The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
40
|
sequence length |
160
|
structure length |
160
|
Chain Sequence |
STRRVSVRDKLLVKEVAELEANLPCTCKVHFPDPNKLHCFQLTVTPDEGYYQGGKFQFETEVPDAYNMVPPKVKCLTKIWHPNITETGEICLSLLREHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFDDPLNIEAAEHHLRDKEDFRNKVDDYIKRYAR
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification
pubmed doi rcsb |
| molecule keywords |
NEDD8-activating enzyme E1 catalytic subunit
|
| molecule tags |
Ligase
|
| source organism |
Homo sapiens
|
| total genus |
40
|
| structure length |
160
|
| sequence length |
160
|
| ec nomenclature |
ec
2.3.2.32: Cullin-RING-type E3 NEDD8 transferase. |
| pdb deposition date | 2008-12-22 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| B | PF00179 | UQ_con | Ubiquitin-conjugating enzyme |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | Roll | Ubiquitin Conjugating Enzyme | Ubiquitin Conjugating Enzyme |
#chains in the Genus database with same CATH superfamily 1J74 A; 2FO3 A; 4DDG A; 2C4P A; 4WZ3 A; 4ONM A; 2YB6 A; 4ONN B; 2CYX A; 4ZNY A; 4V3L A; 4TKP A; 4II2 C; 1AYZ A; 4ONL B; 3W31 B; 4AUQ A; 4NRG A; 1YH2 A; 1ZGU A; 3WE5 A; 2FUH A; 2C2V B; 2Y9P A; 3UIP A; 2Z5D A; 5KNL C; 2YZ0 A; 3L1Y A; 3HCT B; 4NR3 A; 4P5O G; 5F6E A; 1JAT A; 1Z5S A; 2O25 C; 5F6D A; 3UIN A; 3R42 A; 4DDI A; 3TGD A; 2AAK A; 5F6W A; 2ESK A; 3EB6 B; 2CLW A; 3BZH A; 3OJ4 A; 3VON B; 3OBS A; 1TTE A; 4L83 A; 4W5V A; 1J7D A; 2ESO A; 4NRI B; 5AIT B; 4IP3 B; 2GRR A; 2H2Y A; 4GPR A; 4Q5H C; 2PX9 B; 1JAS A; 1A3S A; 5FQ2 A; 3RCZ B; 2GMI A; 1YF9 A; 2Z6O A; 2MT6 A; 4DS2 A; 1KPQ A; 1X23 A; 1S1Q A; 4YC1 A; 4LDT C; 4S3O A; 3EVX A; 2BEP A; 4LAD A; 3R3Q A; 3OBU A; 2ESP A; 2EKE A; 3A4S A; 2GJD A; 2GRO A; 3ZNI C; 3E46 A; 2AWF A; 2K07 A; 1Y8X A; 3ONG B; 4ONL A; 1YLA A; 1I7K A; 2DAX A; 4NRG B; 4DHI D; 3FN1 B; 3RZ3 A; 5D1K A; 3HCU B; 3CEG A; 4BWF A; 3ZQS A; 2AYV A; 4BVU B; 1YRV A; 5AIU B; 2PE6 A; 1JAT B; 1U9B A; 2YBF A; 2OB4 A; 4V3K A; 1QCQ A; 5F6U A; 5D0K A; 4JQU A; 2VRR A; 2F4Z A; 3SQV C; 4FH1 A; 4A4C C; 2HLW A; 1J7D B; 3O2U A; 1ZUO A; 3H8K A; 1M4Q A; 3PTF A; 5F6X A; 1Q34 A; 2EBM A; 4CCG A; 4R62 A; 2A4D A; 2Q0V A; 4JUE A; 5EGG A; 2F0R A; 3L1Z A; 4ONM B; 3OBQ A; 2DAW A; 2QGX A; 4ONN A; 1UZX A; 2F4W A; 2GMI B; 1Z2U A; 2YHO B; 2NVU C; 2UCZ A; 1FZY A; 3JVZ A; 1WZV A; 1U9A A; 2GRP A; 5IFR A; 2Z6P A; 3A33 A; 3UGB A; 1KPS A; 2ESQ A; 2Y4W A; 1FXT A; 5AIE