1NF1A

The gap related domain of neurofibromin
Total Genus 79
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
79
sequence length
324
structure length
260
Chain Sequence
ERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLSLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHCLYQVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAPIIERGLKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAARRFFLDIASALHRLLWNNQEKIGQYLSSRPFDKMATLLAYLGPPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural analysis of the GAP-related domain from neurofibromin and its implications.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTEIN (NEUROFIBROMIN)
total genus 79
structure length 260
sequence length 324
ec nomenclature
pdb deposition date 1998-07-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00616 RasGAP GTPase-activator protein for Ras-like GTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.506.10 Mainly Alpha Orthogonal Bundle GTPase Activation - p120GAP; domain 1 GTPase Activation - p120gap; domain 1 1nf1A02
1.10.506.10 Mainly Alpha Orthogonal Bundle GTPase Activation - p120GAP; domain 1 GTPase Activation - p120gap; domain 1 1nf1A01
4M8MA 3BXJA 3IG3A 3HM6X 5E6PA 3SU8X 4M8NA 3FAYA 3RYTA 1WQ1G 1NF1A 1WERA
chains in the Genus database with same CATH superfamily
4M8MA 3BXJA 3IG3A 3HM6X 5E6PA 3SU8X 4M8NA 3FAYA 3RYTA 1WQ1G 1NF1A 1WERA
chains in the Genus database with same CATH topology
4M8MA 3BXJA 3IG3A 3HM6X 5E6PA 3SU8X 4M8NA 3FAYA 3RYTA 1WQ1G 1NF1A 1WERA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4M8M A;  3BXJ A;  3IG3 A;  3HM6 X;  5E6P A;  3SU8 X;  4M8N A;  3FAY A;  3RYT A;  1WQ1 G;  1NF1 A;  1WER A; 
#chains in the Genus database with same CATH topology
 4M8M A;  3BXJ A;  3IG3 A;  3HM6 X;  5E6P A;  3SU8 X;  4M8N A;  3FAY A;  3RYT A;  1WQ1 G;  1NF1 A;  1WER A; 
#chains in the Genus database with same CATH homology
 4M8M A;  3BXJ A;  3IG3 A;  3HM6 X;  5E6P A;  3SU8 X;  4M8N A;  3FAY A;  3RYT A;  1WQ1 G;  1NF1 A;  1WER A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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