3RI0A

Epitope backbone grafting by computational design for improved presentation of linear epitopes on scaffold proteins
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
156
structure length
156
Chain Sequence
LSPSARRVQGALETRGFGHLKVVELPASTRTAKEAAQAVGAEVGQIVKSLAYGGSKGAYLFLVSGKNRLDLGKAARLVGTDLLELDKWAVAALTGFAAGGVPPVGHNTPLPAYLDEDLLGYPEVWAAGGTPRALFRATPKELLALTGAQVADLKEG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Computational design of high-affinity epitope scaffolds by backbone grafting of a linear epitope.
pubmed doi rcsb
molecule tags De novo protein
source organism Thermus thermophilus
molecule keywords BB_2cx5_001
total genus 44
structure length 156
sequence length 156
chains with identical sequence B
ec nomenclature
pdb deposition date 2011-04-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04073 tRNA_edit Aminoacyl-tRNA editing domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.960.10 Alpha Beta Alpha-Beta Complex YbaK protein YbaK/aminoacyl-tRNA synthetase-associated domain 3ri0A00
1VKIA 3RI0A 2J3MA 2CX5A 2DXAA 1DBUA 1WDVA 2Z0KA 3RIJA 1VJFA 2J3LA 1DBXA 2Z0XA 3MEMA 3OP6A
chains in the Genus database with same CATH superfamily
1VKIA 3RI0A 2J3MA 2CX5A 2DXAA 1DBUA 1WDVA 2Z0KA 3RIJA 1VJFA 2J3LA 1DBXA 2Z0XA 3MEMA 3OP6A
chains in the Genus database with same CATH topology
1VKIA 3RI0A 2J3MA 2CX5A 2DXAA 1DBUA 1WDVA 2Z0KA 3RIJA 1VJFA 2J3LA 1DBXA 2Z0XA 3MEMA 3OP6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VKI A;  3RI0 A;  2J3M A;  2CX5 A;  2DXA A;  1DBU A;  1WDV A;  2Z0K A;  3RIJ A;  1VJF A;  2J3L A;  1DBX A;  2Z0X A;  3MEM A;  3OP6 A; 
#chains in the Genus database with same CATH topology
 1VKI A;  3RI0 A;  2J3M A;  2CX5 A;  2DXA A;  1DBU A;  1WDV A;  2Z0K A;  3RIJ A;  1VJF A;  2J3L A;  1DBX A;  2Z0X A;  3MEM A;  3OP6 A; 
#chains in the Genus database with same CATH homology
 1VKI A;  3RI0 A;  2J3M A;  2CX5 A;  2DXA A;  1DBU A;  1WDV A;  2Z0K A;  3RIJ A;  1VJF A;  2J3L A;  1DBX A;  2Z0X A;  3MEM A;  3OP6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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