B; 5D1M A; 5F6V A; 5JNE B; 2C2V C; 3JW0 A; 2GRN A; 5D1L A; 1PZV A; 4YII U; 5AIT D; 5D0M A; 2XWU A; 2R0J A; 2DAY A; 2GRQ A; 4AP4 B; 1M4P A; 4NR3 B; 1FBV C; 3RPG A; 2BF8 A; 3P9H A; 3E95 C; 3E95 A; 2PWQ A; 1ZDN A; 2A7L A; 4M1N A; 2CLW B; 2Y9M A; 3K9O A; 4Y1L A; 4Y1L C; 3VON C; 1WZW A; 5DFL A; 1UKX A; 4A4B C; 1Y6L A; 5HPT C; 4QPL B; 2LXP A; 5F6Y A; 4A49 B; 1Z3D A; 4NRI A; 1C4Z D; 5D2M A; 3OBX A; 4Q5E C; 3P9G A; 3SY2 C; 4MDK A; 2DMF A; 2OXQ A; 2O25 A; 4DHZ F; 2KJH A; 3F92 A; 2EBK A; 3K9P A; 1JBB A; 3UIO A; 2ONU A; 2UYZ A; 2EDI A; 2KLY A; 3KPA A; 4DHJ C; 1KPP A; 2E2C A; 4X57 A; 4EJE A; 3FSH A; 1W4U A; 5FER B; #chains in the Genus database with same CATH topology 1J74 A; 2FO3 A; 4DDG A; 2C4P A; 4WZ3 A; 4ONM A; 2YB6 A; 4ONN B; 2CYX A; 4ZNY A; 4V3L A; 4TKP A; 4II2 C; 1AYZ A; 4ONL B; 3W31 B; 4AUQ A; 4NRG A; 1YH2 A; 1ZGU A; 3WE5 A; 2FUH A; 2C2V B; 2Y9P A; 3UIP A; 2Z5D A; 5KNL C; 2YZ0 A; 3L1Y A; 3HCT B; 4NR3 A; 4P5O G; 5F6E A; 1JAT A; 1Z5S A; 2O25 C; 5F6D A; 3UIN A; 3R42 A; 4DDI A; 3TGD A; 2AAK A; 5F6W A; 2ESK A; 3EB6 B; 2CLW A; 3BZH A; 3OJ4 A; 3VON B; 3OBS A; 1TTE A; 4L83 A; 4W5V A; 1J7D A; 2ESO A; 4NRI B; 5AIT B; 4IP3 B; 2GRR A; 2H2Y A; 4GPR A; 4Q5H C; 2PX9 B; 1JAS A; 1A3S A; 5FQ2 A; 3RCZ B; 2GMI A; 1YF9 A; 2Z6O A; 2MT6 A; 4DS2 A; 1KPQ A; 1X23 A; 1S1Q A; 4YC1 A; 4LDT C; 4S3O A; 3EVX A; 2BEP A; 4LAD A; 3R3Q A; 3OBU A; 2ESP A; 2EKE A; 3A4S A; 2GJD A; 2GRO A; 3ZNI C; 3E46 A; 2AWF A; 2K07 A; 1Y8X A; 3ONG B; 4ONL A; 1YLA A; 1I7K A; 2DAX A; 4NRG B; 4DHI D; 3FN1 B; 3RZ3 A; 5D1K A; 3HCU B; 3CEG A; 4BWF A; 3ZQS A; 2AYV A; 4BVU B; 1YRV A; 5AIU B; 2PE6 A; 1JAT B; 1U9B A; 2YBF A; 2OB4 A; 4V3K A; 1QCQ A; 5F6U A; 5D0K A; 4JQU A; 2VRR A; 2F4Z A; 3SQV C; 4FH1 A; 4A4C C; 2HLW A; 1J7D B; 3O2U A; 1ZUO A; 3H8K A; 1M4Q A; 3PTF A; 5F6X A; 1Q34 A; 2EBM A; 4CCG A; 4R62 A; 2A4D A; 2Q0V A; 4JUE A; 5EGG A; 2F0R A; 3L1Z A; 4ONM B; 3OBQ A; 2DAW A; 2QGX A; 4ONN A; 1UZX A; 2F4W A; 2GMI B; 1Z2U A; 2YHO B; 2NVU C; 2UCZ A; 1FZY A; 3JVZ A; 1WZV A; 1U9A A; 2GRP A; 5IFR A; 2Z6P A; 3A33 A; 3UGB A; 1KPS A; 2ESQ A; 2Y4W A; 1FXT A; 5AIE B; 5D1M A; 5F6V A; 5JNE B; 2C2V C; 3JW0 A; 2GRN A; 5D1L A; 1PZV A; 4YII U; 5AIT D; 5D0M A; 2XWU A; 2R0J A; 2DAY A; 2GRQ A; 4AP4 B; 1M4P A; 4NR3 B; 1FBV C; 3RPG A; 2BF8 A; 3P9H A; 3E95 C; 3E95 A; 2PWQ A; 1ZDN A; 2A7L A; 4M1N A; 2CLW B; 2Y9M A; 3K9O A; 4Y1L A; 4Y1L C; 3VON C; 1WZW A; 5DFL A; 1UKX A; 4A4B C; 1Y6L A; 5HPT C; 4QPL B; 