1AIM A;  1Y08 A;  4RF1 A;  4RNA A;  4D8I A;  3E9S A;  1PE6 A;  3N4C A;  3BOW A;  4N4Z A;  3WXF A;  3GCB A;  2DC8 A;  2NQA A;  4A5U A;  4YYS A;  4ZUX U;  4QRX A;  1CS8 A;  1CB5 A;  4XUI A;  1YVB A;  5CHT A;  3B21 A;  1ICF A;  5PAD A;  3V6C A;  1DKI A;  2DC6 A;  3ERV A;  1PPP A;  3HHA A;  1AYU A;  3PRM A;  2AVW A;  4BOS A;  5CVM A;  1AYV A;  3MHS A;  2GHU A;  4BOQ A;  9PAP A;  1U9X A;  3C0R A;  3PHX A;  1GMY A;  2F1G A;  1POP A;  2P86 A;  2DJF B;  3BCN A;  1YT7 A;  1NL6 A;  4MZO A;  3F5V A;  2OZ2 A;  3KWZ A;  1TLO A;  1K3B B;  3CH3 X;  3H8C A;  3KW9 A;  2XU1 A;  1TU6 A;  5CHV A;  2Z84 A;  1IWD A;  3QSD A;  1YK7 A;  2G8E A;  4REZ A;  3P5V A;  3H7D A;  2ACT A;  3K24 A;  1CVZ A;  1KHQ A;  2FRA A;  1VSN A;  1AU0 A;  2PNS A;  2DCA A;  2FRQ A;  3E1Z B;  3K9M A;  3HWN A;  2AGA A;  6PAD A;  4Q8G A;  2FO5 A;  3CH2 X;  4BOU A;  3MHH A;  3CBJ A;  4IUM A;  4P6E A;  2DCB A;  2JRI A;  2B1N A;  3S3Q A;  3TMP A;  1BQI A;  2NQG A;  1QOL A;  3PHW A;  2AUZ A;  3ZNH A;  1PBH A;  1S4V A;  5JA7 A;  2XU4 A;  3IV2 A;  3S3R A;  2CIO A;  3OF9 A;  3KSE A;  1EF7 A;  4MI7 A;  3KWB X;  1F29 A;  2G6D A;  1M6D A;  4YYU A;  4AXM A;  4IP3 A;  2J7Q A;  2JTC A;  1MEM A;  1PXV A;  4FJC A;  2HH5 A;  4G54 A;  4GUA A;  4BPV A;  3IOQ A;  3PSE A;  1CSB B;  3IMA A;  4MSX A;  4W5C A;  2YJB A;  3BBA A;  4PI3 A;  1SP4 B;  2YJ9 A;  4YYQ A;  4YYW A;  2IPP B;  2NQI A;  3LFY A;  4W5B A;  2ATO A;  1SNK A;  3PT2 A;  1EWM A;  3O1G A;  2R6N A;  3MTV A;  1PCI A;  1GEC E;  2P0R A;  4WA6 A;  3LXS A;  1FH0 A;  2HD5 A;  1KFX L;  1MS6 A;  4X6I A;  1TL9 A;  2PBH A;  3K8U A;  2DC9 A;  2DJG B;  4BOP A;  4OEL A;  5F02 A;  5EZS A;  1KXR A;  4QH6 A;  3C9E A;  2OP3 A;  2R9M A;  3OQC A;  1GCB A;  2R9O A;  4PT5 A;  4HXD B;  3BPF A;  1U9W A;  1MEG A;  5K16 A;  8PCH A;  2AIM A;  2HHN A;  2H7J A;  1CQD A;  7PCK A;  4KLB A;  3BC3 A;  4CDF B;  2R9F A;  4K7C A;  4BSQ A;  1NQC A;  1UKF A;  1NB5 A;  1AYW A;  4D8B A;  5E6J A;  2FQ9 A;  4RY2 A;  3H6S A;  4QRG A;  1CV8 A;  