4M8QC

Ontogeny of recognition specificity and functionality for the anti-hiv neutralizing antibody 4e10
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
148
structure length
148
Chain Sequence
HFRRHYVRHLPKEVSQNDIIKALASPLINDGMVVSDFADHVITREQNFPTGLPVEPVGVAIPHTDSKYVRQNAISVGILAEPVNFEDAGGEPDPVPVRVVFMLALGNWFDITNVLWWIMDVIQDEDFMQQLLVMNDDEIYQSIYTRIS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Immune system
molecule keywords GEP1 Fv heavy chain
publication title Ontogeny of Recognition Specificity and Functionality for the Broadly Neutralizing Anti-HIV Antibody 4E10.
pubmed doi rcsb
source organism Homo sapiens
total genus 33
structure length 148
sequence length 148
chains with identical sequence S
ec nomenclature
pdb deposition date 2013-08-13
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.930.10 Alpha Beta 3-Layer(aba) Sandwich Mannitol-specific EII; Chain A Mannitol-specific EII; Chain A 4m8qC00
3T43A 1XIZA 4ODXX 2OQ3A 4KY9A 4M62S 1HYNP 4GQXA 2A0JA 2OQTA 4M8QC 1A6JA 3OXPA 2FEWA 3BJVA 1A3AA 1J6TA 3URRA 3LF6A
chains in the Genus database with same CATH superfamily
3T43A 1XIZA 4ODXX 2OQ3A 4KY9A 4M62S 1HYNP 4GQXA 2A0JA 2OQTA 4M8QC 1A6JA 3OXPA 2FEWA 3BJVA 1A3AA 1J6TA 3URRA 3LF6A
chains in the Genus database with same CATH topology
3T43A 1XIZA 4ODXX 2OQ3A 4KY9A 4M62S 1HYNP 4GQXA 2A0JA 2OQTA 4M8QC 1A6JA 3OXPA 2FEWA 3BJVA 1A3AA 1J6TA 3URRA 3LF6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3T43 A;  1XIZ A;  4ODX X;  2OQ3 A;  4KY9 A;  4M62 S;  1HYN P;  4GQX A;  2A0J A;  2OQT A;  4M8Q C;  1A6J A;  3OXP A;  2FEW A;  3BJV A;  1A3A A;  1J6T A;  3URR A;  3LF6 A; 
#chains in the Genus database with same CATH topology
 3T43 A;  1XIZ A;  4ODX X;  2OQ3 A;  4KY9 A;  4M62 S;  1HYN P;  4GQX A;  2A0J A;  2OQT A;  4M8Q C;  1A6J A;  3OXP A;  2FEW A;  3BJV A;  1A3A A;  1J6T A;  3URR A;  3LF6 A; 
#chains in the Genus database with same CATH homology
 3T43 A;  1XIZ A;  4ODX X;  2OQ3 A;  4KY9 A;  4M62 S;  1HYN P;  4GQX A;  2A0J A;  2OQT A;  4M8Q C;  1A6J A;  3OXP A;  2FEW A;  3BJV A;  1A3A A;  1J6T A;  3URR A;  3LF6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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