2LXP A; 5F6Y A; 4A49 B; 1Z3D A; 4NRI A; 1C4Z D; 5D2M A; 3OBX A; 4Q5E C; 3P9G A; 3SY2 C; 4MDK A; 2DMF A; 2OXQ A; 2O25 A; 4DHZ F; 2KJH A; 3F92 A; 2EBK A; 3K9P A; 1JBB A; 3UIO A; 2ONU A; 2UYZ A; 2EDI A; 2KLY A; 3KPA A; 4DHJ C; 1KPP A; 2E2C A; 4X57 A; 4EJE A; 3FSH A; 1W4U A; 5FER B; #chains in the Genus database with same CATH homology 1J74 A; 2FO3 A; 4DDG A; 2C4P A; 4WZ3 A; 4ONM A; 2YB6 A; 4ONN B; 2CYX A; 4ZNY A; 4V3L A; 4TKP A; 4II2 C; 1AYZ A; 4ONL B; 3W31 B; 4AUQ A; 4NRG A; 1YH2 A; 1ZGU A; 3WE5 A; 2FUH A; 2C2V B; 2Y9P A; 3UIP A; 2Z5D A; 5KNL C; 2YZ0 A; 3L1Y A; 3HCT B; 4NR3 A; 4P5O G; 5F6E A; 1JAT A; 1Z5S A; 2O25 C; 5F6D A; 3UIN A; 3R42 A; 4DDI A; 3TGD A; 2AAK A; 5F6W A; 2ESK A; 3EB6 B; 2CLW A; 3BZH A; 3OJ4 A; 3VON B; 3OBS A; 1TTE A; 4L83 A; 4W5V A; 1J7D A; 2ESO A; 4NRI B; 5AIT B; 4IP3 B; 2GRR A; 2H2Y A; 4GPR A; 4Q5H C; 2PX9 B; 1JAS A; 1A3S A; 5FQ2 A; 3RCZ B; 2GMI A; 1YF9 A; 2Z6O A; 2MT6 A; 4DS2 A; 1KPQ A; 1X23 A; 1S1Q A; 4YC1 A; 4LDT C; 4S3O A; 3EVX A; 2BEP A; 4LAD A; 3R3Q A; 3OBU A; 2ESP A; 2EKE A; 3A4S A; 2GJD A; 2GRO A; 3ZNI C; 3E46 A; 2AWF A; 2K07 A; 1Y8X A; 3ONG B; 4ONL A; 1YLA A; 1I7K A; 2DAX A; 4NRG B; 4DHI D; 3FN1 B; 3RZ3 A; 5D1K A; 3HCU B; 3CEG A; 4BWF A; 3ZQS A; 2AYV A; 4BVU B; 1YRV A; 5AIU B; 2PE6 A; 1JAT B; 1U9B A; 2YBF A; 2OB4 A; 4V3K A; 1QCQ A; 5F6U A; 5D0K A; 4JQU A; 2VRR A; 2F4Z A; 3SQV C; 4FH1 A; 4A4C C; 2HLW A; 1J7D B; 3O2U A; 1ZUO A; 3H8K A; 1M4Q A; 3PTF A; 5F6X A; 1Q34 A; 2EBM A; 4CCG A; 4R62 A; 2A4D A; 2Q0V A; 4JUE A; 5EGG A; 2F0R A; 3L1Z A; 4ONM B; 3OBQ A; 2DAW A; 2QGX A; 4ONN A; 1UZX A; 2F4W A; 2GMI B; 1Z2U A; 2YHO B; 2NVU C; 2UCZ A; 1FZY A; 3JVZ A; 1WZV A; 1U9A A; 2GRP A; 5IFR A; 2Z6P A; 3A33 A; 3UGB A; 1KPS A; 2ESQ A; 2Y4W A; 1FXT A; 5AIE B; 5D1M A; 5F6V A; 5JNE B; 2C2V C; 3JW0 A; 2GRN A; 5D1L A; 1PZV A; 4YII U; 5AIT D; 5D0M A; 2XWU A; 2R0J A; 2DAY A; 2GRQ A; 4AP4 B; 1M4P A; 4NR3 B; 1FBV C; 3RPG A; 2BF8 A; 3P9H A; 3E95 C; 3E95 A; 2PWQ A; 1ZDN A; 2A7L A; 4M1N A; 2CLW B; 2Y9M A; 3K9O A; 4Y1L A; 4Y1L C; 3VON C; 1WZW A; 5DFL A; 1UKX A; 4A4B C; 1Y6L A; 5HPT C; 4QPL B; 2LXP A; 5F6Y A; 4A49 B; 1Z3D A; 4NRI A; 1C4Z D; 5D2M A; 3OBX A; 4Q5E C; 3P9G A; 3SY2 C; 4MDK A; 2DMF A; 2OXQ A; 2O25 A; 4DHZ F; 2KJH A; 3F92 A; 2EBK A; 3K9P A; 1JBB A; 3UIO A; 2ONU A; 2UYZ A; 2EDI A; 2KLY A; 3KPA A; 4DHJ C; 1KPP A; 2E2C A; 4X57 A; 4EJE A; 3FSH A; 1W4U A; 5FER B;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
