4Z0FA

Crystal structure of fvo strain plasmodium falciparum ama1 in complex with the ron2hp [phe2038(6cw)] peptide
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
332
structure length
278
Chain Sequence
GNPWTEYMAKYDIEEVHGSGIRVDLGEDAEVAGTQYRLPSGKCPVFGKGIIIENSNTTFLKPVATLKDGGFAFPPTNPLISPMTLNGMRDFYKNNEYVKNLDELTLCSRHAGNMNPDNKNSNYKYPAVYDYNDKKCHILYIAAQENNFCFRPAKDKLFENYTYLSKNVVDNWEEVCPRKNLENAKFGLWVDGNCEDIPHVNEFSANDLFECNKLVFELSASDQPKQYDRYKSHGKGYNWGNYNRETQKCEIFNVKPTCLINNSSYIATTALSHPIEVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cell invasion
molecule keywords Apical membrane antigen 1
publication title Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
pubmed doi rcsb
source organism Plasmodium falciparum vietnam oak-knoll (fvo)
total genus 75
structure length 278
sequence length 332
ec nomenclature
pdb deposition date 2015-03-26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 4z0fA01
4R1CA 4IUAA 5COEA 4UAOA 2LL4M 3SRJA 4R19A 4Z09A 3SRIA 5CS1A 1W81A 5CT3A 4DURA 3HN4A 3SP8A 5CS9A 4R1BA 2K13X 3HMTA 2F83A 3HMSA 5CP9A 1BHTA 3ZWZA 2YIPA 4A5TS 5CT1A 5I25A 1HKYA 3MKPA 4UV6A 1I8NA 5EOKA 2X2ZA 2QJ2A 2LL3A 4R1AA 5CS5A 1GP9A 2Z8WA 4Z0FA 1GMNA 3ZLEA 5EODA 3HMRA 1W8KA 1NK1A 5CSQA 1YXEA 2YILA 2J8JA 2J8LA 5CS3A 4APMA 1Z40A 1GMOA 5CT2A 4APLA 2Q8BA 2Q8AA 2YIOA 2HGFA 4Z0EA 2QJ4A 4Z0DA 2Y8RA 2Z8VA
chains in the Genus database with same CATH superfamily
4R1CA 4IUAA 5COEA 4UAOA 2LL4M 3SRJA 4R19A 4Z09A 3SRIA 5CS1A 4YIVA 1W81A 5CT3A 4DURA 3HN4A 3SP8A 5CS9A 4R1BA 2K13X 3HMTA 2F83A 3HMSA 5CP9A 1BHTA 3ZWZA 2YIPA 4A5TS 5CT1A 5I25A 1HKYA 3MKPA 4UV6A 1I8NA 5EOKA 2X2ZA 2QJ2A 2LL3A 4R1AA 5CS5A 1GP9A 2Z8WA 4Z0FA 1GMNA 3ZLEA 4YIZA 5EODA 3HMRA 1W8KA 1NK1A 5CSQA 1YXEA 2YILA 2J8JA 2J8LA 5CS3A 4APMA 1Z40A 1GMOA 5CT2A 4APLA 2Q8BA 2Q8AA 2KL5A 2YIOA 2HGFA 4Z0EA 2QJ4A 4Z0DA 2Y8RA 2Z8VA
chains in the Genus database with same CATH topology
4R1CA 4IUAA 5COEA 4UAOA 2LL4M 3SRJA 4R19A 4Z09A 3SRIA 5CS1A 4YIVA 1W81A 5CT3A 4DURA 3HN4A 3SP8A 5CS9A 4R1BA 2K13X 3HMTA 2F83A 3HMSA 5CP9A 1BHTA 3ZWZA 2YIPA 4A5TS 5CT1A 5I25A 1HKYA 3MKPA 4UV6A 1I8NA 5EOKA 2X2ZA 2QJ2A 2LL3A 4R1AA 5CS5A 1GP9A 2Z8WA 4Z0FA 1GMNA 3ZLEA 4YIZA 5EODA 3HMRA 1W8KA 1NK1A 5CSQA 1YXEA 2YILA 2J8JA 2J8LA 5CS3A 4APMA 1Z40A 1GMOA 5CT2A 