3IHP A;  1BP4 A;  3HHI A;  4RKX A;  1BY8 A;  2E00 A;  3IFU A;  3WXG A;  3TNX A;  1YK8 A;  2YJ8 A;  4QBB A;  1Y4H A;  3D6S A;  3BPM A;  3BWK A;  3KFQ A;  4P16 A;  3PW3 A;  2CB5 A;  2AYN A;  1U9V A;  3KKU A;  3ZUA A;  1U9Q X;  4W4U A;  4BS5 A;  1ITO A;  4Q8H A;  1PAD A;  5EGW A;  2FUD A;  3V6E A;  4YYR A;  3OF8 A;  1PPO A;  4X6H A;  1O0E A;  3U8E A;  3PRP A;  3HD3 A;  3IEJ A;  1EWO A;  1NLJ A;  3PNR A;  3P5U A;  4XR7 A;  2HWK A;  2HXZ A;  2JQF R;  1YZB A;  3MTN A;  4D8E A;  5EF4 A;  3N3G A;  4WUR A;  2AYO A;  1PPN A;  2XU5 A;  2BDZ A;  3O65 A;  1THE A;  4YYV A;  3USV A;  1YAL A;  3CBK A;  2G7Y A;  1F2C A;  3OIS A;  2ARY A;  2FYE A;  1NB3 A;  3M99 A;  2AU1 A;  4CDE B;  2JQG R;  1PIP A;  3F75 A;  1STF E;  1XKG A;  5KO3 A;  3MP2 A;  5CVN B;  2AUX A;  1U5I A;  4MM3 B;  1MHW A;  4P6G A;  1AEC A;  4CDC B;  5JZE A;  4PP1 A;  2OUL A;  2DCC A;  3RVW A;  4N8W A;  2VHS A;  4DMY A;  4MZS A;  1X9Y A;  1HUC B;  3RVV A;  2R9C A;  1PPD A;  2FTD A;  1MIR A;  3PDF A;  2R9N A;  4FK5 A;  1CPJ A;  4BS6 A;  3BB7 A;  2C0Y A;  1EWL A;  2WBF X;  4CDD B;  3OVZ A;  2E03 A;  1KFU L;  4N79 A;  4DMX A;  4I05 A;  2PRE A;  2Y5B A;  2O6X A;  3OVX A;  3NHE A;  1ATK A;  5FPW A;  4R3D A;  1AU3 A;  2GFO A;  5CVO B;  3N3K A;  2F7D A;  4M0W A;  2E01 A;  1ME3 A;  1DF0 A;  3P5X A;  2E02 A;  4AXL A;  2DCD A;  2G8J A;  4I04 A;  3I3T A;  3RNV A;  1EWP A;  2YJC A;  3P5W A;  2P7U A;  1NPZ A;  3KX1 A;  4OEM A;  2UZJ A;  1A6R A;  3BY4 A;  3W30 A;  4FIP A;  1BGO A;  3W31 A;  3IUT A;  4YV8 A;  1AU2 A;  3QJ3 A;  5J94 A;  3O0U A;  2XU3 A;  4OW0 A;  4RF0 A;  5JH3 A;  4BOZ A;  1Q6K A;  3MJ5 A;  5A24 A;  4ZTB A;  5EZQ A;  2DZZ A;  1ME4 A;  1ZCM A;  2VHF A;  1MDW A;  1QMY A;  2DZY A;  1CJL A;  4BQV A;  2NQD B;  2DC7 A;  1QDQ A;  1GLO A;  3H8B A;  3H89 A;  2BTW A;  1AU4 A;  2Y6E A;  3MOR A;  1KHP A;  4OVZ A;  4XZX A;  3WXE A;  2BDL A;  2BTW B;  4OVZ B;  4PP2 E;  1F2B A;  1PVJ A;  4CZW A;  4HWY A;  4PAD A;  4QRV A;  1F2A A;  2B1M A;  1DEU A;  2AS8 A;  3RVX A;  4I07 A;  2FE8 A;  2DOS A;  1VJV A;  3QT4 A;  3I06 A;  3TRK A;  3PHU A;  2IBI A;  2YJ2 A;  4X6J A;  3B79 A;  1QXP A;  2J7Q C;  3PBH A;  3AI8 A;  1ZIV A;  2FT2 A; 
