5JXZA

A low magnesium structure of the isochorismate synthase, entc
Total Genus 115
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
115
sequence length
376
structure length
373
Chain Sequence
TLAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASATRSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Isomerase
molecule keywords Isochorismate synthase EntC
publication title An Open and Shut Case: The Interaction of Magnesium with MST Enzymes.
pubmed doi rcsb
source organism Escherichia coli o157:h7
total genus 115
structure length 373
sequence length 376
chains with identical sequence B
ec nomenclature ec 5.4.4.2: Isochorismate synthase.
pdb deposition date 2016-05-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00425 Chorismate_bind chorismate binding enzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.120.10 Alpha Beta 4-Layer Sandwich Anthranilate synthase Anthranilate synthase 5jxzA00
3VEHA 3HWOA 5CWAA 1I7QA 3GSEA 5JY4A 2FN0A 3OS6A 1K0EA 3ST6A 4GRHA 1I7SA 1QDLA 3R75A 5JY9A 3H9MA 5JZDA 5JY4B 3RV6A 2G5FA 2EUAA 3LOGA 3RV7A 3RV8A 3BZMA 5JXZA 2FN1A 5JY8A 2I6YA 3R74A 3RV9A 1I1QA 5KCKA 3BZNA 3R76A 1K0GA
chains in the Genus database with same CATH superfamily
3VEHA 3HWOA 5CWAA 1I7QA 3GSEA 5JY4A 2FN0A 3OS6A 1K0EA 3ST6A 4GRHA 1I7SA 1QDLA 3R75A 5JY9A 3H9MA 5JZDA 5JY4B 3RV6A 2G5FA 2EUAA 3LOGA 3RV7A 3RV8A 3BZMA 5JXZA 2FN1A 5JY8A 2I6YA 3R74A 3RV9A 1I1QA 5KCKA 3BZNA 3R76A 1K0GA
chains in the Genus database with same CATH topology
3VEHA 3HWOA 5CWAA 1I7QA 3GSEA 5JY4A 2FN0A 3OS6A 1K0EA 3ST6A 4GRHA 1I7SA 1QDLA 3R75A 5JY9A 3H9MA 5JZDA 5JY4B 3RV6A 2G5FA 2EUAA 3LOGA 3RV7A 3RV8A 3BZMA 5JXZA 2FN1A 5JY8A 2I6YA 3R74A 3RV9A 1I1QA 5KCKA 3BZNA 3R76A 1K0GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3VEH A;  3HWO A;  5CWA A;  1I7Q A;  3GSE A;  5JY4 A;  2FN0 A;  3OS6 A;  1K0E A;  3ST6 A;  4GRH A;  1I7S A;  1QDL A;  3R75 A;  5JY9 A;  3H9M A;  5JZD A;  5JY4 B;  3RV6 A;  2G5F A;  2EUA A;  3LOG A;  3RV7 A;  3RV8 A;  3BZM A;  5JXZ A;  2FN1 A;  5JY8 A;  2I6Y A;  3R74 A;  3RV9 A;  1I1Q A;  5KCK A;  3BZN A;  3R76 A;  1K0G A; 
#chains in the Genus database with same CATH topology
 3VEH A;  3HWO A;  5CWA A;  1I7Q A;  3GSE A;  5JY4 A;  2FN0 A;  3OS6 A;  1K0E A;  3ST6 A;  4GRH A;  1I7S A;  1QDL A;  3R75 A;  5JY9 A;  3H9M A;  5JZD A;  5JY4 B;  3RV6 A;  2G5F A;  2EUA A;  3LOG A;  3RV7 A;  3RV8 A;  3BZM A;  5JXZ A;  2FN1 A;  5JY8 A;  2I6Y A;  3R74 A;  3RV9 A;  1I1Q A;  5KCK A;  3BZN A;  3R76 A;  1K0G A; 
#chains in the Genus database with same CATH homology
 3VEH A;  3HWO A;  5CWA A;  1I7Q A;  3GSE A;  5JY4 A;  2FN0 A;  3OS6 A;  1K0E A;  3ST6 A;  4GRH A;  1I7S A;  1QDL A;  3R75 A;  5JY9 A;  3H9M A;  5JZD A;  5JY4 B;  3RV6 A;  2G5F A;  2EUA A;  3LOG A;  3RV7 A;  3RV8 A;  3BZM A;  5JXZ A;  2FN1 A;  5JY8 A;  2I6Y A;  3R74 A;  3RV9 A;  1I1Q A;  5KCK A;  3BZN A;  3R76 A;  1K0G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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