4APLA 2Q8BA 2Q8AA 2KL5A 2YIOA 2HGFA 4Z0EA 2QJ4A 4Z0DA 2Y8RA 2Z8VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4R1C A;  4IUA A;  5COE A;  4UAO A;  2LL4 M;  3SRJ A;  4R19 A;  4Z09 A;  3SRI A;  5CS1 A;  1W81 A;  5CT3 A;  4DUR A;  3HN4 A;  3SP8 A;  5CS9 A;  4R1B A;  2K13 X;  3HMT A;  2F83 A;  3HMS A;  5CP9 A;  1BHT A;  3ZWZ A;  2YIP A;  4A5T S;  5CT1 A;  5I25 A;  1HKY A;  3MKP A;  4UV6 A;  1I8N A;  5EOK A;  2X2Z A;  2QJ2 A;  2LL3 A;  4R1A A;  5CS5 A;  1GP9 A;  2Z8W A;  4Z0F A;  1GMN A;  3ZLE A;  5EOD A;  3HMR A;  1W8K A;  1NK1 A;  5CSQ A;  1YXE A;  2YIL A;  2J8J A;  2J8L A;  5CS3 A;  4APM A;  1Z40 A;  1GMO A;  5CT2 A;  4APL A;  2Q8B A;  2Q8A A;  2YIO A;  2HGF A;  4Z0E A;  2QJ4 A;  4Z0D A;  2Y8R A;  2Z8V A; 
#chains in the Genus database with same CATH topology
 4R1C A;  4IUA A;  5COE A;  4UAO A;  2LL4 M;  3SRJ A;  4R19 A;  4Z09 A;  3SRI A;  5CS1 A;  4YIV A;  1W81 A;  5CT3 A;  4DUR A;  3HN4 A;  3SP8 A;  5CS9 A;  4R1B A;  2K13 X;  3HMT A;  2F83 A;  3HMS A;  5CP9 A;  1BHT A;  3ZWZ A;  2YIP A;  4A5T S;  5CT1 A;  5I25 A;  1HKY A;  3MKP A;  4UV6 A;  1I8N A;  5EOK A;  2X2Z A;  2QJ2 A;  2LL3 A;  4R1A A;  5CS5 A;  1GP9 A;  2Z8W A;  4Z0F A;  1GMN A;  3ZLE A;  4YIZ A;  5EOD A;  3HMR A;  1W8K A;  1NK1 A;  5CSQ A;  1YXE A;  2YIL A;  2J8J A;  2J8L A;  5CS3 A;  4APM A;  1Z40 A;  1GMO A;  5CT2 A;  4APL A;  2Q8B A;  2Q8A A;  2KL5 A;  2YIO A;  2HGF A;  4Z0E A;  2QJ4 A;  4Z0D A;  2Y8R A;  2Z8V A; 
#chains in the Genus database with same CATH homology
 4R1C A;  4IUA A;  5COE A;  4UAO A;  2LL4 M;  3SRJ A;  4R19 A;  4Z09 A;  3SRI A;  5CS1 A;  4YIV A;  1W81 A;  5CT3 A;  4DUR A;  3HN4 A;  3SP8 A;  5CS9 A;  4R1B A;  2K13 X;  3HMT A;  2F83 A;  3HMS A;  5CP9 A;  1BHT A;  3ZWZ A;  2YIP A;  4A5T S;  5CT1 A;  5I25 A;  1HKY A;  3MKP A;  4UV6 A;  1I8N A;  5EOK A;  2X2Z A;  2QJ2 A;  2LL3 A;  4R1A A;  5CS5 A;  1GP9 A;  2Z8W A;  4Z0F A;  1GMN A;  3ZLE A;  4YIZ A;  5EOD A;  3HMR A;  1W8K A;  1NK1 A;  5CSQ A;  1YXE A;  2YIL A;  2J8J A;  2J8L A;  5CS3 A;  4APM A;  1Z40 A;  1GMO A;  5CT2 A;  4APL A;  2Q8B A;  2Q8A A;  2KL5 A;  2YIO A;  2HGF A;  4Z0E A;  2QJ4 A;  4Z0D A;  2Y8R A;  2Z8V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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