4M62S

Ontogeny of recognition specificity and functionality for the anti-hiv neutralizing antibody 4e10
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
155
structure length
155
Chain Sequence
NAMQGIHFRRHYVRHLPKEVSQNDIIKALASPLINDGMVVSDFADHVITREQNFPTGLPVEPVGVAIPHTDSKYVRQNAISVGILAEPVNFEDAGGEPDPVPVRVVFMLALGNWFDITNVLWWIMDVIQDEDFMQQLLVMNDDEIYQSIYTRISE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Immune system
molecule keywords GEP2 FV light chain
publication title Ontogeny of Recognition Specificity and Functionality for the Broadly Neutralizing Anti-HIV Antibody 4E10.
pubmed doi rcsb
source organism Homo sapiens
total genus 45
structure length 155
sequence length 155
chains with identical sequence T
ec nomenclature
pdb deposition date 2013-08-08
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.930.10 Alpha Beta 3-Layer(aba) Sandwich Mannitol-specific EII; Chain A Mannitol-specific EII; Chain A 4m62S00
2FEWA 2OQ3A 3OXPA 1A3AA 3T43A 4KY9A 3URRA 4GQXA 2A0JA 4M8QC 4ODXX 2OQTA 1HYNP 1J6TA 3BJVA 3LF6A 4M62S 1XIZA 1A6JA
chains in the Genus database with same CATH superfamily
2FEWA 2OQ3A 3OXPA 1A3AA 3T43A 4KY9A 3URRA 4GQXA 2A0JA 4M8QC 4ODXX 2OQTA 1HYNP 1J6TA 3BJVA 3LF6A 4M62S 1XIZA 1A6JA
chains in the Genus database with same CATH topology
2FEWA 2OQ3A 3OXPA 1A3AA 3T43A 4KY9A 3URRA 4GQXA 2A0JA 4M8QC 4ODXX 2OQTA 1HYNP 1J6TA 3BJVA 3LF6A 4M62S 1XIZA 1A6JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FEW A;  2OQ3 A;  3OXP A;  1A3A A;  3T43 A;  4KY9 A;  3URR A;  4GQX A;  2A0J A;  4M8Q C;  4ODX X;  2OQT A;  1HYN P;  1J6T A;  3BJV A;  3LF6 A;  4M62 S;  1XIZ A;  1A6J A; 
#chains in the Genus database with same CATH topology
 2FEW A;  2OQ3 A;  3OXP A;  1A3A A;  3T43 A;  4KY9 A;  3URR A;  4GQX A;  2A0J A;  4M8Q C;  4ODX X;  2OQT A;  1HYN P;  1J6T A;  3BJV A;  3LF6 A;  4M62 S;  1XIZ A;  1A6J A; 
#chains in the Genus database with same CATH homology
 2FEW A;  2OQ3 A;  3OXP A;  1A3A A;  3T43 A;  4KY9 A;  3URR A;  4GQX A;  2A0J A;  4M8Q C;  4ODX X;  2OQT A;  1HYN P;  1J6T A;  3BJV A;  3LF6 A;  4M62 S;  1XIZ A;  1A6J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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