1A3AA

Crystal structure of iia mannitol from escherichia coli
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
145
structure length
145
Chain Sequence
LFKLGAENIFLGRKAATKEEAIRFAGEQLVKGGYVEPEYVQAMLDREKLTPTYLGESIAVPHGTVEAKDRVLKTGVVFCQYPEGVRFGEEEDDIARLVIGIAARNNEHIQVITSLTNALDDESVIERLAHTTSVDEVLELLAGRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of the Escherichia coli phosphotransferase IIAmannitol reveals a novel fold with two conformations of the active site.
pubmed doi rcsb
molecule keywords MANNITOL-SPECIFIC EII
molecule tags Phosphotransferase
source organism Escherichia coli
total genus 49
structure length 145
sequence length 145
chains with identical sequence B, C, D
ec nomenclature ec 2.7.1.197: Protein-N(pi)-phosphohistidine--D-mannitol phosphotransferase.
pdb deposition date 1998-01-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00359 PTS_EIIA_2 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.930.10 Alpha Beta 3-Layer(aba) Sandwich Mannitol-specific EII; Chain A Mannitol-specific EII; Chain A 1a3aA00
3OXPA 4ODXX 4M8QC 2FEWA 3URRA 1XIZA 3LF6A 4KY9A 4GQXA 1A6JA 2OQTA 3T43A 1A3AA 1J6TA 3BJVA 2OQ3A 4M62S 1HYNP 2A0JA
chains in the Genus database with same CATH superfamily
3OXPA 4ODXX 4M8QC 2FEWA 3URRA 1XIZA 3LF6A 4KY9A 4GQXA 1A6JA 2OQTA 3T43A 1A3AA 1J6TA 3BJVA 2OQ3A 4M62S 1HYNP 2A0JA
chains in the Genus database with same CATH topology
3OXPA 4ODXX 4M8QC 2FEWA 3URRA 1XIZA 3LF6A 4KY9A 4GQXA 1A6JA 2OQTA 3T43A 1A3AA 1J6TA 3BJVA 2OQ3A 4M62S 1HYNP 2A0JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OXP A;  4ODX X;  4M8Q C;  2FEW A;  3URR A;  1XIZ A;  3LF6 A;  4KY9 A;  4GQX A;  1A6J A;  2OQT A;  3T43 A;  1A3A A;  1J6T A;  3BJV A;  2OQ3 A;  4M62 S;  1HYN P;  2A0J A; 
#chains in the Genus database with same CATH topology
 3OXP A;  4ODX X;  4M8Q C;  2FEW A;  3URR A;  1XIZ A;  3LF6 A;  4KY9 A;  4GQX A;  1A6J A;  2OQT A;  3T43 A;  1A3A A;  1J6T A;  3BJV A;  2OQ3 A;  4M62 S;  1HYN P;  2A0J A; 
#chains in the Genus database with same CATH homology
 3OXP A;  4ODX X;  4M8Q C;  2FEW A;  3URR A;  1XIZ A;  3LF6 A;  4KY9 A;  4GQX A;  1A6J A;  2OQT A;  3T43 A;  1A3A A;  1J6T A;  3BJV A;  2OQ3 A;  4M62 S;  1HYN P;  2A0J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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