|
45
|
159
|
8ucxA |
Dihydrofolate reductase complexed with folate |
|
137
|
494
|
8daeA |
Arabidopsis thaliana bifunctional dihydrofolate reductase-thymidylate synthase |
|
46
|
159
|
8daiA |
E. coli dhfr complex with nadp+ and 10-methylfolate |
|
56
|
202
|
8a0zA |
Crystal structure of candida auris dihydrofolate reductase complexed with nadph and pyrimethamine |
|
62
|
212
|
8a0nB |
Crystal structure of candida auris dihydrofolate reductase complexed with nadph |
|
57
|
202
|
7zzxB |
Crystal structure of candida auris dhfr in apo form |
|
39
|
162
|
8szeA |
Crystal structure of yersinia pestis dihydrofolate reductase in complex with trimethoprim |
|
40
|
161
|
8szdA |
Crystal structure of yersinia pestis dihydrofolate reductase at 1.25-a resolution |
|
49
|
162
|
8ssxA |
Crystal structure of bacillus anthracis dihydrofolate reductase at 1.65-a resolution |
|
52
|
181
|
8e4fA |
Crystal structure of dihydrofolate reductase (dhfr) from the filarial nematode w. bancrofti in complex with nadph and folate |
|
45
|
157
|
7mylA |
Crystal structure of dfra1 dihydrofolate reductase in complex with trimethoprim |
|
40
|
158
|
7mymA |
Crystal structure of escherichia coli dihydrofolate reductase in complex with trimethoprim and nadph |
|
49
|
157
|
7rgkA |
Dfra5 complexed with nadph and 5-(3-(7-(4-(aminomethyl)phenyl)benzo[d][1,3]dioxol-5-yl)but-1-yn-1-yl)-6-ethylpyrimidine-2,4-diamine (ucp1223) |
|
48
|
157
|
7rgoA |
Dfra5 complexed with nadph and 4'-chloro-3'-(4-(2,4-diamino-6-ethylpyrimidin-5-yl)but-3-yn-2-yl)-[1,1'-biphenyl]-4-carboxamide (ucp1228) |
|
47
|
156
|
7rgjA |
Dfra1 complexed with nadph and 5-(3-(7-(4-(aminomethyl)phenyl)benzo[d][1,3]dioxol-5-yl)but-1-yn-1-yl)-6-ethylpyrimidine-2,4-diamine (ucp1223) |
|
42
|
167
|
8f09A |
Crystal structure of a trimethoprim-resistant dihydrofolate reductase (dhfr) enzyme from an uncultured soil bacterium |
|
48
|
164
|
7tj3A |
Crystal structure of a dihydrofolate reductase fola from stenotrophomonas maltophilia bound to nadp and p218 |
|
40
|
161
|
7rebA |
E. coli dihydrofolate reductase complexed with 5-(3-(7-(4-(aminomethyl)phenyl)benzo[d][1,3]dioxol-5-yl)but-1-yn-1-yl)-6-ethylpyrimidine-2,4-diamine (ucp1223) |
|
46
|
157
|
7regA |
Dfra1 complexed with nadph and 4'-chloro-3'-(4-(2,4-diamino-6-ethylpyrimidin-5-yl)but-3-yn-2-yl)-[1,1'-biphenyl]-4-carboxamide (ucp1228) |
|
163
|
608
|
7f3zA |
Double mutant plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts-k1, c59r+s108n) complexed with trimethoprim (top), nadph and dump |
|
167
|
608
|
7f3yA |
Wild-type plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with methotrexate (mtx), nadph and dump |
|
45
|
164
|
7km8A |
Crystal structure of dihydrofolate reductase (dhfr) from mycobacterium ulcerans agy99 in complex with nadp and inhibitor sddc-0001914, orthorhombic crystal from |
|
40
|
163
|
7km9A |
Crystal structure of dihydrofolate reductase (dhfr) from mycobacterium ulcerans agy99 in complex with nadp and inhibitor sddc-0001913, tetragonal crystal from |
|
42
|
163
|
7ki8A |
Crystal structure of dihydrofolate reductase (dhfr) from mycobacterium ulcerans agy99 in complex with nadp and inhibitor sddc-0001580 |
|
44
|
170
|
7ki9A |
Crystal structure of dihydrofolate reductase (dhfr) from mycobacterium ulcerans agy99 in complex with nadp and inhibitor sddc-0001912 |
|
40
|
163
|
7km7A |