#chains in the Genus database with same CATH homology
 1JQP A;  4YVA A;  1CTE A;  3DF0 A;  2PAD A;  1AIM A;  1Y08 A;  1PE6 A;  3N4C A;  3BOW A;  4N4Z A;  3WXF A;  3GCB A;  2DC8 A;  2NQA A;  4YYS A;  4ZUX U;  4QRX A;  1CS8 A;  1W6F A;  1CB5 A;  4XUI A;  1YVB A;  5CHT A;  1ICF A;  5PAD A;  3V6C A;  3D9W A;  2DC6 A;  3ERV A;  1PPP A;  3HHA A;  1AYU A;  2AVW A;  5CVM A;  1AYV A;  3MHS A;  2GHU A;  9PAP A;  1U9X A;  4B55 A;  1GMY A;  2F1G A;  1POP A;  2P86 A;  2DJF B;  3BCN A;  1YT7 A;  1NL6 A;  4MZO A;  3F5V A;  2OZ2 A;  3KWZ A;  1TLO A;  1K3B B;  3CH3 X;  3H8C A;  3KW9 A;  4GUZ A;  2XU1 A;  1TU6 A;  5CHV A;  1IWD A;  3QSD A;  1YK7 A;  2G8E A;  3P5V A;  3H7D A;  2ACT A;  3K24 A;  1CVZ A;  1KHQ A;  2FRA A;  1VSN A;  1W5R A;  1AU0 A;  2PNS A;  2DCA A;  2FRQ A;  3E1Z B;  3K9M A;  3HWN A;  6PAD A;  4Q8G A;  2FO5 A;  3CH2 X;  3MHH A;  3CBJ A;  4P6E A;  2DCB A;  2B1N A;  3S3Q A;  1BQI A;  2NQG A;  1QOL A;  2AUZ A;  1PBH A;  1S4V A;  5JA7 A;  2XU4 A;  3IV2 A;  3S3R A;  2CIO A;  3OF9 A;  3KSE A;  1EF7 A;  3KWB X;  1F29 A;  2G6D A;  1M6D A;  4YYU A;  4AXM A;  4G54 A;  4FJC A;  1MEM A;  1PXV A;  2HH5 A;  4BPV A;  3IOQ A;  1CSB B;  3IMA A;  4MSX A;  4W5C A;  2YJB A;  4PI3 A;  1SP4 B;  2YJ9 A;  4YYQ A;  4YYW A;  2IPP B;  2NQI A;  3LFY A;  4W5B A;  2ATO A;  1SNK A;  1EWM A;  3O1G A;  2R6N A;  1PCI A;  1GEC E;  2P0R A;  1E2T A;  4WA6 A;  3LXS A;  1FH0 A;  2HD5 A;  1KFX L;  1MS6 A;  4X6I A;  1TL9 A;  2PBH A;  3K8U A;  2DC9 A;  2DJG B;  4OEL A;  1GX3 A;  5F02 A;  1KXR A;  4QH6 A;  3C9E A;  2OP3 A;  2R9M A;  1GCB A;  2R9O A;  3BPF A;  1U9W A;  1MEG A;  5K16 A;  8PCH A;  2AIM A;  2HHN A;  2H7J A;  1CQD A;  7PCK A;  4KLB A;  3BC3 A;  4CDF B;  2R9F A;  4K7C A;  4BSQ A;  1NQC A;  1NB5 A;  1AYW A;  4BGF A;  2FQ9 A;  4RY2 A;  3H6S A;  4QRG A;  1CV8 A;  