The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
108
|
sequence length |
476
|
structure length |
348
|
Chain Sequence |
NKDNSRRVDNVLEHFEFNFTEQWYLKARYQTMSILPMELYKEFAEYVTNHYRMLCAVLEPALNVKGKEEVASALVHILQSTGKAKDFLSDMAMSEVDRFMEREHLIFRENTLATKAIEEYMRLIGQKYLKDAIGEFIRALYESEENCEVDPIKCTASSLAEHQANLRMCCELALCKVVNSHCVFPRELKEVFASWRLRCAERGREDIADRLISASLFLRFLCPAIMSPSLFGLMQEYPDEQTSRTLTLIAKVIQNLANFSKFTSKEDFLGFMNEFLELEWGSMQQFLYEISNLDTLTNSSGYIDLGRELSTLHALLWEVLPQLSKEALLKLGPLPRLLSDISTALRNP
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
The C2 domain of SynGAP is essential for stimulation of the Rap GTPase reaction.
pubmed doi rcsb |
| molecule tags |
Signaling protein
|
| source organism |
Rattus norvegicus
|
| molecule keywords |
Ras GTPase-activating protein SynGAP
|
| total genus |
108
|
| structure length |
348
|
| sequence length |
476
|
| chains with identical sequence |
B
|
| ec nomenclature | |
| pdb deposition date | 2008-01-14 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00168 | C2 | C2 domain |
| A | PF00616 | RasGAP | GTPase-activator protein for Ras-like GTPase |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Orthogonal Bundle | GTPase Activation - p120GAP; domain 1 | GTPase Activation - p120gap; domain 1 | ||
| Mainly Alpha | Orthogonal Bundle | GTPase Activation - p120GAP; domain 1 | GTPase Activation - p120GAP; domain 1 | ||
| Mainly Beta | Single Sheet | GTPase activation domain, GAP fold | p120GAP domain-like |
#chains in the Genus database with same CATH superfamily 4M8N A; 3HM6 X; 4M8M A; 1WQ1 G; 1WER A; 3RYT A; 3FAY A; 1NF1 A; 3SU8 X; 3BXJ A; 5E6P A; 3IG3 A; #chains in the Genus database with same CATH topology 4M8N A; 3HM6 X; 4M8M A; 1WQ1 G; 1WER A; 3RYT A; 3FAY A; 1NF1 A; 3SU8 X; 3BXJ A; 5E6P A; 3IG3 A; #chains in the Genus database with same CATH homology 4M8N A; 3HM6 X; 4M8M A; 1WQ1 G; 1WER A; 3RYT A; 3FAY A; 1NF1 A; 3SU8 X; 3BXJ A; 5E6P A; 3IG3 A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