Crystal structure of dihydrofolate reductase (dhfr) from mycobacterium ulcerans agy99 in complex with nadp and inhibitor sddc-0001914, tetragonal crystal from |
|
44
|
159
|
7d6gA |
Neutron crystal structure of e.coli dihydrofolate reductase complexed with folate and nadp+ at ph4.5 |
|
41
|
159
|
7d49A |
X-ray crystal structure of e.coli dihydrofolate reductase complexed with folate and nadp+ at ph4.5 |
|
43
|
159
|
7d4xA |
X-ray crystal structure of e.coli dihydrofolate reductase complexed with folate and nadp+ at ph7.0 |
|
46
|
159
|
7d4lA |
X-ray crystal structure of e.coli dihydrofolate reductase complexed with folate and nadp+ at ph7.0 |
|
46
|
185
|
7eseA |
The crystal structure of human dhfr from biortus |
|
139
|
602
|
7ctyA |
Wild type plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts), fragment 263, nadp+, dump |
|
40
|
159
|
7k6cA |
Crystal structure of dihydrofolate reductase (dhfr) from mycobacterium abscessus atcc 19977 / dsm 44196 with nadp and inhibitor p218 |
|
44
|
159
|
7lvcA |
E. coli dhfr by native mn,p,s-sad at room temperature |
|
43
|
163
|
7k68A |
Crystal structure of dihydrofolate reductase (dhfr) from mycobacterium ulcerans agy99 in complex with nadp and inhibitor sddc-0001565 |
|
45
|
165
|
7k62A |
Crystal structure of dihydrofolate reductase from mycobacterium kansasii in complex with nadp and inhibitor p218 |
|
45
|
163
|
7k69A |
Crystal structure of dihydrofolate reductase (dhfr) from mycobacterium ulcerans agy99 in complex with nadp and inhibitor sddc-0001574 |
|
45
|
163
|
7k6aA |
Crystal structure of dihydrofolate reductase (dhfr) from mycobacterium ulcerans agy99 in complex with nadp and inhibitor sddc-0001575 |
|
156
|
602
|
6lhiA |
Quadruple mutant (n51i+c59r+s108n+i164l) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with c466 (compound 42) and nadph |
|
167
|
602
|
6lezA |
Quadruple mutant (n51i+c59r+s108n+i164l) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with compound 46 and nadph |
|
150
|
602
|
6lh9A |
Quadruple mutant (n51i+c59r+s108n+i164l) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with compound 46 and nadph |
|
165
|
603
|
6leuA |
Quadruple mutant (n51i+c59r+s108n+i164l) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with compound 42 and nadph |
|
170
|
608
|
6lhjA |
Quadruple mutant (n51i+c59r+s108n+i164l) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with c452 (compound 16) and nadph |
|
168
|
602
|
6levA |
Quadruple mutant (n51i+c59r+s108n+i164l) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with compound 46 and nadph |
|
41
|
163
|
6uwqA |
Crystal structure of dihydrofolate reductase from mycobacterium ulcerans with sddc-0001565 inhibitor |
|
45
|
163
|
6uwwA |
Crystal structure of dihydrofolate reductase from mycobacterium ulcerans with p218 inhibitor |
|
51
|
184
|
6vcjA |
Crystal structure of hsdhfr in complex with nadp+, dap, and r-naproxen |
|
41
|
156
|
7l9tA |
Crystal structure of dihydrofolate reductase from mycolicibacterium smegmatis in complex with sddc-0001565 inhibitor |
|
43
|
159
|
6vs9A |
Mycobacterium tuberculosis dihydrofolate reductase in complex with 3-(piperidin-1-ylmethyl)benzoic acid(fragment 11) |
|
42
|
159
|
6vsfA |
Mycobacterium tuberculosis dihydrofolate reductase in complex with 4-(3,4-dihydro-2h-benzo[b][1,4]dioxepin-7-yl)-4-oxobutanoic acid(fragment 16) |