3IHP A;  1BP4 A;  3HHI A;  1BY8 A;  2E00 A;  3WXG A;  3TNX A;  1YK8 A;  2YJ8 A;  4QBB A;  1Y4H A;  3D6S A;  3BPM A;  3BWK A;  3KFQ A;  3PW3 A;  2CB5 A;  4C5P A;  2AYN A;  1U9V A;  3KKU A;  3ZUA A;  1U9Q X;  4W4U A;  4BS5 A;  1ITO A;  4Q8H A;  1PAD A;  5EGW A;  2FUD A;  3V6E A;  4NV8 A;  4YYR A;  3OF8 A;  1PPO A;  4X6H A;  1O0E A;  3U8E A;  3HD3 A;  3IEJ A;  1EWO A;  1NLJ A;  3PNR A;  3P5U A;  4XR7 A;  2HXZ A;  2JQF R;  3MTN A;  5EF4 A;  3N3G A;  2AYO A;  1PPN A;  2XU5 A;  2BDZ A;  1THE A;  4YYV A;  3USV A;  1YAL A;  3CBK A;  2G7Y A;  1F2C A;  2VFC A;  3OIS A;  1W4T A;  2VFB A;  2ARY A;  2FYE A;  1NB3 A;  3M99 A;  2AU1 A;  4CDE B;  2JQG R;  1PIP A;  3F75 A;  1STF E;  1XKG A;  5CVN B;  2AUX A;  1U5I A;  1MHW A;  4P6G A;  1AEC A;  4CDC B;  4PP1 A;  2OUL A;  2DCC A;  3RVW A;  4N8W A;  2VHS A;  4DMY A;  4MZS A;  1X9Y A;  1HUC B;  3RVV A;  2R9C A;  1PPD A;  2FTD A;  1MIR A;  3PDF A;  2R9N A;  4FK5 A;  1CPJ A;  4BS6 A;  2C0Y A;  1EWL A;  2WBF X;  4CDD B;  3OVZ A;  2E03 A;  1KFU L;  4N79 A;  4DMX A;  4I05 A;  2PRE A;  2Y5B A;  2O6X A;  3OVX A;  3NHE A;  1ATK A;  5FPW A;  1AU3 A;  2GFO A;  5CVO B;  3N3K A;  2F7D A;  2E01 A;  1ME3 A;  1DF0 A;  3P5X A;  2E02 A;  4AXL A;  2DCD A;  2G8J A;  4I04 A;  3I3T A;  1EWP A;  2YJC A;  3P5W A;  2P7U A;  1NPZ A;  3KX1 A;  4OEM A;  1A6R A;  4FIP A;  1BGO A;  3IUT A;  4YV8 A;  1AU2 A;  3QJ3 A;  5J94 A;  3O0U A;  2BSZ A;  2XU3 A;  5JH3 A;  1Q6K A;  5A24 A;  2DZZ A;  1ME4 A;  1ZCM A;  2VHF A;  1MDW A;  1QMY A;  2DZY A;  1CJL A;  4BQV A;  2NQD B;  2DC7 A;  1QDQ A;  1GLO A;  3H8B A;  3H89 A;  1AU4 A;  2Y6E A;  3MOR A;  1KHP A;  3WXE A;  2BDL A;  4PP2 E;  1F2B A;  4CZW A;  4HWY A;  4PAD A;  4QRV A;  1F2A A;  2B1M A;  1DEU A;  2AS8 A;  3RVX A;  4I07 A;  1VJV A;  3QT4 A;  3I06 A;  2IBI A;  2YJ2 A;  4X6J A;  3B79 A;  1QXP A;  3PBH A;  3AI8 A;  1ZIV A;  2FT2 A;  4NV7 A;  3LTW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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